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二甲基亚砜

CAS 67-68-5C2H6OSMW 78.14主营产品

二甲基亚砜(CAS 67-68-5):分子式 C2H6OS、分子量 78.14。

产品概览

CAS号67-68-5
分子式C2H6OS
分子量78.14
熔点65.3 °F (NTP, 1992)
沸点372 °F at 760 mmHg (NTP, 1992)
LogP-0.6
应用领域Uses: Used as a pharmaceutical、a solvent for polymerization and chemical extractions、a paint remover、a preservative for organ transplantation、Occurs naturally in ground water and in grains、vegetables、and many other foods、[CHEMINFO] Used as a solvent for many organic compounds、Also used in industrial cleaners、[HSDB]、Semiconductor Manufacturing [Category: Industry]、DMSO is not a nutritional supplement. It is used as a treatment for interstitial cystitis、and treatment must be performed by a qualified physician. DMSO is metabolized to methylsulfonylmethane、which is available as a nutritional supplement.、Vitrification has become common for cryopreservation of embryos. ...Extended exposure of embryos with both vitrification protocols showed that the DMSO-containing vitrification solutions did not lead to cell membrane damage and death as quickly as the DMSO-free vitrification solutions. To assess embryo viability、the authors recommend that vitrification of early embryos should be combined with extended culture and assessment of normal blastocyst development before transferring to patients.、Dimethyl sulfoxide (DMSO) is a molecule with a long history in pharmaceutics and is now well established as a penetration enhancer in topical pharmaceutical formulations. It is currently used for this purpose in diclofenac sodium topical solution (approved in the United States to treat signs and symptoms of osteoarthritis) and idoxuridine topical solution (approved in Europe for the treatment of herpes zoster). ... The clinical use of pharmaceutical-grade DMSO as a penetration enhancer is supported by the robust data that have accumulated over the past 3 decades demonstrating the favorable safety and tolerability profile. Dimethyl sulfoxide is a safe and effective mechanism for facilitating the transdermal delivery of both hydrophilic and lipophilic medications to provide localized drug delivery.、For dimethyl sulfoxide (USEPA、OPP Pesticide Code: 000177) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、For more Uses (Complete) data for DIMETHYL SULFOXIDE (13 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita、approx.) in Germany (2009): 0.122、Excretion rate: 0.68、Calculated removal (%): 75.1、DMSO is an important polar aprotic solvent. In cryobiology DMSO has been used as a cryoprotectant and is still an important constituent of cryoprotectant vitrification mixtures used to preserve organs、tissues、and cell suspensions.[Wikipedia]、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、SOLVENTS、Industry Uses: Laboratory chemicals、Etching agent、Not Known or Reasonably Ascertainable、Cleaning agent、Plating agent、Solvent、Consumer Uses: Solvent、Soil amendments (fertilizers)、Household Products: Information on 1 consumer products that contain Dimethyl sulfoxide in the following categories is provided:、• Home Maintenance、Methods of Manufacturing: In industry、DMSO is produced by catalytic oxidation of dimethyl sulfide with oxygen or by oxidation with nitrogen dioxide. The oxidation of dimethyl sulfide with oxygen at 7.2 MPa and 105 °C gives good yields of DMSO.、Obtained as a by-product of paper manufacture ... .、Oxidation of dimethyl sulfide with nitrogen tetroxide under anhydrous conditions、sulfide waste liquors.、Formulations、Preparations: Rimso-50 (Research Industries) Solution: 50% aqueous solution.、Dimethyl Sulfoxide (Bioniche)、Solution: 50% aqueous solution、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 2、2021: 2、2020: 2、(1972) Probably greater than 4.54x10+5 g、(1975) probably greater than 4.54x10+5 g、Methane、sulfinylbis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#221]、For more U.S. Production (Complete) data for DIMETHYL SULFOXIDE (6 total)、Computer and Electronic Product Manufacturing、Plastics Product Manufacturing、Transportation Equipment Manufacturing、Electrical Equipment、Appliance、and Component Manufacturing、Pharmaceutical and Medicine Manufacturing、All Other Basic Organic Chemical Manufacturing、Services、Machinery Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Fabricated Metal Product Manufacturing、1、1'-sulfinylbis-: ACTIVE、FDA does not permit its use in horses or dogs intended for breeding purposes、nor in horses slaughtered for food.、Dimethyl sulfoxide is used in many paint removers and has many green characteristics. It has low toxicity、a high flash point、and is not a HAP nor listed under SARA 313. A risk associated with DMSO removers is that it is readily transported through the skin and may readily carry toxic compounds present with it.

