3,4-二氢香豆素（CAS 119-84-6）：分子式 C9H8O2、分子量 148.16。
| CAS号 | 119-84-6 |
|---|---|
| 分子式 | C9H8O2 |
| 分子量 | 148.16 |
| 熔点 | 77 °F (NTP, 1992) |
| 沸点 | 522 °F at 760 mmHg (NTP, 1992) |
| LogP | 1.6 |
| 应用领域 | Uses: Used in perfumes and flavors--has GRAS status in US、[HSDB]、...Used in perfumery industry for its haylike odor.、It has GRAS status and can be used as a food flavor ingredient with a sweet caramel-like taste.、... In woodruff-type flavor compositions.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Methods of Manufacturing: Hydrogenation of coumarin ... with a Raney nickel catalyst under moderate conditions yields 3、4-dihydrocoumarin.、IFRA Fragrance Standards: Dihydrocoumarin、Dihydrocoumarin、1、2-Benzodihydropyrone、2H-1-Benzopyran-2-one、3、4-dihydro-、Chroman-2-one、2-Chromanone、4-Dihydro-2H-1-benzopyran-2-one、o-Hydroxydihydrocinnamic acid lactone、Melilotic acid lactone、Melilotic lactone (commercial name)、IFRA_STD_029.pdf、51、IFRA 51st Amendment - Guidance for the use of IFRA Standards、Restriction: This material should be used only in the limited quantity as stated in the Standard、DERMAL SENSITIZATION AND SYSTEMIC TOXICITY、Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6、materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.、Restriction Limits in the Finished Product (%): 0.038 [Products applied to the lips]、0.011 [Products applied to the axillae]、0.23 [Products applied to the face、body using fingertips]、0.21 [Products related to fine fragrances]、0.053 [Products applied to the body using the hands (palms)、primarily leave-on (Body lotion)]、0.053 [Products applied to the face using the hands (palms)、primarily leave-on (Face moisturizer)]、0.053 [Products applied to the hands using the hands (palms)、primarily leave-on (Hand cream)]、0.018 [Products applied to babies using the hands (palms)、primarily leave-on (Baby cream、oil、talc)]、0.12 [Products with oral and lip exposure]、0.43 [Rinse-off products applied to the hair with some hand contact]、0.43 [Leave-on products applied to the hair with some hand contact]、0.018 [Products with significant anogenital exposure (tampon)]、0.41 [Products with body and hand exposure、primarily rinse off]、1.5 [Household care products with mostly hand contact (excluding aerosol、spray products)]、1.5 [Household care products with mostly hand contact (household aerosol、0.018 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure]、0.018 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure]、No restriction [Other air care products not intended for direct skin contact、minimal or insignificant transfer to skin]、U.S. Production: (1974) 4.5X10+6 G-MAX CONSUMPTION AS FRAGRANCE、(1979) PROBABLY GREATER THAN 1.36X10+6 GRAMS、The U.S. market is estimated at 50 tons、yr.、U.S. Imports: (1977) 2.00X10+5 GRAMS (PRINCPL CUSTMS DISTS)、(1979) 2.25X10+5 GRAMS (PRINCPL CUSTMS DISTS)、General Manufacturing Information: 2H-1-Benzopyran-2-one、4-dihydro-: ACTIVE、Regulatory status of direct food additives: limitations、dihydrocoumarin、synthetic flavor.、Reported uses: non-alcoholic beverages、7.8 ppm、ice cream、ices、etc、21 ppm、candy、44 ppm、baked goods、28 ppm、gelatins and puddings、10 ppm、chewing gum、78 ppm. Regulatory status: FDA status not fully defined、FEMA No 2381.、Useful in vanilla、butter、cream soda、tobacco flavors.、By reduction of coumarin under pressure in presence of nickel at 160-200 °C (Tetralin Gesellschaft、German Patent 355、650) or in presence of palladium-barium sulfate in alcoholic solution (Paal & Schiedewitz、ber Dtsch Chem Ges、63、775、1930). |
