Cortisone

CAS 53-06-5C21H28O5MW 360.4

Cortisone (CAS 53-06-5) — formula C21H28O5, molecular weight 360.4.

Product Overview

CAS Number	53-06-5
Molecular Formula	C21H28O5
Molecular Weight	360.4
Melting Point	222 °C
LogP	1.47

Technical Profile

What this product is

Cortisone is a chemical compound with CAS registry number 53-06-5 and molecular formula C21H28O5 (molecular weight 360.4).

Identification

CAS number: 53-06-5

Its molecular formula C21H28O5 comprises 21 C, 28 H, 5 O atoms.

Also known as: Cortisone · 可的松

Frequently Asked Questions

What is the CAS number of Cortisone?

The CAS registry number of Cortisone is 53-06-5.

What is the molecular formula and molecular weight of Cortisone?

Molecular formula C21H28O5, molecular weight 360.4.

What other names is Cortisone known by?

It is also registered under: Cortisone, 可的松.

PubChem Public Data

Independent reference data for Cortisone (CAS 53-06-5), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	53-06-5
PubChem CID	222786
Molecular formula	C21H28O5
IUPAC name	(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
UNII (FDA)	V27W9254FZ

Computed descriptors

Molecular Weight	360.4
XLogP3	1.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	360.19367399
Monoisotopic Mass	360.19367399
Topological Polar Surface Area	91.7
Heavy Atom Count	26

Physicochemical values on record

Melting Point	222 °C
Solubility	0.28 mg/mL at 25 °C
LogP	1.47
LogP	1.64
Collision Cross Section	191.4 Å² [M-H]-
Collision Cross Section	213.5 Å² [M+Na]+
Collision Cross Section	188.4 Å² [M+H]+

Documented uses on record

Synonyms and trade names

cortisone; 53-06-5; Kendall's compound E; Reichstein's substance FA; Wintersteiner's compound F; 17-Hydroxy-11-dehydrocorticosterone; 11-Dehydro-17-hydroxycorticosterone; Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-; Cortisona; Cortisonum; Kortison; 4-Pregnene-17alpha,21-diol-3,11,20-trione; 17alpha,21-Dihydroxypregn-4-ene-3,11,20-trione; DTXSID5022857; Pregn-4-en-17alpha,21-diol-3,11,20-trione; 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione

GHS hazard classification

Reported hazard statements	H361 (98%)

H361 (98%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

What the public record says

Cortisone · CAS 53-06-5 · C21H28O5. UNII V27W9254FZ. Melting Point: 222 °C; Solubility: 0.28 mg/mL at 25 °C; LogP: 1.47.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.