EDTA二钠盐二水合物（CAS 6381-92-6）：分子式 C10H16N2O8、分子量 292.24。
| CAS号 | 6381-92-6 |
|---|---|
| 分子式 | C10H16N2O8 |
| 分子量 | 292.24 |
| 熔点 | 237 |
| LogP | -2.6 |
| 应用领域 | Uses: CIR ingredient: Disodium EDTA、CIR ingredient: EDTA、Used in chemical analysis and to make detergents、[CAMEO] Used therapeutically as a metal chelating agent、Also used as a food preservative、blood anticoagulant、and a chelating agent in personal care products and in the pulp and paper industry、[Merck Index、3517] Used therapeutically to remove (chelate) metal ions in the body、[HSDB] Used in photography (color developing baths) and holography、[www.ci.tucson.az.us、arthazards、medium.html]、Pulp and Paper Processing [Category: Industry]、Photographic Processing [Category: Other]、Formerly registered in the US for use as a disinfectant and component of contact lens solutions、[NPIRS] Used as a preservative、color retention agent、antioxidant、flavoring agent for foods、anticoagulant for blood collection、and chelating agent in personal care products、Also used in the pulp and paper industry、in laboratory titrimetric analysis of metals、and as a therapeutic chelating agent、[Merck Index] Used in the agricultural、paper-pulp-board、textile processing、detergent、and cosmetics industries、Used as a cleaning、washing agent、disinfectant、coloring agent、complexing agent、stabilizer、and micro-nutrient、[IUCLID]、Using Disinfectants or Biocides [Category: Clean]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、For ethylenediaminetetraacetic acid (USEPA、OPP Pesticide Code: 039101) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、The active ingredient is no longer contained in any registered、pesticide、products ... "cancelled."、As antioxidant in foods、Chelating agent in boiler and cooling water、detergents for household and textile use、industrial germicides、and metal cutting fluids、chemical intermediate for micronutrients for agricultural purposes、bleaching agent in color film processing、chelating agent in electroless nickel plating、etching agent in metal finishing and semiconductor production、chelating agent in wood pulping processes、activator in butadiene-styrene copolymerization、chelating agent in food、pharmaceuticals and cosmetics and for gas scrubbing、component of blood anticoagulants、For more Uses (Complete) data for ETHYLENEDIAMINE TETRAACETIC ACID (13 total)、please visit the HSDB record page.、For disodium EDTA (USEPA、OPP Pesticide Code: 039115) there are 0 labels match.、The active ingredient is no longer contained in any registered products ... "cancelled."、Disodium EDTA is a preservative、sequestrant、and stabilizer ... Disodium EDTA is permitted in the feed and drinking water of animals and、or for the treatment of food-producing animals. ... Disodium EDTA is not expected to contain preservatives、antioxidants、or sequestering agents for the purposes of stabilization.、Prevent discoloration due to trace metals in antibiotics、antihistamines、and local anesthetics. They are used to stabilize solutions of ascorbic acid (vitamin C)、hydrogen peroxide、formaldehyde、folic acid、and hyaluronidase and are used to increase antibacterial activity of components of ophthalmic and contact lens care solutions.、For more Uses (Complete) data for Disodium EDTA (7 total)、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 92.1、For the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy、in both pediatric populations and adults.、Use Classification: Fragrance Ingredients、Food Additives -> ANTIOXIDANT_SYNERGIST、PRESERVATIVE、SEQUESTRANT、SYNERGIST -> JECFA Functional Classes、Cosmetics -> Viscosity controlling、Chelating、Adjuvants、Industry Uses: CBI、Chelating agent、Ion exchange agent、Binder、Processing aids not otherwise specified、Cleaning agent、Not Known or Reasonably Ascertainable、Soil amendments (fertilizers)、Oxidizing agent、Consumer Uses: Chelating agent、Household Products: Information on 389 consumer products that contain Ethylenediaminetetraacetic acid (EDTA) in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Home Maintenance、• Inside the Home、• Personal Care、• Pet Care、Information on 1150 consumer products that contain Disodium EDTA in the following categories is provided:、Methods of Manufacturing: EDTA ...