登记用途：Uses: Used in perfumes and flavors--has GRAS status in US、[HSDB]、...Used in perfumery industry for its haylike odor.、It has GRAS status and can be used as a food flavor ingredient with a sweet caramel-like taste.、... In woodruff-type flavor compositions.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Methods of Manufacturing: Hydrogenation of coumarin ... with a Raney nickel catalyst under moderate conditions yields 3、4-dihydrocoumarin.、IFRA Fragrance Standards: Dihydrocoumarin、Dihydrocoumarin、1、2-Benzodihydropyrone、2H-1-Benzopyran-2-one、3、4-dihydro-、Chroman-2-one、2-Chromanone、4-Dihydro-2H-1-benzopyran-2-one、o-Hydroxydihydrocinnamic acid lactone、Melilotic acid lactone、Melilotic lactone (commercial name)、IFRA_STD_029.pdf、51、IFRA 51st Amendment - Guidance for the use of IFRA Standards、Restriction: This material should be used only in the limited quantity as stated in the Standard、DERMAL SENSITIZATION AND SYSTEMIC TOXICITY、Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6、materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.、Restriction Limits in the Finished Product (%): 0.038 [Products applied to the lips]、0.011 [Products applied to the axillae]、0.23 [Products applied to the face、body using fingertips]、0.21 [Products related to fine fragrances]、0.053 [Products applied to the body using the hands (palms)、primarily leave-on (Body lotion)]、0.053 [Products applied to the face using the hands (palms)、primarily leave-on (Face moisturizer)]、0.053 [Products applied to the hands using the hands (palms)、primarily leave-on (Hand cream)]、0.018 [Products applied to babies using the hands (palms)、primarily leave-on (Baby cream、oil、talc)]、0.12 [Products with oral and lip exposure]、0.43 [Rinse-off products applied to the hair with some hand contact]、0.43 [Leave-on products applied to the hair with some hand contact]、0.018 [Products with significant anogenital exposure (tampon)]、0.41 [Products with body and hand exposure、primarily rinse off]、1.5 [Household care products with mostly hand contact (excluding aerosol、spray products)]、1.5 [Household care products with mostly hand contact (household aerosol、0.018 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure]、0.018 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure]、No restriction [Other air care products not intended for direct skin contact、minimal or insignificant transfer to skin]、U.S. Production: (1974) 4.5X10+6 G-MAX CONSUMPTION AS FRAGRANCE、(1979) PROBABLY GREATER THAN 1.36X10+6 GRAMS、The U.S. market is estimated at 50 tons、yr.、U.S. Imports: (1977) 2.00X10+5 GRAMS (PRINCPL CUSTMS DISTS)、(1979) 2.25X10+5 GRAMS (PRINCPL CUSTMS DISTS)、General Manufacturing Information: 2H-1-Benzopyran-2-one、4-dihydro-: ACTIVE、Regulatory status of direct food additives: limitations、dihydrocoumarin、synthetic flavor.、Reported uses: non-alcoholic beverages、7.8 ppm、ice cream、ices、etc、21 ppm、candy、44 ppm、baked goods、28 ppm、gelatins and puddings、10 ppm、chewing gum、78 ppm. Regulatory status: FDA status not fully defined、FEMA No 2381.、Useful in vanilla、butter、cream soda、tobacco flavors.、By reduction of coumarin under pressure in presence of nickel at 160-200 °C (Tetralin Gesellschaft、German Patent 355、650) or in presence of palladium-barium sulfate in alcoholic solution (Paal & Schiedewitz、ber Dtsch Chem Ges、63、775、1930).。
3,4-二氢香豆素 是一种化工化合物，登记 CAS 号为 119-84-6，分子式 C9H8O2（分子量 148.16）。
登记 CAS 号：119-84-6
其分子式 C9H8O2 由 9 个碳、8 个氢、2 个氧 组成。
别名/同义词：3,4-二氢香豆素 · dihydrocoumarin · BENZODIHYDROPYRONE
3,4-二氢香豆素 的 CAS 登记号为 119-84-6。
分子式 C9H8O2，分子量 148.16。
别名/同义词：3,4-二氢香豆素、dihydrocoumarin、BENZODIHYDROPYRONE。
登记用途：Uses: Used in perfumes and flavors--has GRAS status in US、[HSDB]、...Used in perfumery industry for its haylike odor.、It has GRAS status and can be used as a food flavor ingredient with a sweet caramel-like taste.、... In woodruff-type flavor compositions.、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Methods of Manufacturing: Hydrogenation of coumarin ... with a Raney nickel catalyst under moderate conditions yields 3、4-dihydrocoumarin.、IFRA Fragrance Standards: Dihydrocoumarin、Dihydrocoumarin、1、2-Benzodihydropyrone、2H-1-Benzopyran-2-one、3、4-dihydro-、Chroman-2-one、2-Chromanone、4-Dihydro-2H-1-benzopyran-2-one、o-Hydroxydihydrocinnamic acid lactone、Melilotic acid lactone、Melilotic lactone (commercial name)、IFRA_STD_029.pdf、51、IFRA 51st Amendment - Guidance for the use of IFRA Standards、Restriction: This material should be used only in the limited quantity as stated in the Standard、DERMAL SENSITIZATION AND SYSTEMIC TOXICITY、Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6、materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.