Dimethyloldimethyl hydantoin（CAS 6440-58-0）：分子式 C7H12N2O4、分子量 188.18；类别 有机化学品。
| CAS号 | 6440-58-0 |
|---|---|
| 分子式 | C7H12N2O4 |
| 分子量 | 188.18 |
| 熔点 | 90 °C /OECD Guideline 102/ |
| LogP | log Kow = -2.9 |
| 应用领域 | Uses: CIR ingredient: DMDM Hydantoin、Used as a biocide in cosmetics with 0.6% the maximum allowable concentration in the EU、[Kanerva、p. 398、407] Used as an antimicrobial pesticide in cleaning products、adhesives、air fresheners、caulks、hydraulic fluids、inks、metal working cutting fluids、paints、stains、coatings、paper and paperboard coatings、polishes、synthetic polymers、sealants、starch solutions、resin emulsions、textiles、and wax、[Reference #1]、Metal Machining [Category: Heat or Machine]、Pulp and Paper Processing [Category: Industry]、Painting (Pigments、Binders、and Biocides) [Category: Paint]、Working with Glues and Adhesives [Category: Other]、Using Disinfectants or Biocides [Category: Clean]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、For 1、3-dimethylol-5、5-dimethylhydantoin (USEPA、OPP Pesticide Code: 115501) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、DMDM Hydantoin is a cosmetic preservative. It is described as being a broad-spectrum antimicrobial agent、effective against fungi、yeast、and gram-positive and gram-negative bacteria.、DMDM Hydantoin is a preservative which is used in cosmetic products at concentrations up to 1%. This ingredient is a formaldehyde donor containing up to 2% of the free aldehyde in equilibrium with the hydantoin.、Preserves and aids in the control of bacteria and fungi in liquid detergents、fabric softeners、household cleaning products、soft soaps、water-based paints for household and industrial use、room deodorizers and air fresheners、water-based surfactants、polymer emulsions、protective or decorative coatings、water-based gels for household and industrial products、water-based adhesives、sealants and caulks、latex for paper coatings、and water-based inks.、Dantogard XL-1000、For more Uses (Complete) data for 1、3-DIMETHYLOL-5、5-DIMETHYLHYDANTOIN (10 total)、please visit the HSDB record page.、1、3-Dimethylol-5、5-dimethylhydantoin (DMDM hydantoin) is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. It is used in the cosmetics industry and found in products like shampoos、hair conditioners and skin care products. (L1896)、Use Classification: Cosmetics -> Preservative、Industry Uses: Intermediate、Preservative、Consumer Uses: Preservative、Not Known or Reasonably Ascertainable、Household Products: Information on 803 consumer products that contain DMDM hydantoin in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Home Maintenance、• Inside the Home、• Personal Care、• Pet Care、Methods of Manufacturing: DMDM Hydantoin is produced by reacting 3 to 5 moles of formaldehyde、as the 37% by weight aqueous solution、with 1 mole of dimethylhydantoin at 84 °C. A highly concentrated aqueous solution of the compound is prepared by reacting 2 moles of formaldehyde、as 37% formalin、with dimethylhydantoin at 38 to 50 °C、pH 8.1 to 8.3.、Formulations、Preparations: It is available in solid and in aqueous solution forms、including low free formaldehyde versions of the latter.、Troysan 680 (Troy Chemical Corporation): Active ingredient: 1、2-benzisothiazolin-3-one 10.9%、2、4-Imidazolidinedione、3-bis(hydroxymethyl)-5、5-dimethyl- 12.5%、1-(hydroxymethyl)-5、5-dimethyl- 2.9%.、Glycoserve LAD (Lonza Inc.): Active ingredient: 2、4-imidazolidinedione、5-dimethyl- 45.0%、5-dimethyl- 10.0%.、Glycoserve (Lonza Inc.): Active ingredient: 2、For more Formulations、Preparations (Complete) data for 1、5-DIMETHYLHYDANTOIN (17 total)、U.S. Production: 2023: 1、275、131 lb、2022: 3、043、011 lb、2021: 4、514、565 lb、2020: 5、849、169 lb、This chemical is listed as an Extended High Production Volume (EHPV). Chemicals listed as EHPV were produced in or imported into the U.S. in >1 million pounds according to the 2002 Toxic Substances Control Act (TSCA) Inventory Update. The EHPV program is a voluntary initiative that allows companies to demonstrate that adequate screening data exist for organic HPV chemicals.、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7145]、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: 2、5-dimethyl-. Aggregated National Production Volume: 1 to < 10 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: 2、5-dimethyl-. National Production Volume: Withheld.