Econazole

CAS 27220-47-9C18H15Cl3N2OMW 381.7

Econazole (CAS 27220-47-9) — formula C18H15Cl3N2O, molecular weight 381.7.

Product Overview

CAS Number	27220-47-9
Molecular Formula	C18H15Cl3N2O
Molecular Weight	381.7
Melting Point	162
LogP	5.5
Applications	Uses: Use (kg, approx.) in Germany (2009): >100, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Calculated removal (%): 93.8, For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by <i>Trichophyton rubrum<, i>, <i>Trichophyton mentagrophytes<, <i>Trichophyton tonsurans<, <i>Microsporum canis<, <i>Microsporum audouini<, <i>Microsporum gypseum<, and <i>Epidermophyton floccosum<, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.

Applications

Documented applications: Uses: Use (kg, approx.) in Germany (2009): >100, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Calculated removal (%): 93.8, For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum<, i>, Trichophyton mentagrophytes<, Trichophyton tonsurans<, Microsporum canis<, Microsporum audouini<, Microsporum gypseum<, and Epidermophyton floccosum<, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor..

Technical Profile

What this product is

Econazole is a chemical compound with CAS registry number 27220-47-9 and molecular formula C18H15Cl3N2O (molecular weight 381.7).

Identification

CAS number: 27220-47-9

Its molecular formula C18H15Cl3N2O comprises 18 C, 15 H, 3 Cl, 2 N, 1 O atoms.

Also known as: Econazole · 益康唑

Frequently Asked Questions

What is the CAS number of Econazole?

The CAS registry number of Econazole is 27220-47-9.

What is the molecular formula and molecular weight of Econazole?

Molecular formula C18H15Cl3N2O, molecular weight 381.7.

What other names is Econazole known by?

It is also registered under: Econazole, 益康唑.

What are the documented applications of Econazole?

Recorded applications: Uses: Use (kg, approx.) in Germany (2009): >100, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Calculated removal (%): 93.8, For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum<, i>, Trichophyton mentagrophytes<, Trichophyton tonsurans<, Microsporum canis<, Microsporum audouini<, Microsporum gypseum<, and Epidermophyton floccosum<, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor..

PubChem Public Data

Independent reference data for Econazole (CAS 27220-47-9), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	27220-47-9
PubChem CID	3198
Molecular formula	C18H15Cl3N2O
IUPAC name	1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
UNII (FDA)	6Z1Y2V4A7M

Computed descriptors

Molecular Weight	381.7
XLogP3	5.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	380.024996
Monoisotopic Mass	380.024996
Topological Polar Surface Area	27.1
Heavy Atom Count	24

Physicochemical values on record

Melting Point	162
Solubility	1.48e-03 g/L
LogP	5.5

Documented uses on record

Synonyms and trade names

econazole; 27220-47-9; Econazolum; Econazol; (+-)-Econazole; 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; 1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; NSC-187789; 6Z1Y2V4A7M; DTXSID2029872; 1-{2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; 1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole; 1H-Imidazole, 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-; Imidazole, 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-; 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-; econazolo

Regulatory listings held on file

GHS notification summary	2.6% (1 / 39)

GHS hazard classification

GHS notification summary	2.6% (1 / 39)
Reported hazard statements	H302 (97.4%)

This chemical does not meet GHS hazard criteria for 2.6% (1 of 39) of reports.

H302 (97.4%): Harmful if swallowed [Warning Acute toxicity, oral]

What the public record says

Econazole · CAS 27220-47-9 · C18H15Cl3N2O. UNII 6Z1Y2V4A7M. Melting Point: 162; Solubility: 1.48e-03 g/L; LogP: 5.5.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.