应用领域

登记用途:Uses: Used as a pharmaceutical、a solvent for polymerization and chemical extractions、a paint remover、a preservative for organ transplantation、Occurs naturally in ground water and in grains、vegetables、and many other foods、[CHEMINFO] Used as a solvent for many organic compounds、Also used in industrial cleaners、[HSDB]、Semiconductor Manufacturing [Category: Industry]、DMSO is not a nutritional supplement. It is used as a treatment for interstitial cystitis、and treatment must be performed by a qualified physician. DMSO is metabolized to methylsulfonylmethane、which is available as a nutritional supplement.、Vitrification has become common for cryopreservation of embryos. ...Extended exposure of embryos with both vitrification protocols showed that the DMSO-containing vitrification solutions did not lead to cell membrane damage and death as quickly as the DMSO-free vitrification solutions. To assess embryo viability、the authors recommend that vitrification of early embryos should be combined with extended culture and assessment of normal blastocyst development before transferring to patients.、Dimethyl sulfoxide (DMSO) is a molecule with a long history in pharmaceutics and is now well established as a penetration enhancer in topical pharmaceutical formulations. It is currently used for this purpose in diclofenac sodium topical solution (approved in the United States to treat signs and symptoms of osteoarthritis) and idoxuridine topical solution (approved in Europe for the treatment of herpes zoster). ... The clinical use of pharmaceutical-grade DMSO as a penetration enhancer is supported by the robust data that have accumulated over the past 3 decades demonstrating the favorable safety and tolerability profile. Dimethyl sulfoxide is a safe and effective mechanism for facilitating the transdermal delivery of both hydrophilic and lipophilic medications to provide localized drug delivery.、For dimethyl sulfoxide (USEPA、OPP Pesticide Code: 000177) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、For more Uses (Complete) data for DIMETHYL SULFOXIDE (13 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita、approx.) in Germany (2009): 0.122、Excretion rate: 0.68、Calculated removal (%): 75.1、DMSO is an important polar aprotic solvent. In cryobiology DMSO has been used as a cryoprotectant and is still an important constituent of cryoprotectant vitrification mixtures used to preserve organs、tissues、and cell suspensions.[Wikipedia]、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、SOLVENTS、Industry Uses: Laboratory chemicals、Etching agent、Not Known or Reasonably Ascertainable、Cleaning agent、Plating agent、Solvent、Consumer Uses: Solvent、Soil amendments (fertilizers)、Household Products: Information on 1 consumer products that contain Dimethyl sulfoxide in the following categories is provided:、• Home Maintenance、Methods of Manufacturing: In industry、DMSO is produced by catalytic oxidation of dimethyl sulfide with oxygen or by oxidation with nitrogen dioxide. The oxidation of dimethyl sulfide with oxygen at 7.2 MPa and 105 °C gives good yields of DMSO.、Obtained as a by-product of paper manufacture ... .、Oxidation of dimethyl sulfide with nitrogen tetroxide under anhydrous conditions、sulfide waste liquors.、Formulations、Preparations: Rimso-50 (Research Industries) Solution: 50% aqueous solution.、Dimethyl Sulfoxide (Bioniche)、Solution: 50% aqueous solution、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 2、2021: 2、2020: 2、(1972) Probably greater than 4.54x10+5 g、(1975) probably greater than 4.54x10+5 g、Methane、sulfinylbis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#221]、For more U.S. Production (Complete) data for DIMETHYL SULFOXIDE (6 total)、Computer and Electronic Product Manufacturing、Plastics Product Manufacturing、Transportation Equipment Manufacturing、Electrical Equipment、Appliance、and Component Manufacturing、Pharmaceutical and Medicine Manufacturing、All Other Basic Organic Chemical Manufacturing、Services、Machinery Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Fabricated Metal Product Manufacturing、1、1'-sulfinylbis-: ACTIVE、FDA does not permit its use in horses or dogs intended for breeding purposes、nor in horses slaughtered for food.、Dimethyl sulfoxide is used in many paint removers and has many green characteristics. It has low toxicity、a high flash point、and is not a HAP nor listed under SARA 313. A risk associated with DMSO removers is that it is readily transported through the skin and may readily carry toxic compounds present with it.。

