Dilmapimod

Name: Dilmapimod
Brand: Jinan Shenghe Chemical Co., Ltd.
SKU: 9862

CAS 444606-18-2C23H19F3N4O3MW 456.4

Dilmapimod (CAS 444606-18-2) — formula C23H19F3N4O3, molecular weight 456.4.

Product Overview

CAS Number	444606-18-2
Molecular Formula	C23H19F3N4O3
Molecular Weight	456.4
LogP	3

Technical Profile

What this product is

Dilmapimod is a chemical compound with CAS registry number 444606-18-2 and molecular formula C23H19F3N4O3 (molecular weight 456.4).

Identification

CAS number: 444606-18-2

Its molecular formula C23H19F3N4O3 comprises 23 C, 19 H, 3 F, 4 N, 3 O atoms.

Also known as: Dilmapimod · 迪马匹莫德

Frequently Asked Questions

What is the CAS number of Dilmapimod?

The CAS registry number of Dilmapimod is 444606-18-2.

What is the molecular formula and molecular weight of Dilmapimod?

Molecular formula C23H19F3N4O3, molecular weight 456.4.

What other names is Dilmapimod known by?

It is also registered under: Dilmapimod, 迪马匹莫德.

PubChem Public Data

Independent reference data for Dilmapimod (CAS 444606-18-2), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	444606-18-2
PubChem CID	10297982
Molecular formula	C23H19F3N4O3
IUPAC name	8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7-one
UNII (FDA)	Q3238VQW0N

Computed descriptors

Molecular Weight	456.4
XLogP3	3
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	6
Exact Mass	456.14092497
Monoisotopic Mass	456.14092497
Topological Polar Surface Area	98.6
Heavy Atom Count	33

Documented uses on record

Dilmapimod has been used in trials studying the treatment and diagnostic of Nerve Trauma, Inflammation, Pain, Neuropathic, Arthritis, Rheumatoid, and Coronary Heart Disease, among others.
Dilmapimod reduces the levels of proinflammatory cytokines and chemokines and reduce cellular infiltration to sites of inflammation, thereby reducing local damage. In diseases such as RA and IBD, TNFα blockade through either anti-TNFα antibodies or use of soluble TNFα receptors. Inhibition of p38α offers significant inhibition of TNFα, and cytokines such as IL-1β and IL-6, which offer additional therapeutic efficacy.

Synonyms and trade names

Dilmapimod; 444606-18-2; SB-681323; Q3238VQW0N; SB681323; DTXSID101318338; dilmapimodum; GW681323; RefChem:587981; DTXCID401748150; Dilmapimod [USAN:INN]; GW 681323; UNII-Q3238VQW0N; SB 681323; GSK 681323; SB-681323; GW 681323

What the public record says

Dilmapimod · CAS 444606-18-2 · C23H19F3N4O3. UNII Q3238VQW0N.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

中文页面: 迪马匹莫德