二氢速甾醇结晶(CAS 67-96-9):分子式 C28H46O、分子量 398.7。
| CAS号 | 67-96-9 |
|---|---|
| 分子式 | C28H46O |
| 分子量 | 398.7 |
| 熔点 | 131 °C |
| LogP | 7.5 |
| 应用领域 | Uses: Treatment of hypocalcemic tetany、MEDICATION、MEDICATION (VET)、Bone Density Conservation Agents、Vitamins、Used for the prevention and treatment of rickets or osteomalacia、and to manage hypocalcemia associated with hypoparathyroidism or pseudohypoparathyroidism. Also used for the treatment of vitamin D dependent rickets、rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy、early renal osteodystrophy、osteoporosis (in conjunction with calcium)、and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis).、Methods of Manufacturing: ...Reduction of tachysterol、v. Werder、US PATENT 2228491 (1941 TO Winthrop)、Calciferol (activated ergosterol) is dissolved in suitable organic solvent & subjected to catalytic hydrogenation until proper amount of hydrogen has reacted.、Formulations、Preparations: Oral: Capsules 0.125 mg Hytakerol、(Sanofi-Aventis)、Solution、concentrate: 0.2 mg、mL DHT Intensol (with alcohol 20%)、(Roxane).、General Manufacturing Information: USP unit is identical with international unit & is equivalent to specific biological activity of 0.025 ug of vitamin D3 (ie 1 mg equals 40、000 units).、Vitamin D、Dihydrotachysterol (DHT) is analog of vitamin D that may be regarded as reduction product of either vitamin D2 (DHT2) or vitamin D3 (DHT3). DHT is about 1、450 as active as vitamin D in usual antirachitic assay、but at high doses it is much more effective than high doses of vitamin D in mobilizing calcium from bone.、Dihydrotachysterol or vitamin D2、both at 10-50 mg、L、increased production of adventitious roots in herbaceous cuttings of populus tremula (aspen) by approximately 60 and 100%、respectively. |
登记用途:Uses: Treatment of hypocalcemic tetany、MEDICATION、MEDICATION (VET)、Bone Density Conservation Agents、Vitamins、Used for the prevention and treatment of rickets or osteomalacia、and to manage hypocalcemia associated with hypoparathyroidism or pseudohypoparathyroidism. Also used for the treatment of vitamin D dependent rickets、rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy、early renal osteodystrophy、osteoporosis (in conjunction with calcium)、and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis).、Methods of Manufacturing: ...Reduction of tachysterol、v. Werder、US PATENT 2228491 (1941 TO Winthrop)、Calciferol (activated ergosterol) is dissolved in suitable organic solvent & subjected to catalytic hydrogenation until proper amount of hydrogen has reacted.、Formulations、Preparations: Oral: Capsules 0.125 mg Hytakerol、(Sanofi-Aventis)、Solution、concentrate: 0.2 mg、mL DHT Intensol (with alcohol 20%)、(Roxane).、General Manufacturing Information: USP unit is identical with international unit & is equivalent to specific biological activity of 0.025 ug of vitamin D3 (ie 1 mg equals 40、000 units).、Vitamin D、Dihydrotachysterol (DHT) is analog of vitamin D that may be regarded as reduction product of either vitamin D2 (DHT2) or vitamin D3 (DHT3). DHT is about 1、450 as active as vitamin D in usual antirachitic assay、but at high doses it is much more effective than high doses of vitamin D in mobilizing calcium from bone.、Dihydrotachysterol or vitamin D2、both at 10-50 mg、L、increased production of adventitious roots in herbaceous cuttings of populus tremula (aspen) by approximately 60 and 100%、respectively.。
二氢速甾醇结晶 是一种化工化合物,登记 CAS 号为 67-96-9,分子式 C28H46O(分子量 398.7)。
登记 CAS 号:67-96-9
其分子式 C28H46O 由 28 个碳、46 个氢、1 个氧 组成。
别名/同义词:二氢速甾醇结晶 · dihydrotachysterol crystalline
二氢速甾醇结晶 的 CAS 登记号为 67-96-9。
分子式 C28H46O,分子量 398.7。
别名/同义词:二氢速甾醇结晶、dihydrotachysterol crystalline。
登记用途:Uses: Treatment of hypocalcemic tetany、MEDICATION、MEDICATION (VET)、Bone Density Conservation Agents、Vitamins、Used for the prevention and treatment of rickets or osteomalacia、and to manage hypocalcemia associated with hypoparathyroidism or pseudohypoparathyroidism. Also used for the treatment of vitamin D dependent rickets、rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy、early renal osteodystrophy、osteoporosis (in conjunction with calcium)、and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis).、Methods of Manufacturing: ...Reduction of tachysterol、v. Werder、US PATENT 2228491 (1941 TO Winthrop)、Calciferol (activated ergosterol) is dissolved in suitable organic solvent & subjected to catalytic hydrogenation until proper amount of hydrogen has reacted.、Formulations、Preparations: Oral: Capsules 0.125 mg Hytakerol、(Sanofi-Aventis)、Solution、concentrate: 0.2 mg、mL DHT Intensol (with alcohol 20%)、(Roxane).、General Manufacturing Information: USP unit is identical with international unit & is equivalent to specific biological activity of 0.025 ug of vitamin D3 (ie 1 mg equals 40、000 units).、Vitamin D、Dihydrotachysterol (DHT) is analog of vitamin D that may be regarded as reduction product of either vitamin D2 (DHT2) or vitamin D3 (DHT3). DHT is about 1、450 as active as vitamin D in usual antirachitic assay、but at high doses it is much more effective than high doses of vitamin D in mobilizing calcium from bone.、Dihydrotachysterol or vitamin D2、both at 10-50 mg、L、increased production of adventitious roots in herbaceous cuttings of populus tremula (aspen) by approximately 60 and 100%、respectively.。
二氢速甾醇结晶(CAS 67-96-9)的独立参考数据,整理自公开化学数据库。
| CAS Registry Number | 67-96-9 |
|---|---|
| PubChem CID | 5311071 |
| Molecular formula | C28H46O |
| IUPAC name | trans-(1S,3E,4S)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylcyclohexan-1-ol |
| UNII (FDA) | R5LM3H112R |
| Molecular Weight | 398.7 |
|---|---|
| XLogP3 | 7.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 5 |
| Exact Mass | 398.354866087 |
| Monoisotopic Mass | 398.354866087 |
| Topological Polar Surface Area | 20.2 |
| Heavy Atom Count | 29 |
| Melting Point | 131 °C |
|---|---|
| Melting Point | 126 °C |
| Solubility | 1.25e-04 g/L |
| LogP | 7.5 |
dihydrotachysterol; Dichystrolum; 67-96-9; Antitanil; Hytakerol; Tachystin; Dihidrotaquisterol; Dihydrotachysterol2; Dihydral; Dygratyl; Parterol; Tachyrol; Anti-tetany substance 10; Dihydrotachysterolum; DHT2; Diidrotachisterolo
| Reported hazard statements | H301 (97.6%) |
|---|
H301 (97.6%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
dihydrotachysterol crystalline · CAS 67-96-9 · C28H46O. UNII R5LM3H112R. Melting Point: 131 °C; Melting Point: 126 °C; Solubility: 1.25e-04 g/L.
数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。
English page: dihydrotachysterol crystalline