达芦那韦

Name: 达芦那韦
Brand: 济南圣和化工有限公司

CAS 206361-99-1C27H37N3O7SMW 547.7

达芦那韦（CAS 206361-99-1）属医药中间体及原料药类产品，分子式 C27H37N3O7S，分子量 547.7。济南圣和化工有限公司常年现货供应该产品，常规纯度按批次COA提供(不公开发布)，可按客户需求安排分装包装，欢迎邮件或来电询价。

产品概览

CAS号	206361-99-1
分子式	C27H37N3O7S
分子量	547.7
熔点	74-76
LogP	1.89
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

达芦那韦在医药中间体及原料药领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：达芦那韦常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除达芦那韦外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

达芦那韦的 CAS 号是多少？

达芦那韦的 CAS 号为 206361-99-1。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

达芦那韦有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Darunavir · CAS 206361-99-1 · C27H37N3O7S. UNII YO603Y8113. Melting Point: 74-76; Melting Point: 74 °C (decomposes); Solubility: 6.68e-02 g/L.

Identification

CAS Registry Number	206361-99-1
PubChem CID	213039
Molecular formula	C27H37N3O7S
IUPAC name	[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
UNII (FDA)	YO603Y8113

Computed Descriptors

Molecular Weight	547.7
XLogP3	2.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	12
Exact Mass	547.23522170
Monoisotopic Mass	547.23522170
Topological Polar Surface Area	149
Heavy Atom Count	38
Formal Charge	0

Physical & Chemical Properties

Melting Point	74-76
Melting Point	74 °C (decomposes)
Solubility	6.68e-02 g/L
LogP	1.89
LogP	1.8

Physical description & handling notes

Solid
White, amorphous solid
Approximately 0.15 mg/mL at
11.43±0.46(Predicted)
Darunavir is an inhibitor of the human immunodeficiency virus (HIV) protease, which prevents HIV viral replication. When administered with ritonavir in combination antiretroviral therapy, darunavir significantly decreases viral load and increases CD4 cell counts, decreasing the morbidity and mortality of HIV infection.
Oral: Tablets, film-coated 300 mg (of darunavir) Prezista (Tibotec); 600 mg (of darunavir) Prezista (Tibotec).

GHS Hazard Classification

Reported hazard statements	H315 (100%), H317 (100%), H319 (100%), H335 (100%)

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

Documented Uses

Inhibitor of the HIV-1 protease
THERAPEUTIC CATEGORY: Antiviral
Use (kg; approx.) in Germany (2009): >750
Consumption (g per capita; approx.) in Germany (2009): 0.00916
Darunavir, co-administered with ritonavir, and with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV) in children age 3 or above and adults with HIV-1 infection.
Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents; Anti-HIV Agents; Anti-Retroviral Agents; HIV Protease Inhibitors

Synonyms

Darunavir; 206361-99-1; TMC114; TMC-114; UIC-94017; Darunavirum; TMC 114; (-)-DARUNAVIR; DTXSID0046779; UIC 94017; CHEBI:367163; TMC-41629; YO603Y8113; DTXCID8026779; Ethanolate, Darunavir; RefChem:585195

Frequently Asked Questions

What are the CAS number and molecular formula of Darunavir?

CAS 206361-99-1; molecular formula C27H37N3O7S; molecular weight — g/mol.

What other names is Darunavir known by?

Darunavir, 206361-99-1, TMC114, TMC-114, UIC-94017, Darunavirum.

Is Darunavir classified as hazardous?

Hazard statements reported: H315, H317, H319, H335.

What are the key physical properties of Darunavir?

Melting Point: 74-76; Melting Point: 74 °C (decomposes); Solubility: 6.68e-02 g/L; LogP: 1.89.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.