dacomitinib (CAS 1110813-31-4) — formula C24H25ClFN5O2, molecular weight 469.9; category pharmaceutical intermediates and APIs.
dacomitinib (CAS 1110813-31-4) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C24H25ClFN5O2 comprises 24 C, 25 H, 1 Cl, 1 F, 5 N, 2 O atoms. Its molecular weight is about 469.9. Reported physicochemical data: melting point around 184-187 ºC, boiling point around 665.7, LogP about 3.92. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 1110813-31-4 |
|---|---|
| Molecular Formula | C24H25ClFN5O2 |
| Molecular Weight | 469.9 |
| Melting Point | 184-187 ºC |
| Boiling Point | 665.7 |
| LogP | 3.92 |
| Category | Pharmaceutical Intermediates & APIs |
dacomitinib is a pharmaceutical intermediate or API compound with CAS registry number 1110813-31-4 and molecular formula C24H25ClFN5O2 (molecular weight 469.9), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 1110813-31-4
Its molecular formula C24H25ClFN5O2 comprises 24 C, 25 H, 1 Cl, 1 F, 5 N, 2 O atoms.
Also known as: dacomitinib · 达克替尼
Category: pharmaceutical intermediates and APIs
The CAS registry number of dacomitinib is 1110813-31-4.
Molecular formula C24H25ClFN5O2, molecular weight 469.9.
It is also registered under: dacomitinib, 达克替尼.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for dacomitinib (CAS 1110813-31-4), compiled from public chemistry databases.
| CAS Registry Number | 1110813-31-4 |
|---|---|
| PubChem CID | 11511120 |
| Molecular formula | C24H25ClFN5O2 |
| IUPAC name | (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide |
| UNII (FDA) | 2XJX250C20 |
| Molecular Weight | 469.9 |
|---|---|
| XLogP3 | 4.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 7 |
| Exact Mass | 469.1680809 |
| Monoisotopic Mass | 469.1680809 |
| Topological Polar Surface Area | 79.4 |
| Heavy Atom Count | 33 |
| Boiling Point | 665.7 |
|---|---|
| Melting Point | 184-187 ºC |
| Solubility | <1 mg/mL |
| LogP | 3.92 |
Dacomitinib; 1110813-31-4; PF-00299804; Dacomitinib anhydrous; dacomitinibum; Vizimpro; PF-299804; 2XJX250C20; pf00299804; PF 00299804-03; PF-00299804-03; (2e)-N-{4-[(3-Chloro-4-Fluorophenyl)amino]-7-Methoxyquinazolin-6-Yl}-4-(Piperidin-1-Yl)but-2-Enamide; CHEBI:132268; DTXSID50149493; (2E)-N-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-METHOXYQUINAZOLIN-6-YL)-4-PIPERIDIN-1-YLBUT-2-ENAMIDE; 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxy-6-quinazolinyl)-4-(1-piperidinyl)-, (2E)-
dacomitinib · CAS 1110813-31-4 · C24H25ClFN5O2. UNII 2XJX250C20. Boiling Point: 665.7; Melting Point: 184-187 ºC; Solubility: <1 mg/mL.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 达克替尼