Cortisone (CAS 53-06-5) — formula C21H28O5, molecular weight 360.4; category pharmaceutical intermediates and APIs.
Cortisone (CAS 53-06-5) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C21H28O5 comprises 21 C, 28 H, 5 O atoms. Its molecular weight is about 360.4. Reported physicochemical data: melting point around 222 °C, LogP about 1.47. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 53-06-5 |
|---|---|
| Molecular Formula | C21H28O5 |
| Molecular Weight | 360.4 |
| Melting Point | 222 °C |
| LogP | 1.47 |
| Applications | Calculated removal (%): 45.8, Pharmaceuticals |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Calculated removal (%): 45.8, Pharmaceuticals.
Cortisone is a pharmaceutical intermediate or API compound with CAS registry number 53-06-5 and molecular formula C21H28O5 (molecular weight 360.4), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 53-06-5
Its molecular formula C21H28O5 comprises 21 C, 28 H, 5 O atoms.
Also known as: Cortisone · 可的松
Category: pharmaceutical intermediates and APIs
The CAS registry number of Cortisone is 53-06-5.
Molecular formula C21H28O5, molecular weight 360.4.
It is also registered under: Cortisone, 可的松.
Recorded applications: Calculated removal (%): 45.8, Pharmaceuticals.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Cortisone (CAS 53-06-5), compiled from public chemistry databases.
| CAS Registry Number | 53-06-5 |
|---|---|
| PubChem CID | 222786 |
| Molecular formula | C21H28O5 |
| IUPAC name | (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione |
| UNII (FDA) | V27W9254FZ |
| Molecular Weight | 360.4 |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 360.19367399 |
| Monoisotopic Mass | 360.19367399 |
| Topological Polar Surface Area | 91.7 |
| Heavy Atom Count | 26 |
| Melting Point | 222 °C |
|---|---|
| Solubility | 0.28 mg/mL at 25 °C |
| LogP | 1.47 |
| LogP | 1.64 |
| Collision Cross Section | 191.4 Ų [M-H]- |
| Collision Cross Section | 213.5 Ų [M+Na]+ |
| Collision Cross Section | 188.4 Ų [M+H]+ |
cortisone; 53-06-5; Kendall's compound E; Reichstein's substance FA; Wintersteiner's compound F; 17-Hydroxy-11-dehydrocorticosterone; 11-Dehydro-17-hydroxycorticosterone; Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-; Cortisona; Cortisonum; