多替拉韦

多替拉韦（CAS 1051375-16-6）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

计算分子描述符

在册的理化数值

在册的记载用途

Preparation: B. A. Johns et al., World Intellectual Property Organization patent 06116764 (2006 to Shionogi); eidem, United States of America patent 090318421 (2009)Dolutegravir is a human immunodeficiency virus (HIV) integrase inhibitor, the third in this class of agents that target the viral integrase. Dolutegravir is used only in combination with other antiretroviral agents in the treatment of HIV infection, and it has had limited use. Dolutegravir is associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of acute, clinically apparent liver injury.

同义词与商品名

Dolutegravir; 1051375-16-6; GSK1349572; S/GSK1349572; GSK 1349572; GSK-1349572; S-349572; DKO1W9H7M1; CHEBI:76010; DTXSID90909356; dolutegravirum; RefChem:56964; J05AX12; DTXCID701338419; Tivicay; Dolutegravir (GSK1349572)

已收录的法规名录

GHS notification summary	33.3% (1 / 3)

GHS 危害分类

GHS notification summary	33.3% (1 / 3)
Reported hazard statements	H400 (66.7%), H410 (66.7%)

This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.

H400 (66.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

公开数据库对它的描述

Dolutegravir · CAS 1051375-16-6 · C20H19F2N3O5. UNII DKO1W9H7M1. Melting Point: 190-193ºC; LogP: 2.2; Dissociation Constants: 8.2.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。