Dasatinib

CAS 302962-49-8C22H26ClN7O2SMW 488.0

Dasatinib (CAS 302962-49-8) — formula C22H26ClN7O2S, molecular weight 488.0.

Product Overview

CAS Number	302962-49-8
Molecular Formula	C22H26ClN7O2S
Molecular Weight	488.0
Melting Point	280-286 °C
LogP	1.8
Applications	Uses: Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 1.9

Applications

Documented applications: Uses: Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 1.9.

Technical Profile

What this product is

Dasatinib is a chemical compound with CAS registry number 302962-49-8 and molecular formula C22H26ClN7O2S (molecular weight 488.0).

Identification

CAS number: 302962-49-8

Its molecular formula C22H26ClN7O2S comprises 22 C, 26 H, 1 Cl, 7 N, 2 O, 1 S atoms.

Also known as: Dasatinib · 达沙替尼

Frequently Asked Questions

What is the CAS number of Dasatinib?

The CAS registry number of Dasatinib is 302962-49-8.

What is the molecular formula and molecular weight of Dasatinib?

Molecular formula C22H26ClN7O2S, molecular weight 488.0.

What other names is Dasatinib known by?

It is also registered under: Dasatinib, 达沙替尼.

What are the documented applications of Dasatinib?

Recorded applications: Uses: Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 1.9.

PubChem Public Data

Independent reference data for Dasatinib (CAS 302962-49-8), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	302962-49-8
PubChem CID	3062316
Molecular formula	C22H26ClN7O2S
IUPAC name	N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
UNII (FDA)	X78UG0A0RN

Computed descriptors

Molecular Weight	488.0
XLogP3	3.6
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	7
Exact Mass	487.1557220
Monoisotopic Mass	487.1557220
Topological Polar Surface Area	135
Heavy Atom Count	33

Physicochemical values on record

Melting Point	280-286 °C
Melting Point	280 - 286 °C
Solubility	1.28e-02 g/L
LogP	1.8
LogP	3.41

Documented uses on record

Synonyms and trade names

Dasatinib; 302962-49-8; Sprycel; BMS-354825; Dasatinib anhydrous; BMS354825; Dasatinib (anhydrous); BMS 354825; dasatinibum; anh. dasatinib; anhydrous dasatinib; dasatinib (anh.); DTXSID4040979; BMS Dasatinib; X78UG0A0RN; NSC732517

GHS hazard classification

Reported hazard statements	H301 (92.5%), H315 (77.5%), H318 (75%), H351 (80%), H360 (12.5%), H361 (80%), H371 (10%), H372 (80%)

H301 (92.5%): Toxic if swallowed [Danger Acute toxicity, oral]

H315 (77.5%): Causes skin irritation [Warning Skin corrosion/irritation]

What the public record says

Dasatinib · CAS 302962-49-8 · C22H26ClN7O2S. UNII X78UG0A0RN. Melting Point: 280-286 °C; Melting Point: 280 - 286 °C; Solubility: 1.28e-02 g/L.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.