、is、formed when ethylenediamine was condensed with sodium monochloroacetate in the presence of sodium carbonate. An aqueous solution of the reactants was heated to 90 °C for 10 hours、then was cooled and acidified with hydrochloric acid、where upon the acid precipitated.、All of the industrially used methods of manufacture of EDTA and its salts involve the addition of formaldehyde and hydrogen cyanide or an alkali metal cyanide to an aqueous solution of EDTA. The salts、or edetates、are then formed by hydrolysis. EDTA can also be formed by heating tetrahydroxyethylethylenediamine with sodium or potassium hydroxide using a cadmium oxide catalyst.、The most widely used synthesis is the alkaline cyanomethylation of ethylenediamine by means of sodium cyanide and formaldehyde. ... This method offers high yields (>90%) of the chelating agent. The principal byproduct is am |
登记用途：Uses: CIR ingredient: Disodium EDTA、CIR ingredient: EDTA、Used in chemical analysis and to make detergents、[CAMEO] Used therapeutically as a metal chelating agent、Also used as a food preservative、blood anticoagulant、and a chelating agent in personal care products and in the pulp and paper industry、[Merck Index、3517] Used therapeutically to remove (chelate) metal ions in the body、[HSDB] Used in photography (color developing baths) and holography、[www.ci.tucson.az.us、arthazards、medium.html]、Pulp and Paper Processing [Category: Industry]、Photographic Processing [Category: Other]、Formerly registered in the US for use as a disinfectant and component of contact lens solutions、[NPIRS] Used as a preservative、color retention agent、antioxidant、flavoring agent for foods、anticoagulant for blood collection、and chelating agent in personal care products、Also used in the pulp and paper industry、in laboratory titrimetric analysis of metals、and as a therapeutic chelating agent、[Merck Index] Used in the agricultural、paper-pulp-board、textile processing、detergent、and cosmetics industries、Used as a cleaning、washing agent、disinfectant、coloring agent、complexing agent、stabilizer、and micro-nutrient、[IUCLID]、Using Disinfectants or Biocides [Category: Clean]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、For ethylenediaminetetraacetic acid (USEPA、OPP Pesticide Code: 039101) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、The active ingredient is no longer contained in any registered、pesticide、products ... "cancelled."、As antioxidant in foods、Chelating agent in boiler and cooling water、detergents for household and textile use、industrial germicides、and metal cutting fluids、chemical intermediate for micronutrients for agricultural purposes、bleaching agent in color film processing、chelating agent in electroless nickel plating、etching agent in metal finishing and semiconductor production、chelating agent in wood pulping processes、activator in butadiene-styrene copolymerization、chelating agent in food、pharmaceuticals and cosmetics and for gas scrubbing、component of blood anticoagulants、For more Uses (Complete) data for ETHYLENEDIAMINE TETRAACETIC ACID (13 total)、please visit the HSDB record page.、For disodium EDTA (USEPA、OPP Pesticide Code: 039115) there are 0 labels match.、The active ingredient is no longer contained in any registered products ... "cancelled."、Disodium EDTA is a preservative、sequestrant、and stabilizer ... Disodium EDTA is permitted in the feed and drinking water of animals and、or for the treatment of food-producing animals. ... Disodium EDTA is not expected to contain preservatives、antioxidants、or sequestering agents for the purposes of stabilization.、Prevent discoloration due to trace metals in antibiotics、antihistamines、and local anesthetics. They are used to stabilize solutions of ascorbic acid (vitamin C)、hydrogen peroxide、formaldehyde、folic acid、and hyaluronidase and are used to increase antibacterial activity of components of ophthalmic and contact lens care solutions.、For more Uses (Complete) data for Disodium EDTA (7 total)、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 92.1、For the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy、in both pediatric populations and adults.