desloratadine (CAS 100643-71-8) — formula C19H19ClN2, molecular weight 310.8.
| CAS Number | 100643-71-8 |
|---|---|
| Molecular Formula | C19H19ClN2 |
| Molecular Weight | 310.8 |
| LogP | 3.2 |
| Applications | Uses: Use (kg, approx.) in Germany (2009): >100, Use (kg) in USA (2002): 1080, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Consumption (g per capita) in the USA (2002): 0.00383, Calculated removal (%): 78.6, For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria. |
Documented applications: Uses: Use (kg, approx.) in Germany (2009): >100, Use (kg) in USA (2002): 1080, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Consumption (g per capita) in the USA (2002): 0.00383, Calculated removal (%): 78.6, For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria..
desloratadine is a chemical compound with CAS registry number 100643-71-8 and molecular formula C19H19ClN2 (molecular weight 310.8).
CAS number: 100643-71-8
Its molecular formula C19H19ClN2 comprises 19 C, 19 H, 1 Cl, 2 N atoms.
Also known as: desloratadine · 地氯雷他定
The CAS registry number of desloratadine is 100643-71-8.
Molecular formula C19H19ClN2, molecular weight 310.8.
It is also registered under: desloratadine, 地氯雷他定.
Recorded applications: Uses: Use (kg, approx.) in Germany (2009): >100, Use (kg) in USA (2002): 1080, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Consumption (g per capita) in the USA (2002): 0.00383, Calculated removal (%): 78.6, For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria..
Independent reference data for desloratadine (CAS 100643-71-8), compiled from public chemistry databases.
| CAS Registry Number | 100643-71-8 |
|---|---|
| PubChem CID | 124087 |
| Molecular formula | C19H19ClN2 |
| IUPAC name | 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene |
| UNII (FDA) | FVF865388R |
| Molecular Weight | 310.8 |
|---|---|
| XLogP3 | 4.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 310.1236763 |
| Monoisotopic Mass | 310.1236763 |
| Topological Polar Surface Area | 24.9 |
| Heavy Atom Count | 22 |
| Solubility | 3.95e-03 g/L |
|---|---|
| LogP | 3.2 |
| LogP | 2.56 |
Desloratadine; 100643-71-8; Clarinex; Aerius; Descarboethoxyloratadine; Desloratidine; Neoclarityn; Azomyr; Sch-34117; Denosin; Opulis; Allex; Sch 34117; 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Actavis; Dasselta
| Reported hazard statements | H302 (90%), H317 (10%), H318 (85%), H361 (74.3%), H411 (89.3%) |
|---|
H302 (90%): Harmful if swallowed [Warning Acute toxicity, oral]
H317 (10%): May cause an allergic skin reaction [Warning Sensitization, Skin]
desloratadine · CAS 100643-71-8 · C19H19ClN2. UNII FVF865388R. Solubility: 3.95e-03 g/L; LogP: 3.2; LogP: 2.56.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 地氯雷他定