、General Manufacturing Information: All Other Chemical Product and Preparation Manufacturing、Other (requires additional information)、5-dimethyl-: ACTIVE、The composition of DMDM Hydantoin as determined by gas chromatography is as follows: 94-98% DMDM hydantoin、2.5-3.0% monomethyloldimethylhydantoin、and other dimethylhydantoin formaldehyde products comprise the balance.、Supplied as a 55.0% solution、Dantogard XL-1000 should be added to the formulation to be preserved at a rate of 1.0 to 10.0 lbs per 1、000 lbs or 0.1% to 1.0% or 1、000 to 10、000 pp based upon the total weight of the product to be protected. If ... articles have been treated with Dantogard XL-1000、do not use them as components in materials used in food packaging and food-holding.、DMDM hydantoin |
| 类别 | Organic Chemicals |
登记用途：Uses: CIR ingredient: DMDM Hydantoin、Used as a biocide in cosmetics with 0.6% the maximum allowable concentration in the EU、[Kanerva、p. 398、407] Used as an antimicrobial pesticide in cleaning products、adhesives、air fresheners、caulks、hydraulic fluids、inks、metal working cutting fluids、paints、stains、coatings、paper and paperboard coatings、polishes、synthetic polymers、sealants、starch solutions、resin emulsions、textiles、and wax、[Reference #1]、Metal Machining [Category: Heat or Machine]、Pulp and Paper Processing [Category: Industry]、Painting (Pigments、Binders、and Biocides) [Category: Paint]、Working with Glues and Adhesives [Category: Other]、Using Disinfectants or Biocides [Category: Clean]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、For 1、3-dimethylol-5、5-dimethylhydantoin (USEPA、OPP Pesticide Code: 115501) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、DMDM Hydantoin is a cosmetic preservative. It is described as being a broad-spectrum antimicrobial agent、effective against fungi、yeast、and gram-positive and gram-negative bacteria.、DMDM Hydantoin is a preservative which is used in cosmetic products at concentrations up to 1%. This ingredient is a formaldehyde donor containing up to 2% of the free aldehyde in equilibrium with the hydantoin.、Preserves and aids in the control of bacteria and fungi in liquid detergents、fabric softeners、household cleaning products、soft soaps、water-based paints for household and industrial use、room deodorizers and air fresheners、water-based surfactants、polymer emulsions、protective or decorative coatings、water-based gels for household and industrial products、water-based adhesives、sealants and caulks、latex for paper coatings、and water-based inks.、Dantogard XL-1000、For more Uses (Complete) data for 1、3-DIMETHYLOL-5、5-DIMETHYLHYDANTOIN (10 total)、please visit the HSDB record page.、1、3-Dimethylol-5、5-dimethylhydantoin (DMDM hydantoin) is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. It is used in the cosmetics industry and found in products like shampoos、hair conditioners and skin care products. (L1896)、Use Classification: Cosmetics -> Preservative、Industry Uses: Intermediate、Preservative、Consumer Uses: Preservative、Not Known or Reasonably Ascertainable、Household Products: Information on 803 consumer products that contain DMDM hydantoin in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Home Maintenance、• Inside the Home、• Personal Care、• Pet Care、Methods of Manufacturing: DMDM Hydantoin is produced by reacting 3 to 5 moles of formaldehyde、as the 37% by weight aqueous solution、with 1 mole of dimethylhydantoin at 84 °C. A highly concentrated aqueous solution of the compound is prepared by reacting 2 moles of formaldehyde、as 37% formalin、with dimethylhydantoin at 38 to 50 °C、pH 8.1 to 8.3.、Formulations、Preparations: It is available in solid and in aqueous solution forms、including low free formaldehyde versions of the latter.、Troysan 680 (Troy Chemical Corporation): Active ingredient: 1、2-benzisothiazolin-3-one 10.9%、2、4-Imidazolidinedione、3-bis(hydroxymethyl)-5、5-dimethyl- 12.5%、1-(hydroxymethyl)-5、5-dimethyl- 2.9%.、Glycoserve LAD (Lonza Inc.): Active ingredient: 2、4-imidazolidinedione、5-dimethyl- 45.0%、5-dimethyl- 10.0%.