Doramectin

Description

Doramectin · CAS 117704-25-3 · C50H74O14. UNII KGD7A54H5P. Melting Point: 116-119 °C; Collision Cross Section: 308.14 Ų [M+Na]+.

Identification

CAS Registry Number	117704-25-3
PubChem CID	9832750
Molecular formula	C50H74O14
UNII (FDA)	KGD7A54H5P

Computed Descriptors

Molecular Weight	899.1
XLogP3	4.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	7
Exact Mass	898.50785703
Monoisotopic Mass	898.50785703
Topological Polar Surface Area	170
Heavy Atom Count	64
Formal Charge	0

Physical & Chemical Properties

Melting Point	116-119 °C
Collision Cross Section	308.14 Ų [M+Na]+

Regulatory Status

Regulatory & Food Contact	ANTHELMINTHIC_AGENT: Veterinary Drug JECFA ADI: 0-0.001 mg/kg bw TRS 925-JECFA 62/15 FAS 49-JECFA 58/3 (2002)

GHS Hazard Classification

Reported hazard statements	H300 (33.3%), H301 (36.9%), H302 (29.7%), H360 (31.5%), H361 (30.6%), H362 (31.5%), H370 (33.3%), H372 (31.5%)

Documented Uses

• Therap cat (vet): antiparasitic
• ... Control of certain gastrointestinal roundworms, lungworms, eyeworms, kidney worms, grubs, lice, and mange mites (in cattle and swine)[US FDA; Animal Drugs, Feeds, and Related Products: Doramectin. Federal Register: November 21, 1997 (Volume 62, Number 225)] [Rules and Regulations]
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Veterinary Drug -> ANTHELMINTHIC_AGENT -> JECFA Functional Classes
• ... S.P. Gibson et al., European patent 214,731; /corresponds to/ US patent 5,089,480 (1987, 1992 both to Pfizer).
• ... Fermentation product of a specific strain of Streptomyces avermitilis ... .

Synonyms

Doramectin; 117704-25-3; Doramectina; Dectomax; Doramectine; Doramectinum; DTXSID9048982; UK 67994; UK-67994; UK-67,994; KGD7A54H5P; NSC-760342; Avermectin A1a, 25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)-; L-701023; DTXCID5028908; L 701023

Frequently Asked Questions

What are the CAS number and molecular formula of Doramectin?

CAS 117704-25-3; molecular formula C50H74O14; molecular weight — g/mol.

What other names is Doramectin known by?

Doramectin, 117704-25-3, Doramectina, Dectomax, Doramectine, Doramectinum.

What is the regulatory status of Doramectin?

Documented regulatory listings: ANTHELMINTHIC_AGENT: Veterinary Drug; JECFA ADI: 0-0.001 mg/kg bw; TRS 925-JECFA 62/15.

Is Doramectin classified as hazardous?

Hazard statements reported: H300, H301, H302, H360, H361.

What are the key physical properties of Doramectin?

Melting Point: 116-119 °C; Collision Cross Section: 308.14 Ų [M+Na]+.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.