埃索美拉唑（CAS 119141-88-7）：分子式 C17H19N3O3S、分子量 345.4。
| CAS号 | 119141-88-7 |
|---|---|
| 分子式 | C17H19N3O3S |
| 分子量 | 345.4 |
| 熔点 | 155 |
| LogP | 0.6 |
| 应用领域 | Uses: MEDICATION、Anti-Ulcer Agents、Proton Pump Inhibitors、Use (kg、approx.) in Germany (2009): >1000、Use (kg) in USA (2002): 12000、Consumption (g per capita、approx.) in Germany (2009): 0.0122、Consumption (g per capita) in the USA (2002): 0.0425、Excretion rate: 0.005、Calculated removal (%): 9.8、Used in the treatment of acid-reflux disorders (GERD)、peptic ulcer disease、H. pylori eradication、and prevention of gastroinetestinal bleeds with NSAID use. Used in the treatment of dyspepsia、peptic ulcer disease (PUD)、gastroesophageal reflux disease (GORD、GERD) and Zollinger-Ellison syndrome. [Wikipedia]、Omeprazole is indicated for the treatment of duodenal ulcers、benign gastric ulcers、gastroesophageal reflux disease (GERD)、heartburn and other symptoms associated with GERD、erosive esophagitis、and long-term treatment of pathological hypersecretory conditions like Zollinger-Ellison syndrome、multiple endocrine adenomas、and systemic mastocytosis.、Formulations、Preparations: Esomeprazole is available as delayed release capsules containing esomeprazole magnesium trihydrate ... Each capsule contains 20 or 40 mg of esomeprazole present as 22.3 or 44.5 mg of esomeprazole magnesium trihydrate. ... Esomeprazole is marketed under the trade name Nexium (AstraZeneca).、Table: Esomeprazole Magnesium Preparations [Table#8119]、Table: Esomeprazole Magnesium Combination Preparations [Table#8120]、Table: Esomeprazole Sodium Preparations [Table#8121] |
登记用途：Uses: MEDICATION、Anti-Ulcer Agents、Proton Pump Inhibitors、Use (kg、approx.) in Germany (2009): >1000、Use (kg) in USA (2002): 12000、Consumption (g per capita、approx.) in Germany (2009): 0.0122、Consumption (g per capita) in the USA (2002): 0.0425、Excretion rate: 0.005、Calculated removal (%): 9.8、Used in the treatment of acid-reflux disorders (GERD)、peptic ulcer disease、H. pylori eradication、and prevention of gastroinetestinal bleeds with NSAID use. Used in the treatment of dyspepsia、peptic ulcer disease (PUD)、gastroesophageal reflux disease (GORD、GERD) and Zollinger-Ellison syndrome. [Wikipedia]、Omeprazole is indicated for the treatment of duodenal ulcers、benign gastric ulcers、gastroesophageal reflux disease (GERD)、heartburn and other symptoms associated with GERD、erosive esophagitis、and long-term treatment of pathological hypersecretory conditions like Zollinger-Ellison syndrome、multiple endocrine adenomas、and systemic mastocytosis.、Formulations、Preparations: Esomeprazole is available as delayed release capsules containing esomeprazole magnesium trihydrate ... Each capsule contains 20 or 40 mg of esomeprazole present as 22.3 or 44.5 mg of esomeprazole magnesium trihydrate. ... Esomeprazole is marketed under the trade name Nexium (AstraZeneca).、Table: Esomeprazole Magnesium Preparations [Table#8119]、Table: Esomeprazole Magnesium Combination Preparations [Table#8120]、Table: Esomeprazole Sodium Preparations [Table#8121]。
埃索美拉唑 是一种化工化合物，登记 CAS 号为 119141-88-7，分子式 C17H19N3O3S（分子量 345.4）。
登记 CAS 号：119141-88-7
其分子式 C17H19N3O3S 由 17 个碳、19 个氢、3 个氮、3 个氧、1 个硫 组成。
别名/同义词：埃索美拉唑 · Esomeprazole
埃索美拉唑 的 CAS 登记号为 119141-88-7。
分子式 C17H19N3O3S，分子量 345.4。
别名/同义词：埃索美拉唑、Esomeprazole。
登记用途：Uses: MEDICATION、Anti-Ulcer Agents、Proton Pump Inhibitors、Use (kg、approx.) in Germany (2009): >1000、Use (kg) in USA (2002): 12000、Consumption (g per capita、approx.) in Germany (2009): 0.0122、Consumption (g per capita) in the USA (2002): 0.0425、Excretion rate: 0.005、Calculated removal (%): 9.8、Used in the treatment of acid-reflux disorders (GERD)、peptic ulcer disease、H. pylori eradication、and prevention of gastroinetestinal bleeds with NSAID use. Used in the treatment of dyspepsia、peptic ulcer disease (PUD)、gastroesophageal reflux disease (GORD、GERD) and Zollinger-Ellison syndrome. [Wikipedia]、Omeprazole is indicated for the treatment of duodenal ulcers、benign gastric ulcers、gastroesophageal reflux disease (GERD)、heartburn and other symptoms associated with GERD、erosive esophagitis、and long-term treatment of pathological hypersecretory conditions like Zollinger-Ellison syndrome、multiple endocrine adenomas、and systemic mastocytosis.、Formulations、Preparations: Esomeprazole is available as delayed release capsules containing esomeprazole magnesium trihydrate ... Each capsule contains 20 or 40 mg of esomeprazole present as 22.3 or 44.5 mg of esomeprazole magnesium trihydrate. ... Esomeprazole is marketed under the trade name Nexium (AstraZeneca).、Table: Esomeprazole Magnesium Preparations [Table#8119]、Table: Esomeprazole Magnesium Combination Preparations [Table#8120]、Table: Esomeprazole Sodium Preparations [Table#8121]。
埃索美拉唑（CAS 119141-88-7）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 119141-88-7 |
|---|---|
| PubChem CID | 9568614 |
| Molecular formula | C17H19N3O3S |
| IUPAC name | 6-methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]-1H-benzimidazole |
| UNII (FDA) | N3PA6559FT |
| Molecular Weight | 345.4 |
|---|---|
| XLogP3 | 2.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 345.11471265 |
| Monoisotopic Mass | 345.11471265 |
| Topological Polar Surface Area | 96.3 |
| Heavy Atom Count | 24 |
| Melting Point | 155 |
|---|---|
| LogP | 0.6 |
Esomeprazole; 119141-88-7; (S)-Omeprazole; (-)-Omeprazole; Inexium paranova; (S)-(-)-Omeprazole; esomeprazol; esomeprazolum; Alenia; Esofag; Escz; Nexiam; Omeprazole, (s)-; Perprazole; Esopral; Axagon
| Reported hazard statements | H312 (100%), H315 (100%), H317 (100%), H319 (100%), H335 (100%), H412 (100%) |
|---|
H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Esomeprazole · CAS 119141-88-7 · C17H19N3O3S. UNII N3PA6559FT. Melting Point: 155; LogP: 0.6.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Esomeprazole