、Glycoserve (Lonza Inc.): Active ingredient: 2、For more Formulations、Preparations (Complete) data for 1、5-DIMETHYLHYDANTOIN (17 total)、U.S. Production: 2023: 1、275、131 lb、2022: 3、043、011 lb、2021: 4、514、565 lb、2020: 5、849、169 lb、This chemical is listed as an Extended High Production Volume (EHPV). Chemicals listed as EHPV were produced in or imported into the U.S. in >1 million pounds according to the 2002 Toxic Substances Control Act (TSCA) Inventory Update. The EHPV program is a voluntary initiative that allows companies to demonstrate that adequate screening data exist for organic HPV chemicals.、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7145]、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: 2、5-dimethyl-. Aggregated National Production Volume: 1 to < 10 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: 2、5-dimethyl-. National Production Volume: Withheld.、General Manufacturing Information: All Other Chemical Product and Preparation Manufacturing、Other (requires additional information)、5-dimethyl-: ACTIVE、The composition of DMDM Hydantoin as determined by gas chromatography is as follows: 94-98% DMDM hydantoin、2.5-3.0% monomethyloldimethylhydantoin、and other dimethylhydantoin formaldehyde products comprise the balance.、Supplied as a 55.0% solution、Dantogard XL-1000 should be added to the formulation to be preserved at a rate of 1.0 to 10.0 lbs per 1、000 lbs or 0.1% to 1.0% or 1、000 to 10、000 pp based upon the total weight of the product to be protected. If ... articles have been treated with Dantogard XL-1000、do not use them as components in materials used in food packaging and food-holding.、DMDM hydantoin。
Dimethyloldimethyl hydantoin 是一种以碳骨架为基础的有机化合物，登记 CAS 号为 6440-58-0，分子式 C7H12N2O4（分子量 188.18），归属于有机化学品大类化工原料。
登记 CAS 号：6440-58-0
其分子式 C7H12N2O4 由 7 个碳、12 个氢、2 个氮、4 个氧 组成。
别名/同义词：Dimethyloldimethyl hydantoin · 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
所属分类：有机化学品
Dimethyloldimethyl hydantoin 的 CAS 登记号为 6440-58-0。
分子式 C7H12N2O4，分子量 188.18。
别名/同义词：Dimethyloldimethyl hydantoin、1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione。
登记用途：Uses: CIR ingredient: DMDM Hydantoin、Used as a biocide in cosmetics with 0.6% the maximum allowable concentration in the EU、[Kanerva、p. 398、407] Used as an antimicrobial pesticide in cleaning products、adhesives、air fresheners、caulks、hydraulic fluids、inks、metal working cutting fluids、paints、stains、coatings、paper and paperboard coatings、polishes、synthetic polymers、sealants、starch solutions、resin emulsions、textiles、and wax、[Reference #1]、Metal Machining [Category: Heat or Machine]、Pulp and Paper Processing [Category: Industry]、Painting (Pigments、Binders、and Biocides) [Category: Paint]、Working with Glues and Adhesives [Category: Other]、Using Disinfectants or Biocides [Category: Clean]、Textiles (Printing、Dyeing、or Finishing) [Category: Industry]、For 1、3-dimethylol-5、5-dimethylhydantoin (USEPA、OPP Pesticide Code: 115501) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、DMDM Hydantoin is a cosmetic preservative. It is described as being a broad-spectrum antimicrobial agent、effective against fungi、yeast、and gram-positive and gram-negative bacteria.、DMDM Hydantoin is a preservative which is used in cosmetic products at concentrations up to 1%. This ingredient is a formaldehyde donor containing up to 2% of the free aldehyde in equilibrium with the hydantoin.、Preserves and aids in the control of bacteria and fungi in liquid detergents、fabric softeners、household cleaning products、soft soaps、water-based paints for household and industrial use、room deodorizers and air fresheners、water-based surfactants、polymer emulsions、protective or decorative coatings、water-based gels for household and industrial products、water-based adhesives、sealants and caulks、latex for paper coatings、and water-based inks.、Dantogard XL-1000、For more Uses (Complete) data for 1、3-DIMETHYLOL-5、5-DIMETHYLHYDANTOIN (10 total)、please visit the HSDB record page.、1、3-Dimethylol-5、5-dimethylhydantoin (DMDM hydantoin) is an antimicrobial formaldehyde releaser preservative with the trade name Glydant. It is used in the cosmetics industry and found in products like shampoos、hair conditioners and skin care products. (L1896)、Use Classification: Cosmetics -> Preservative、Industry Uses: Intermediate、Preservative、Consumer Uses: Preservative、Not Known or Reasonably Ascertainable、Household Products: Information on 803 consumer products that contain DMDM hydantoin in the following categories is provided:、• Auto Products、• Commercial、Institutional、• Home Maintenance、• Inside the Home、• Personal Care、• Pet Care、Methods of Manufacturing: DMDM Hydantoin is produced by reacting 3 to 5 moles of formaldehyde、as the 37% by weight aqueous solution、with 1 mole of dimethylhydantoin at 84 °C. A highly concentrated aqueous solution of the compound is prepared by reacting 2 moles of formaldehyde、as 37% formalin、with dimethylhydantoin at 38 to 50 °C、pH 8.1 to 8.3.