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DOCETAXEL

CAS 114977-28-5C43H53NO14MW 807.9

DOCETAXEL (CAS No. 114977-28-5) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number114977-28-5
Molecular FormulaC43H53NO14
Molecular Weight807.9
Melting Point232
LogP2.4
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Applications

Pharmaceutical Intermediates & APIs

Packaging & Storage

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Product Profile

Product Overview

DOCETAXEL is a pharmaceutical intermediate or API compound with CAS registry number 114977-28-5 and molecular formula C43H53NO14 (molecular weight 807.9), belonging to the 医药中间体及原料药 segment of chemical raw materials.

Pharmaceutical intermediates and APIs are critical building blocks for drug synthesis, with strict requirements on purity, impurities and process consistency.

DOCETAXEL is typically applied in Pharmaceutical Intermediates &amp, APIs.

Jinan Shenghe Chemical Co., Ltd. supplies DOCETAXEL with stable inventory and provides a Certificate of Analysis (COA) with each batch; custom repacking is available per process requirement.

Chemical Identity & Nomenclature

CAS number: 114977-28-5 — searchable in PubChem for physicochemical, safety and regulatory data.

Its molecular formula C43H53NO14 comprises 43 C, 53 H, 1 N, 14 O atoms.

Also known as: DOCETAXEL

Category: 医药中间体及原料药

Applications & Use Cases

Used in API synthesis, formulation and pre-clinical research; supplied with COA and impurity-profile documentation.

In the Pharmaceutical Intermediates &amp field, DOCETAXEL is selected for its consistent quality and documented specifications. In the APIs field, DOCETAXEL is selected for its consistent quality and documented specifications.

Specifications & Quality

Typical purity is 按批次COA提供(不公开发布). Packaging is 按订单/批次确认(不公开发布). Storage: sealed, in a cool and dry place. Each batch ships with a COA; MSDS and other technical documents are available on request.

Sourcing & Support

Supplier: Jinan Shenghe Chemical Co., Ltd.. Samples can be arranged on request; lead time depends on stock and order size. Quotes are returned within one business day by email or WhatsApp.

Email: info@591daili.com · Tel/WhatsApp: +86-18553102138

Frequently Asked Questions

What is the CAS number of DOCETAXEL?

The CAS number of DOCETAXEL is 114977-28-5.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of DOCETAXEL?

Main applications include Pharmaceutical Intermediates & APIs.

What quality documents are provided?

Each batch ships with a Certificate of Analysis (COA). MSDS and other technical documents are available on request.

How should DOCETAXEL be stored and handled?

Store sealed in a cool, dry place. Handling and PPE follow the MSDS supplied with the batch; general chemical-handling precautions are recommended.

Can I request a sample?

Samples are available on request. Please contact us at info@591daili.com or via WhatsApp for details.

How do I buy DOCETAXEL or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Docetaxel Anhydrous · CAS 114977-28-5 · C43H53NO14. UNII 699121PHCA. Melting Point: 232; Melting Point: 232 °C; Solubility: 1.27e-02 g/L.

Identification

CAS Registry Number114977-28-5
PubChem CID148124
Molecular formulaC43H53NO14
IUPAC name[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
UNII (FDA)699121PHCA

Computed Descriptors

Molecular Weight807.9
XLogP31.6
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count14
Rotatable Bond Count13
Exact Mass807.34660536
Monoisotopic Mass807.34660536
Topological Polar Surface Area224
Heavy Atom Count58
Formal Charge0

Physical & Chemical Properties

Melting Point232
Melting Point232 °C
Solubility1.27e-02 g/L
LogP2.4
LogP3.4

Physical description & handling notes

  • Solid
  • Insoluble
  • Specific optical rotation: - 36 deg (c = 0.74 in ethanol)
  • White to almost white powder. Highly lipophilic. Practically insoluble in water /Docetaxel trihydrate/
  • Table: Docetaxel Preparations [Table#6526]

GHS Hazard Classification

Reported hazard statementsH315 (14.3%), H319 (64.3%), H341 (85.7%), H351 (21.4%), H360 (35.7%), H361 (42.9%), H362 (35.7%), H372 (57.1%)

H315 (14.3%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (64.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Documented Uses

  • Antineoplastic Agents; Tubulin Modulators
  • Use (kg; approx.) in Germany (2009): >10
  • Consumption (g per capita; approx.) in Germany (2009): 0.000122
  • Consumption (g per capita) in the USA (2002): 4.32e-05
  • Semisynthetic derivative of paclitaxel, q.v., prepared using a natural precursor, 10-deacetylbaccatin III, extracted from the needles of the European yew tree, Taxus baccata L., Taxaceae.
  • Preparation: M. Colins et al., European Patent Office patent 253738; eidem, United States of America patent 4814470 (1988, 1989 both to Rhone-Poulenc Sante);

Synonyms

docetaxel; 114977-28-5; Taxotere; Docetaxel anhydrous; Docetaxel Kabi; Docetaxel Winthrop; Docefrez; DOCETAXEL MYLAN; RP-56976; NSC-628503; DTXSID0040464; Docetaxel Teva; Docetaxel Accord; DOCETAXEL TEVA PHARMA; BEIZRAY; BIND 014

Frequently Asked Questions

What are the CAS number and molecular formula of Docetaxel Anhydrous?

CAS 114977-28-5; molecular formula C43H53NO14; molecular weight — g/mol.

What other names is Docetaxel Anhydrous known by?

docetaxel, 114977-28-5, Taxotere, Docetaxel anhydrous, Docetaxel Kabi, Docetaxel Winthrop.

Is Docetaxel Anhydrous classified as hazardous?

Hazard statements reported: H315, H319, H341, H351, H360.

What are the key physical properties of Docetaxel Anhydrous?

Melting Point: 232; Melting Point: 232 °C; Solubility: 1.27e-02 g/L; LogP: 2.4.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

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