、Restriction Limits in the Finished Product (%): 0.038 [Products applied to the lips]、0.011 [Products applied to the axillae]、0.23 [Products applied to the face、body using fingertips]、0.21 [Products related to fine fragrances]、0.053 [Products applied to the body using the hands (palms)、primarily leave-on (Body lotion)]、0.053 [Products applied to the face using the hands (palms)、primarily leave-on (Face moisturizer)]、0.053 [Products applied to the hands using the hands (palms)、primarily leave-on (Hand cream)]、0.018 [Products applied to babies using the hands (palms)、primarily leave-on (Baby cream、oil、talc)]、0.12 [Products with oral and lip exposure]、0.43 [Rinse-off products applied to the hair with some hand contact]、0.43 [Leave-on products applied to the hair with some hand contact]、0.018 [Products with significant anogenital exposure (tampon)]、0.41 [Products with body and hand exposure、primarily rinse off]、1.5 [Household care products with mostly hand contact (excluding aerosol、spray products)]、1.5 [Household care products with mostly hand contact (household aerosol、0.018 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure]、0.018 [Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure]、No restriction [Other air care products not intended for direct skin contact、minimal or insignificant transfer to skin]、U.S. Production: (1974) 4.5X10+6 G-MAX CONSUMPTION AS FRAGRANCE、(1979) PROBABLY GREATER THAN 1.36X10+6 GRAMS、The U.S. market is estimated at 50 tons、yr.、U.S. Imports: (1977) 2.00X10+5 GRAMS (PRINCPL CUSTMS DISTS)、(1979) 2.25X10+5 GRAMS (PRINCPL CUSTMS DISTS)、General Manufacturing Information: 2H-1-Benzopyran-2-one、4-dihydro-: ACTIVE、Regulatory status of direct food additives: limitations、dihydrocoumarin、synthetic flavor.、Reported uses: non-alcoholic beverages、7.8 ppm、ice cream、ices、etc、21 ppm、candy、44 ppm、baked goods、28 ppm、gelatins and puddings、10 ppm、chewing gum、78 ppm. Regulatory status: FDA status not fully defined、FEMA No 2381.、Useful in vanilla、butter、cream soda、tobacco flavors.、By reduction of coumarin under pressure in presence of nickel at 160-200 °C (Tetralin Gesellschaft、German Patent 355、650) or in presence of palladium-barium sulfate in alcoholic solution (Paal & Schiedewitz、ber Dtsch Chem Ges、63、775、1930).。
3,4-二氢香豆素（CAS 119-84-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 119-84-6 |
|---|---|
| PubChem CID | 660 |
| Molecular formula | C9H8O2 |
| IUPAC name | 3,4-dihydrochromen-2-one |
| UNII (FDA) | NM5K1Y1BT2 |
| FEMA number | 2381 |
| JECFA number | 1171 |
| Molecular Weight | 148.16 |
|---|---|
| XLogP3 | 1.6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 148.052429494 |
| Monoisotopic Mass | 148.052429494 |
| Topological Polar Surface Area | 26.3 |
| Heavy Atom Count | 11 |
| Boiling Point | 522 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 272 °C |
| Boiling Point | 271.00 to 272.00 °C. @ 760.00 mm Hg |
| Melting Point | 77 °F (NTP, 1992) |
| Melting Point | 25 °C |
| Flash Point | 266 °F (NTP, 1992) |
| Flash Point | 130 °C |
| Solubility | 1:2.5-3.5 IN 70% ALCOHOL |
| Solubility | In water, 3,000 mg/l at 37 °C |
| Solubility | 3 mg/mL at 37 °C |
dihydrocoumarin; 3,4-dihydrocoumarin; 119-84-6; hydrocoumarin; Benzodihydropyrone; melilotin; 2-chromanone; 1,2-benzodihydropyrone; melilotic lactone; Melilotine; Oxochroman; 2H-1-Benzopyran-2-one, 3,4-dihydro-; Chroman, 2-oxo-; Dihydrobenzopyrone; Usaf do-12; Coumarin, 3,4-dihydro-
| Regulatory & Food Contact | EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Dairy No safety concern at current levels of intake when used as a flavouring agent |
|---|
| Reported hazard statements | H302, H317 (97.4%) |
|---|
H302 (> 99.9%): Harmful if swallowed [Warning Acute toxicity, oral]
H317 (97.4%): May cause an allergic skin reaction [Warning Sensitization, Skin]
BENZODIHYDROPYRONE · CAS 119-84-6 · C9H8O2. UNII NM5K1Y1BT2. Boiling Point: 522 °F at 760 mmHg (NTP, 1992); Boiling Point: 272 °C; Boiling Point: 271.00 to 272.00 °C. @ 760.00 mm Hg.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: dihydrocoumarin