des-gly10,(D-his(bzl)6)-lh-rh*ethylamide (CAS 76712-82-8) — formula C66H86N18O12, molecular weight 1323.5.
| CAS Number | 76712-82-8 |
|---|---|
| Molecular Formula | C66H86N18O12 |
| Molecular Weight | 1323.5 |
| LogP | 0.7 |
| Applications | Uses: Palliative treatment of advanced prostate cancer, Treatment of children with central precocious puberty, THERAP CAT: Treatment of central precocious puberty, Methods of Manufacturing: J.E.F. Rivier, W.W. Vale Jr., EP 21620, eidem, US 4244946 (both 1981 to Salk Institute), Formulations, Preparations: Histrelin acetate formulations: Parenteral implants, 50 mg histrelin acetate, Vanta by Valera., General Manufacturing Information: Synthetic nonapeptide agonist analog of LH-RH. |
Documented applications: Uses: Palliative treatment of advanced prostate cancer, Treatment of children with central precocious puberty, THERAP CAT: Treatment of central precocious puberty, Methods of Manufacturing: J.E.F. Rivier, W.W. Vale Jr., EP 21620, eidem, US 4244946 (both 1981 to Salk Institute), Formulations, Preparations: Histrelin acetate formulations: Parenteral implants, 50 mg histrelin acetate, Vanta by Valera., General Manufacturing Information: Synthetic nonapeptide agonist analog of LH-RH..
des-gly10,(D-his(bzl)6)-lh-rh*ethylamide is a chemical compound with CAS registry number 76712-82-8 and molecular formula C66H86N18O12 (molecular weight 1323.5).
CAS number: 76712-82-8
Its molecular formula C66H86N18O12 comprises 66 C, 86 H, 18 N, 12 O atoms.
Also known as: des-gly10,(D-his(bzl)6)-lh-rh*ethylamide · des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺
The CAS registry number of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide is 76712-82-8.
Molecular formula C66H86N18O12, molecular weight 1323.5.
It is also registered under: des-gly10,(D-his(bzl)6)-lh-rh*ethylamide, des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺.
Recorded applications: Uses: Palliative treatment of advanced prostate cancer, Treatment of children with central precocious puberty, THERAP CAT: Treatment of central precocious puberty, Methods of Manufacturing: J.E.F. Rivier, W.W. Vale Jr., EP 21620, eidem, US 4244946 (both 1981 to Salk Institute), Formulations, Preparations: Histrelin acetate formulations: Parenteral implants, 50 mg histrelin acetate, Vanta by Valera., General Manufacturing Information: Synthetic nonapeptide agonist analog of LH-RH..
Independent reference data for des-gly10,(D-his(bzl)6)-lh-rh*ethylamide (CAS 76712-82-8), compiled from public chemistry databases.
| CAS Registry Number | 76712-82-8 |
|---|---|
| PubChem CID | 25077993 |
| Molecular formula | C66H86N18O12 |
| UNII (FDA) | H50H3S3W74 |
| Molecular Weight | 1323.5 |
|---|---|
| XLogP3 | 0.7 |
| Hydrogen Bond Donor Count | 15 |
| Hydrogen Bond Acceptor Count | 15 |
| Rotatable Bond Count | 34 |
| Exact Mass | 1322.66726025 |
| Monoisotopic Mass | 1322.66726025 |
| Topological Polar Surface Area | 449 |
| Heavy Atom Count | 96 |
| Solubility | 10 |
|---|
histrelin; 76712-82-8; Histrelina; Histreline; Histrelinum; ORF 17070; RWJ 17070; ORF-17070; H50H3S3W74; RWJ-17070; ((ImBl)-D-His(sub 6),Pro(sub 9)-NEt)LHRH; ORF 17070RWJ 17070; CHEBI:5739; DTXSID50227543; IBHPE-LHRH; RefChem:56340
| Reported hazard statements | H360 (100%) |
|---|
H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
des-gly10,(D-his(bzl)6)-lh-rh*ethylamide · CAS 76712-82-8 · C66H86N18O12. UNII H50H3S3W74. Solubility: 10.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.