Estramustine sodium phosphate

Independent reference data for Estramustine sodium phosphate (CAS 52205-73-9), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Documented uses on record

• A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA,

Synonyms and trade names

Estramustine phosphate sodium; 52205-73-9; Estramustine sodium phosphate; Estracyt; Estramustine phosphate disodium; DTXSID2048953; IQ856M1R16; Ro 21-8837/001; Estradiol 3-(bis(2-chloroethyl)carbamate) 17-(dihydrogen phosphate), disodium salt; DTXCID5028879; CHEBI:31562; Ro-218837-001; ESTRAMUSTINE PHOSPHATE SODIUM ANHYDROUS; Ro-21-8837/001; Estramustine 17-(dihydrogenphosphate) disodium salt anhydrous; Estramustine 17-(dihydrogenphosphate) disodium salt monohydrate

GHS hazard classification

What the public record says

Estramustine sodium phosphate · CAS 52205-73-9 · C23H30Cl2NNa2O6P. UNII IQ856M1R16.

Source: PubChem / Wikidata; the batch COA governs where values differ.