、Use Classification: Fragrance Ingredients、Food Additives -> ANTIOXIDANT_SYNERGIST、PRESERVATIVE、SEQUESTRANT、SYNERGIST -> JECFA Functional Classes、Cosmetics -> Viscosity controlling、Chelating、Adjuvants、Industry Uses: CBI、Chelating agent、Ion exchange agent、Binder、Processing aids not otherwise specified、Cleaning agent、Not Known or Reasonably Ascertainable、Soil amendments (fertilizers)、Oxidizing agent、Consumer Uses: Chelating agent、Household Products: Information on 389 consumer products that contain Ethylenediaminetetraacetic acid (EDTA) in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Home Maintenance、• Inside the Home、• Personal Care、• Pet Care、Information on 1150 consumer products that contain Disodium EDTA in the following categories is provided:、Methods of Manufacturing: EDTA ...、is、formed when ethylenediamine was condensed with sodium monochloroacetate in the presence of sodium carbonate. An aqueous solution of the reactants was heated to 90 °C for 10 hours、then was cooled and acidified with hydrochloric acid、where upon the acid precipitated.、All of the industrially used methods of manufacture of EDTA and its salts involve the addition of formaldehyde and hydrogen cyanide or an alkali metal cyanide to an aqueous solution of EDTA. The salts、or edetates、are then formed by hydrolysis. EDTA can also be formed by heating tetrahydroxyethylethylenediamine with sodium or potassium hydroxide using a cadmium oxide catalyst.、The most widely used synthesis is the alkaline cyanomethylation of ethylenediamine by means of sodium cyanide and formaldehyde. ... This method offers high yields (>90%) of the chelating agent. The principal byproduct is am。
EDTA二钠盐二水合物 是一种化工化合物，登记 CAS 号为 6381-92-6，分子式 C10H16N2O8（分子量 292.24）。
登记 CAS 号：6381-92-6
其分子式 C10H16N2O8 由 10 个碳、16 个氢、2 个氮、8 个氧 组成。
别名/同义词：EDTA二钠盐二水合物 · EDTA disodium salt dihydrate
EDTA二钠盐二水合物 的 CAS 登记号为 6381-92-6。
分子式 C10H16N2O8，分子量 292.24。
别名/同义词：EDTA二钠盐二水合物、EDTA disodium salt dihydrate。
登记用途：Uses: CIR ingredient: Disodium EDTA、CIR ingredient: EDTA、Used in chemical analysis and to make detergents、[CAMEO] Used therapeutically as a metal chelating agent、Also used as a food preservative、blood anticoagulant、and a chelating agent in personal care products and in the pulp and paper industry、[Merck Index、3517] Used therapeutically to remove (chelate) metal ions in the body、[HSDB] Used in photography (color developing baths) and holography、[www.ci.tucson.az.us、arthazards、medium.html]、Pulp and Paper Processing [Category: Industry]、Photographic Processing [Category: Other]、Formerly registered in the US for use as a disinfectant and component of contact lens solutions、[NPIRS] Used as a preservative、color retention agent、antioxidant、flavoring agent for foods、anticoagulant for blood collection、and chelating agent in personal care products、Also used in the pulp and paper industry、in laboratory titrimetric analysis of metals、and as a therapeutic chelating agent、[Merck Index] Used in the agricultural、paper-pulp-board、textile processing、detergent、and cosmetics industries、Used as a cleaning、washing agent、disinfectant、coloring agent、complexing agent、stabilizer、and micro-nutrient、[IUCLID]、Using Disinfectants or Biocides [Category: Clean]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、For ethylenediaminetetraacetic acid (USEPA、OPP Pesticide Code: 039101) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、The active ingredient is no longer contained in any registered、pesticide、products ... "cancelled."、As antioxidant in foods、Chelating agent in boiler and cooling water、detergents for household and textile use、industrial germicides、and metal cutting fluids、chemical intermediate for micronutrients for agricultural purposes、bleaching agent in color film processing、chelating agent in electroless nickel plating、etching agent in metal finishing and semiconductor production、chelating agent in wood pulping processes、activator in butadiene-styrene copolymerization、chelating agent in food、pharmaceuticals and cosmetics and for gas scrubbing、component of blood anticoagulants、For more Uses (Complete) data for ETHYLENEDIAMINE TETRAACETIC ACID (13 total)、please visit the HSDB record page.、For disodium EDTA (USEPA、OPP Pesticide Code: 039115) there are 0 labels match.、The active ingredient is no longer contained in any registered products ... "cancelled."