dabrafenib mesylate (CAS 1195768-06-9) — formula C23H20F3N5O2S2, molecular weight 519.6; category pharmaceutical intermediates and APIs.
dabrafenib mesylate (CAS 1195768-06-9) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C23H20F3N5O2S2 comprises 23 C, 20 H, 3 F, 5 N, 2 O, 2 S atoms. Its molecular weight is about 519.6. Reported physicochemical data: boiling point around 653.7, LogP about 2.9. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 1195768-06-9 |
|---|---|
| Molecular Formula | C23H20F3N5O2S2 |
| Molecular Weight | 519.6 |
| Boiling Point | 653.7 |
| LogP | 2.9 |
| Category | Pharmaceutical Intermediates & APIs |
dabrafenib mesylate is a pharmaceutical intermediate or API compound with CAS registry number 1195768-06-9 and molecular formula C23H20F3N5O2S2 (molecular weight 519.6), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 1195768-06-9
Its molecular formula C23H20F3N5O2S2 comprises 23 C, 20 H, 3 F, 5 N, 2 O, 2 S atoms.
Also known as: dabrafenib mesylate · 甲磺酸达拉非尼
Category: pharmaceutical intermediates and APIs
The CAS registry number of dabrafenib mesylate is 1195768-06-9.
Molecular formula C23H20F3N5O2S2, molecular weight 519.6.
It is also registered under: dabrafenib mesylate, 甲磺酸达拉非尼.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for dabrafenib mesylate (CAS 1195768-06-9), compiled from public chemistry databases.
| CAS Registry Number | 1195768-06-9 |
|---|---|
| PubChem CID | 44462760 |
| Molecular formula | C23H20F3N5O2S2 |
| IUPAC name | N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide |
| UNII (FDA) | QGP4HA4G1B |
| Molecular Weight | 519.6 |
|---|---|
| XLogP3 | 4.8 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 6 |
| Exact Mass | 519.10105173 |
| Monoisotopic Mass | 519.10105173 |
| Topological Polar Surface Area | 147 |
| Heavy Atom Count | 35 |
| Boiling Point | 653.7 |
|---|---|
| LogP | 2.9 |
| Dissociation Constants | -1.5 |
Dabrafenib; 1195765-45-7; GSK2118436A; GSK2118436; GSK-2118436; GSK-2118436A; QGP4HA4G1B; CHEBI:75045; DTXSID20152499; N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide; N-(3-(5-(2-AMINOPYRIMIDIN-4-YL)-2-TERT-BUTYL-1,3-THIAZOL-4-YL)-2-FLUOROPHENYL)-2,6-DIFLUOROBENZENESULFONAMIDE; N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide; dabrafenibum; RefChem:58040; DTXCID8074990; BRAF Inhibitor GSK2118436
| Reported hazard statements | H361 (22.2%), H373 (88.9%), H400 (100%), H410 (11.1%), H411 (88.9%) |
|---|
H361 (22.2%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
H361fd (77.8%): Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]
dabrafenib mesylate · CAS 1195768-06-9 · C23H20F3N5O2S2. UNII QGP4HA4G1B. Boiling Point: 653.7; LogP: 2.9; Dissociation Constants: -1.5.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 甲磺酸达拉非尼