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恩夫韦肽

CAS 159519-65-0C204H301N51O64MW 4492

恩夫韦肽(CAS 159519-65-0):分子式 C204H301N51O64、分子量 4492。

产品概览

CAS号159519-65-0
分子式C204H301N51O64
分子量4492
LogP-14.7
应用领域Uses: Medication、Antiviral (systemic)、Methods of Manufacturing: Preparation ... D.P. Bolognesi et al、WO 94 28920、eidem、US 5464933 (1994、1995 both to Duke University)、Formulations、Preparations: Parenteral: For injection: 108 mg Fuzeon (with sterile water for injection diluent)、(Roche).、General Manufacturing Information: Whilte data specific to enfuvirtide were not located(SRC、2005)、the literature suggests that some pharmaceutically active compounds originating from human and veterinary therapy are not eliminated completely in municipal sewage treatment plants and are therefore discharged into receiving waters(1). Wastewater treatment processes often were not designed to remove them from the effluent(2). Selected organic waste compounds may be degrading to new and more persistent compounds that may be released instead of or in addition to the parent compound(2). Studies have indicated that several polar pharmaceutically active compounds can leach through subsoils into aquifers(1).

应用领域

登记用途:Uses: Medication、Antiviral (systemic)、Methods of Manufacturing: Preparation ... D.P. Bolognesi et al、WO 94 28920、eidem、US 5464933 (1994、1995 both to Duke University)、Formulations、Preparations: Parenteral: For injection: 108 mg Fuzeon (with sterile water for injection diluent)、(Roche).、General Manufacturing Information: Whilte data specific to enfuvirtide were not located(SRC、2005)、the literature suggests that some pharmaceutically active compounds originating from human and veterinary therapy are not eliminated completely in municipal sewage treatment plants and are therefore discharged into receiving waters(1). Wastewater treatment processes often were not designed to remove them from the effluent(2). Selected organic waste compounds may be degrading to new and more persistent compounds that may be released instead of or in addition to the parent compound(2). Studies have indicated that several polar pharmaceutically active compounds can leach through subsoils into aquifers(1).。

技术档案

这个产品是什么

恩夫韦肽 是一种化工化合物,登记 CAS 号为 159519-65-0,分子式 C204H301N51O64(分子量 4492)。

识别信息

登记 CAS 号:159519-65-0

其分子式 C204H301N51O64 由 204 个碳、301 个氢、51 个氮、64 个氧 组成。

别名/同义词:恩夫韦肽 · Enfuvirtide

常见问题

恩夫韦肽 的 CAS 号是多少?

恩夫韦肽 的 CAS 登记号为 159519-65-0。

恩夫韦肽 的分子式与分子量是多少?

分子式 C204H301N51O64,分子量 4492。

恩夫韦肽 还有哪些别名?

别名/同义词:恩夫韦肽、Enfuvirtide。

恩夫韦肽 的登记用途是什么?

登记用途:Uses: Medication、Antiviral (systemic)、Methods of Manufacturing: Preparation ... D.P. Bolognesi et al、WO 94 28920、eidem、US 5464933 (1994、1995 both to Duke University)、Formulations、Preparations: Parenteral: For injection: 108 mg Fuzeon (with sterile water for injection diluent)、(Roche).、General Manufacturing Information: Whilte data specific to enfuvirtide were not located(SRC、2005)、the literature suggests that some pharmaceutically active compounds originating from human and veterinary therapy are not eliminated completely in municipal sewage treatment plants and are therefore discharged into receiving waters(1). Wastewater treatment processes often were not designed to remove them from the effluent(2). Selected organic waste compounds may be degrading to new and more persistent compounds that may be released instead of or in addition to the parent compound(2). Studies have indicated that several polar pharmaceutically active compounds can leach through subsoils into aquifers(1).。

PubChem 公开数据

恩夫韦肽(CAS 159519-65-0)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number159519-65-0
PubChem CID16130199
Molecular formulaC204H301N51O64
UNII (FDA)19OWO1T3ZE

计算分子描述符

Molecular Weight4492
XLogP3-14.7
Hydrogen Bond Donor Count63
Hydrogen Bond Acceptor Count67
Rotatable Bond Count151
Exact Mass4491.1933541
Monoisotopic Mass4489.1866445
Topological Polar Surface Area1900
Heavy Atom Count319

在册的理化数值

Hydrophobicity-0.875

在册的记载用途

    Preparation ... D.P. Bolognesi et al, WO 94 28920; eidem, US 5464933 (1994, 1995 both to Duke University)Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.

    同义词与商品名

    Enfuvirtide; Pentafuside; Fuzeon; DP178; DP-178; Enfuvirtida; CHEBI:608828; Fuzeon T-20; 19OWO1T3ZE; DTXSID20166672; peptide T20; T20, Peptide; enfuvirtidum; RefChem:55093; DTXCID8089163; J05AX07

    GHS 危害分类

    Reported hazard statementsH317 (100%)

    H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

    P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement)

    公开数据库对它的描述

    Enfuvirtide · CAS 159519-65-0 · C204H301N51O64. UNII 19OWO1T3ZE. Hydrophobicity: -0.875.

    物理形态与操作说明

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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