、Formulations、Preparations: It is available in solid and in aqueous solution forms、including low free formaldehyde versions of the latter.、Troysan 680 (Troy Chemical Corporation): Active ingredient: 1、2-benzisothiazolin-3-one 10.9%、2、4-Imidazolidinedione、3-bis(hydroxymethyl)-5、5-dimethyl- 12.5%、1-(hydroxymethyl)-5、5-dimethyl- 2.9%.、Glycoserve LAD (Lonza Inc.): Active ingredient: 2、4-imidazolidinedione、5-dimethyl- 45.0%、5-dimethyl- 10.0%.、Glycoserve (Lonza Inc.): Active ingredient: 2、For more Formulations、Preparations (Complete) data for 1、5-DIMETHYLHYDANTOIN (17 total)、U.S. Production: 2023: 1、275、131 lb、2022: 3、043、011 lb、2021: 4、514、565 lb、2020: 5、849、169 lb、This chemical is listed as an Extended High Production Volume (EHPV). Chemicals listed as EHPV were produced in or imported into the U.S. in >1 million pounds according to the 2002 Toxic Substances Control Act (TSCA) Inventory Update. The EHPV program is a voluntary initiative that allows companies to demonstrate that adequate screening data exist for organic HPV chemicals.、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7145]、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: 2、5-dimethyl-. Aggregated National Production Volume: 1 to < 10 million pounds.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: 2、5-dimethyl-. National Production Volume: Withheld.、General Manufacturing Information: All Other Chemical Product and Preparation Manufacturing、Other (requires additional information)、5-dimethyl-: ACTIVE、The composition of DMDM Hydantoin as determined by gas chromatography is as follows: 94-98% DMDM hydantoin、2.5-3.0% monomethyloldimethylhydantoin、and other dimethylhydantoin formaldehyde products comprise the balance.、Supplied as a 55.0% solution、Dantogard XL-1000 should be added to the formulation to be preserved at a rate of 1.0 to 10.0 lbs per 1、000 lbs or 0.1% to 1.0% or 1、000 to 10、000 pp based upon the total weight of the product to be protected. If ... articles have been treated with Dantogard XL-1000、do not use them as components in materials used in food packaging and food-holding.、DMDM hydantoin。
所属分类：Organic Chemicals。
Dimethyloldimethyl hydantoin（CAS 6440-58-0）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 6440-58-0 |
|---|---|
| PubChem CID | 22947 |
| 分子式 | C7H12N2O4 |
| IUPAC 名称 | 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione |
| UNII（FDA） | BYR0546TOW |
| Molecular Weight | 188.18 |
|---|---|
| XLogP3 | -0.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 188.07970687 |
| Monoisotopic Mass | 188.07970687 |
| Topological Polar Surface Area | 81.1 |
| Heavy Atom Count | 13 |
| Melting Point | 90 °C /OECD Guideline 102/ |
|---|---|
| Melting Point | MP: 102-104 °C /Technical/ |
| Vapor Pressure | 0.00000009 [mmHg] |
| Vapor Pressure | 9.0X10-8 mm Hg at 25 °C |
| LogP | log Kow = -2.9 |
| Surface Tension | 72.4 mN/m at 20 °C /0.998 g/L solution/ |
6440-58-0; DMDM Hydantoin; Dmdmh; Glydant; 1,3-Bis(hydroxymethyl)-5,5-dimethylhydantoin; 1,3-Dimethylol-5,5-dimethylhydantoin; Dantoin-DMDMH; Glycoserve-DMDMH; Dantoin dmdmh 55; Dimethylol-5,5-dimethylhydantoin; Dmdmh 55; 2,4-Imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-; DTXSID8035217; 1,3-Bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione; BYR0546TOW; DTXCID6015217
| 法规与食品接触 | FDA 21 CFR 中列出的食品接触物质清单：FCS CIR / INCI: Cosmetic ingredients (DMDM Hydantoin) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Preservative |
|---|---|
| GHS 通报统计 | 11.3% (83 / 737) |
| GHS 通报统计 | 11.3% (83 / 737) |
|---|---|
| 已通报的危害声明 | H302 (67.4%), H315 (11.1%), H317 (14.7%), H319 (30%), H334 (13.8%) |
1,3-二羟甲基-5,5-二甲基海因 · CAS 6440-58-0 · C7H12N2O4. UNII BYR0546TOW. Melting Point: 90 °C /OECD Guideline 102/; Melting Point: MP: 102-104 °C /Technical/; Vapor Pressure: 0.00000009 [mmHg].
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Dimethyloldimethyl hydantoin