、Disodium EDTA is a preservative、sequestrant、and stabilizer ... Disodium EDTA is permitted in the feed and drinking water of animals and、or for the treatment of food-producing animals. ... Disodium EDTA is not expected to contain preservatives、antioxidants、or sequestering agents for the purposes of stabilization.、Prevent discoloration due to trace metals in antibiotics、antihistamines、and local anesthetics. They are used to stabilize solutions of ascorbic acid (vitamin C)、hydrogen peroxide、formaldehyde、folic acid、and hyaluronidase and are used to increase antibacterial activity of components of ophthalmic and contact lens care solutions.、For more Uses (Complete) data for Disodium EDTA (7 total)、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 92.1、For the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy、in both pediatric populations and adults.、Use Classification: Fragrance Ingredients、Food Additives -> ANTIOXIDANT_SYNERGIST、PRESERVATIVE、SEQUESTRANT、SYNERGIST -> JECFA Functional Classes、Cosmetics -> Viscosity controlling、Chelating、Adjuvants、Industry Uses: CBI、Chelating agent、Ion exchange agent、Binder、Processing aids not otherwise specified、Cleaning agent、Not Known or Reasonably Ascertainable、Soil amendments (fertilizers)、Oxidizing agent、Consumer Uses: Chelating agent、Household Products: Information on 389 consumer products that contain Ethylenediaminetetraacetic acid (EDTA) in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Home Maintenance、• Inside the Home、• Personal Care、• Pet Care、Information on 1150 consumer products that contain Disodium EDTA in the following categories is provided:、Methods of Manufacturing: EDTA ...、is、formed when ethylenediamine was condensed with sodium monochloroacetate in the presence of sodium carbonate. An aqueous solution of the reactants was heated to 90 °C for 10 hours、then was cooled and acidified with hydrochloric acid、where upon the acid precipitated.、All of the industrially used methods of manufacture of EDTA and its salts involve the addition of formaldehyde and hydrogen cyanide or an alkali metal cyanide to an aqueous solution of EDTA. The salts、or edetates、are then formed by hydrolysis. EDTA can also be formed by heating tetrahydroxyethylethylenediamine with sodium or potassium hydroxide using a cadmium oxide catalyst.、The most widely used synthesis is the alkaline cyanomethylation of ethylenediamine by means of sodium cyanide and formaldehyde. ... This method offers high yields (>90%) of the chelating agent. The principal byproduct is am。
EDTA二钠盐二水合物（CAS 6381-92-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 6381-92-6 |
|---|---|
| PubChem CID | 6049 |
| Molecular formula | C10H16N2O8 |
| IUPAC name | 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid |
| UNII (FDA) | 9G34HU7RV0 |
| Molecular Weight | 292.24 |
|---|---|
| XLogP3 | -5.9 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 11 |
| Exact Mass | 292.09066547 |
| Monoisotopic Mass | 292.09066547 |
| Topological Polar Surface Area | 156 |
| Heavy Atom Count | 20 |
| Melting Point | 237 |
|---|---|
| Melting Point | 245 °C |
| Solubility | 1000000 |
| Solubility | In water, 1,000 mg/L at 25 °C |
| Solubility | 9.26e+00 g/L |
| LogP | -2.6 |
| Decomposition | 220-245 °C |
| Dissociation Constants | pKa = 0.26 |
| Other Experimental Properties | Decomposition at 240 °C |
| Color Additive Status | 73.1 |
EDTA; Ethylenediaminetetraacetic acid; Edetic acid; 60-00-4; Edathamil; Sequestrol; Havidote; Titriplex; Cheelox; EDTA acid; Sequestrene aa; Versene acid; Trilon BS; Gluma cleanser; Sequestric acid; Warkeelate acid
| Regulatory & Food Contact | FDA Regulatory Status of Color Additives: Foods, Drugs FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS ANTIOXIDANT_SYNERGIST; PRESERVATIVE; SEQUESTRANT; SYNERGIST: Food Additives EDTA, DISODIUM |
|---|---|
| GHS notification summary | 0.4% (6 / 1452) |
| GHS notification summary | 0.4% (6 / 1452) |
|---|---|
| Reported hazard statements | H319, H332 (24.5%), H373 (23.5%), H302 (43.8%), H312 (26.9%), H315 (32.5%), H335 (31.8%), H412 (30.2%) |
H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
EDTA disodium salt dihydrate · CAS 6381-92-6 · C10H16N2O8. UNII 9G34HU7RV0. Melting Point: 237; Melting Point: 245 °C; Solubility: 1000000.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: EDTA disodium salt dihydrate