Eprosartan

Description

Eprosartan · CAS 133040-01-4 · C23H24N2O4S. UNII 2KH13Z0S0Y. Melting Point: 248-250 °C (mesylate form); Melting Point: 260-261 °C; Melting Point: 248 - 250 °C (mesylate form).

Identification

CAS Registry Number	133040-01-4
PubChem CID	5281037
Molecular formula	C23H24N2O4S
IUPAC name	4-[[2-butyl-5-[(E)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]benzoic acid
UNII (FDA)	2KH13Z0S0Y

Computed Descriptors

Molecular Weight	424.5
XLogP3	4.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	10
Exact Mass	424.14567842
Monoisotopic Mass	424.14567842
Topological Polar Surface Area	121
Heavy Atom Count	30
Formal Charge	0

Physical & Chemical Properties

Melting Point	248-250 °C (mesylate form)
Melting Point	260-261 °C
Melting Point	248 - 250 °C (mesylate form)
Solubility	8.66e-03 g/L
LogP	3.9

Physical description & handling notes

• Solid
• Crystals from methanol
• Insoluble (mesylate form)
• Stable under recommended storage conditions.
• Hazardous decomposition products: Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx), Sulphur oxides.
• White to off-white crystalline powder, mp 248-250 °C. Insoluble in water. Freely soluble in ethanol /Eprosartan monomethanesulfonate/

GHS Hazard Classification

Reported hazard statements	H315, H319

Documented Uses

• Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents
• Use (kg) in Switzerland (2009): >1000
• Use (kg; approx.) in Germany (2009): >25000
• Use (kg; exact) in Germany (2009): 33702
• Consumption (g per capita) in Switzerland (2009): 0.13
• Consumption (g per capita; approx.) in Germany (2009): 0.31

Synonyms

Eprosartan; 133040-01-4; SK&F 108566; SK&F-108566; SKF-108566; 2KH13Z0S0Y; (E)-2-Butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic acid; CHEBI:4814; SK-108566; DTXSID0022989; (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid; (E)-alpha{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid; 2-Thiophenepropanoic acid, alpha-((2-butyl-1-((4-carboxyphenyl)methyl)-lH-imidazol-5-yl)methylene)-, (E)-; 4-[[2-butyl-5-[(E)-3-hydroxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-enyl]imidazol-1-yl]methyl]benzoic acid; 4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid; Eprosartanum

Frequently Asked Questions

What are the CAS number and molecular formula of Eprosartan?

CAS 133040-01-4; molecular formula C23H24N2O4S; molecular weight — g/mol.

What other names is Eprosartan known by?

Eprosartan, 133040-01-4, SK&F 108566, SK&F-108566, SKF-108566, 2KH13Z0S0Y.

Is Eprosartan classified as hazardous?

Hazard statements reported: H315, H319.

What are the key physical properties of Eprosartan?

Melting Point: 248-250 °C (mesylate form); Melting Point: 260-261 °C; Melting Point: 248 - 250 °C (mesylate form); Solubility: 8.66e-03 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.