技术档案

这个产品是什么

二甲基亚砜 是一种化工化合物,登记 CAS 号为 67-68-5,分子式 C2H6OS(分子量 78.14)。

识别信息

登记 CAS 号:67-68-5

其分子式 C2H6OS 由 2 个碳、6 个氢、1 个氧、1 个硫 组成。

别名/同义词:二甲基亚砜 · Dimethyl sulfoxide · methylsulfinylmethane

常见问题

二甲基亚砜 的 CAS 号是多少?

二甲基亚砜 的 CAS 登记号为 67-68-5。

二甲基亚砜 的分子式与分子量是多少?

分子式 C2H6OS,分子量 78.14。

二甲基亚砜 还有哪些别名?

别名/同义词:二甲基亚砜、Dimethyl sulfoxide、methylsulfinylmethane。

二甲基亚砜 的登记用途是什么?

登记用途:Uses: Used as a pharmaceutical、a solvent for polymerization and chemical extractions、a paint remover、a preservative for organ transplantation、Occurs naturally in ground water and in grains、vegetables、and many other foods、[CHEMINFO] Used as a solvent for many organic compounds、Also used in industrial cleaners、[HSDB]、Semiconductor Manufacturing [Category: Industry]、DMSO is not a nutritional supplement. It is used as a treatment for interstitial cystitis、and treatment must be performed by a qualified physician. DMSO is metabolized to methylsulfonylmethane、which is available as a nutritional supplement.、Vitrification has become common for cryopreservation of embryos. ...Extended exposure of embryos with both vitrification protocols showed that the DMSO-containing vitrification solutions did not lead to cell membrane damage and death as quickly as the DMSO-free vitrification solutions. To assess embryo viability、the authors recommend that vitrification of early embryos should be combined with extended culture and assessment of normal blastocyst development before transferring to patients.、Dimethyl sulfoxide (DMSO) is a molecule with a long history in pharmaceutics and is now well established as a penetration enhancer in topical pharmaceutical formulations. It is currently used for this purpose in diclofenac sodium topical solution (approved in the United States to treat signs and symptoms of osteoarthritis) and idoxuridine topical solution (approved in Europe for the treatment of herpes zoster). ... The clinical use of pharmaceutical-grade DMSO as a penetration enhancer is supported by the robust data that have accumulated over the past 3 decades demonstrating the favorable safety and tolerability profile. Dimethyl sulfoxide is a safe and effective mechanism for facilitating the transdermal delivery of both hydrophilic and lipophilic medications to provide localized drug delivery.、For dimethyl sulfoxide (USEPA、OPP Pesticide Code: 000177) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、For more Uses (Complete) data for DIMETHYL SULFOXIDE (13 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita、approx.) in Germany (2009): 0.122、Excretion rate: 0.68、Calculated removal (%): 75.1、DMSO is an important polar aprotic solvent. In cryobiology DMSO has been used as a cryoprotectant and is still an important constituent of cryoprotectant vitrification mixtures used to preserve organs、tissues、and cell suspensions.[Wikipedia]、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、SOLVENTS、Industry Uses: Laboratory chemicals、Etching agent、Not Known or Reasonably Ascertainable、Cleaning agent、Plating agent、Solvent、Consumer Uses: Solvent、Soil amendments (fertilizers)、Household Products: Information on 1 consumer products that contain Dimethyl sulfoxide in the following categories is provided:、• Home Maintenance、Methods of Manufacturing: In industry、DMSO is produced by catalytic oxidation of dimethyl sulfide with oxygen or by oxidation with nitrogen dioxide. The oxidation of dimethyl sulfide with oxygen at 7.2 MPa and 105 °C gives good yields of DMSO.、Obtained as a by-product of paper manufacture ... .、Oxidation of dimethyl sulfide with nitrogen tetroxide under anhydrous conditions、sulfide waste liquors.、Formulations、Preparations: Rimso-50 (Research Industries) Solution: 50% aqueous solution.、Dimethyl Sulfoxide (Bioniche)、Solution: 50% aqueous solution、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 2、2021: 2、2020: 2、(1972) Probably greater than 4.54x10+5 g、(1975) probably greater than 4.54x10+5 g、Methane、sulfinylbis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#221]、For more U.S. Production (Complete) data for DIMETHYL SULFOXIDE (6 total)、Computer and Electronic Product Manufacturing、Plastics Product Manufacturing、Transportation Equipment Manufacturing、Electrical Equipment、Appliance、and Component Manufacturing、Pharmaceutical and Medicine Manufacturing、All Other Basic Organic Chemical Manufacturing、Services、Machinery Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Fabricated Metal Product Manufacturing、1、1'-sulfinylbis-: ACTIVE、FDA does not permit its use in horses or dogs intended for breeding purposes、nor in horses slaughtered for food.、Dimethyl sulfoxide is used in many paint removers and has many green characteristics. It has low toxicity、a high flash point、and is not a HAP nor listed under SARA 313. A risk associated with DMSO removers is that it is readily transported through the skin and may readily carry toxic compounds present with it.。

