disopyramide free base

Independent reference data for disopyramide free base (CAS 3737-09-5), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias. It is a Class Ia antiarrhythmic drug.Disopyramide, a class 1A antiarrhythmic drug, received Food and Drug Administration approval on September 29, 1978, for established ventricular arrhythmias like sustained ventricular tachycardia that, in the physician's judgment, are life-threatening. As a Class Ia antiarrhythmic agent, disopyramide functions by blocking sodium channels in the cardiac cell membranes, which stabilizes cardiac electrical activity and can help restore a normal heart rhythm.

Synonyms and trade names

disopyramide; 3737-09-5; Dicorantil; Lispine; Disopiramida; Isorythm; Rythmodan P; Disopyramidum; Ritmilen; Dl-disopyramide; Searle-703; SC-7031; (rs)-disopyramide; DTXSID1045536; gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide; GFO928U8MQ

GHS hazard classification

Reported hazard statements	H302 (100%), H361 (90.5%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H361 (90.5%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

What the public record says

disopyramide free base · CAS 3737-09-5 · C21H29N3O. UNII GFO928U8MQ. Melting Point: 94.5-95 °C; Melting Point: 94.5 - 95 °C; Solubility: 44.9.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.