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disodium dihydrogen (dichloromethylene)diphosphonate

CAS 22560-50-5CH2Cl2Na2O6P2MW 288.85

disodium dihydrogen (dichloromethylene)diphosphonate (CAS 22560-50-5) — formula CH2Cl2Na2O6P2, molecular weight 288.85; category inorganic chemicals.

Product Overview

CAS Number22560-50-5
Molecular FormulaCH2Cl2Na2O6P2
Molecular Weight288.85
ApplicationsUses: A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification. For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors.
CategoryInorganic Chemicals

Applications

Documented applications: Uses: A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification. For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors..

Technical Profile

What this product is

disodium dihydrogen (dichloromethylene)diphosphonate is an inorganic compound with CAS registry number 22560-50-5 and molecular formula CH2Cl2Na2O6P2 (molecular weight 288.85), belonging to the inorganic chemicals segment of chemical raw materials.

Identification

CAS number: 22560-50-5

Its molecular formula CH2Cl2Na2O6P2 comprises 1 C, 2 H, 2 Cl, 2 Na, 6 O, 2 P atoms.

Also known as: disodium dihydrogen (dichloromethylene)diphosphonate · (二氯亚甲基)二磷酸二氢二钠

Category: inorganic chemicals

Frequently Asked Questions

What is the CAS number of disodium dihydrogen (dichloromethylene)diphosphonate?

The CAS registry number of disodium dihydrogen (dichloromethylene)diphosphonate is 22560-50-5.

What is the molecular formula and molecular weight of disodium dihydrogen (dichloromethylene)diphosphonate?

Molecular formula CH2Cl2Na2O6P2, molecular weight 288.85.

What other names is disodium dihydrogen (dichloromethylene)diphosphonate known by?

It is also registered under: disodium dihydrogen (dichloromethylene)diphosphonate, (二氯亚甲基)二磷酸二氢二钠.

What are the documented applications of disodium dihydrogen (dichloromethylene)diphosphonate?

Recorded applications: Uses: A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification. For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors..

Which category does disodium dihydrogen (dichloromethylene)diphosphonate belong to?

Category: Inorganic Chemicals.

PubChem Public Data

Independent reference data for disodium dihydrogen (dichloromethylene)diphosphonate (CAS 22560-50-5), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number22560-50-5
PubChem CID31195
Molecular formulaCH2Cl2Na2O6P2
IUPAC namedisodium;[dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate
UNII (FDA)Y05R4GCQ1H

Computed descriptors

Molecular Weight288.85
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass287.8499057
Monoisotopic Mass287.8499057
Topological Polar Surface Area121
Heavy Atom Count13

Documented uses on record

  • A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification. For the management of hypercalcemia of malignancy and as an adjunct in the management of osteolysis resulting from bone metastases of malignant tumors.
  • Clodronate is not metabolized in humans. It can be metabolized intracellularly to a beta-gamma-methylene (AppCp-type) analog of ATP (AppCCl2p), which is cytotoxic to macrophages in vitro. Half Life: Approximately 13 hours.

Synonyms and trade names

Clodronic acid disodium salt; 22560-50-5; Disodium clodronate; Ostac; Clodronate sodium; Sodium clodronate; Mebonat; Ossiten; Clodronate disodium anhydrous; Disodium dichloromethylene diphosphonate; DTXSID3045225; Disodium (dichloromethylene)diphosphonate; Disodium (dichloromethylene)bisphosphonate; Y05R4GCQ1H; Phosphonic acid, (dichloromethylene)bis-, disodium salt; DTXCID1025225

GHS hazard classification

Reported hazard statementsH373 (96.3%), H411 (100%)

H373 (96.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

H411 (100%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

What the public record says

disodium dihydrogen (dichloromethylene)diphosphonate · CAS 22560-50-5 · CH2Cl2Na2O6P2. UNII Y05R4GCQ1H.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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