dextromethorphan hydrobromide

Description

dextromethorphan hydrobromide · CAS 125-69-9 · C18H26BrNO. UNII Z0CG3115FG.

Identification

Computed Descriptors

Physical description & handling notes

• 165.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS Hazard Classification

Documented Uses

• The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (as commonly accompanies the common cold), as well as those resulting from inhaled irritants. In addition, a combination of dextromethorphan and quinidine has been shown to alleviate symptoms of easy laughing and crying (pseudobulbar affect) in patients with amyotrophic lateral sclerosis and multiple sclerosis.
• Breast Feeding; Lactation; Milk, Human; Antitussive Agents
• Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
• Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
• Sigma-1 Agonist [EPC]; Uncompetitive NMDA Receptor Antagonists [MoA]; Sigma-1 Receptor Agonists [MoA]; Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]
• Sigma-1 Agonist [EPC]; Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]; Uncompetitive NMDA Receptor Antagonists [MoA]; Sigma-1 Receptor Agonists [MoA]

Synonyms

Dextromethorphan hydrobromide; 125-69-9; Delsym; Antussan; Demorphan; Tusilan; d-Methorphan hydrobromide; Romilar; Dextromethorphan bromide; Dextromethorphan HBr; Dextromethorphan polistirex; Dextromethorphan hydrobromide anhydrous; Z0CG3115FG; Benylin DM; CHEBI:4471; DTXSID60872346

Frequently Asked Questions

What are the CAS number and molecular formula of dextromethorphan hydrobromide?

CAS 125-69-9; molecular formula C18H26BrNO; molecular weight — g/mol.

What other names is dextromethorphan hydrobromide known by?

Dextromethorphan hydrobromide, 125-69-9, Delsym, Antussan, Demorphan, Tusilan.

Is dextromethorphan hydrobromide classified as hazardous?

0.6% of GHS notifications report no hazard classification (1 of 157).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.