PubChem 公开数据

二甲基亚砜(CAS 67-68-5)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number67-68-5
PubChem CID679
Molecular formulaC2H6OS
Molecular weight78.01 g/mol
IUPAC namemethylsulfinylmethane
InChIKeyIAZDPXIOMUYVGZ-UHFFFAOYSA-N
UNII (FDA)YOW8V9698H
ChEBI IDCHEBI:28262
ATC code (WHO)G04BX13
FEMA number3875
JECFA number507

计算分子描述符

Molecular Weight78.14
XLogP3-0.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass78.01393598
Monoisotopic Mass78.01393598
Topological Polar Surface Area36.3
Heavy Atom Count4

在册的理化数值

Boiling Point372 °F at 760 mmHg (NTP, 1992)
Boiling Point63
Boiling Point189 °C
Boiling Point189.00 to 190.00 °C. @ 760.00 mm Hg
Boiling Point189 °C @760 [mm Hg]
Melting Point65.3 °F (NTP, 1992)
Melting Point18.5
Melting Point18.45 °C
Melting Point18.5 °C
Melting Point17.89 °C

在册的记载用途

    Used as a pharmaceutical, a solvent for polymerization and chemical extractions, a paint remover, a preservative for organ transplantation; Occurs naturally in ground water and in grains, vegetables, and many other foods; [CHEMINFO] Used as a solvent for many organic compounds; Also used in industrial cleaners; [HSDB]Semiconductor Manufacturing [Category: Industry]

    同义词与商品名

    dimethyl sulfoxide; 67-68-5; DMSO; Methylsulfinylmethane; Methyl sulfoxide; Dimethyl sulphoxide; Dimethylsulfoxide; sulfinylbismethane; Demasorb; Domoso; Methane, sulfinylbis-; Demsodrox; Dromisol; Deltan; Demavet; Demeso

    已收录的法规名录

    Regulatory & Food ContactEU Flavoring substances
    FDA Substance added to food: FLAVORING AGENT OR ADJUVANT
    FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
    Flavoring Agents
    FLAVOURING_AGENT: Flavouring Agent
    Garlic
    GHS notification summary65.1% (611 / 938)

    GHS 危害分类

    GHS notification summary65.1% (611 / 938)
    Reported hazard statementsH315 (28.4%), H319 (33.6%), H335 (13.8%), H227, H371

    This chemical does not meet GHS hazard criteria for 65.1% (611 of 938) of all reports.

    H315 (28.4%): Causes skin irritation [Warning Skin corrosion/irritation]

    公开数据库对它的描述

    methylsulfinylmethane is identified by CAS 67-68-5, molecular formula C2H6OS and molecular weight 78.01 g/mol. UNII YOW8V9698H; ChEBI 28262; InChIKey IAZDPXIOMUYVGZ-UHFFFAOYSA-N. Boiling Point: 372 °F at 760 mmHg (NTP, 1992); Boiling Point: 63; Boiling Point: 189 °C.

    物理形态与操作说明

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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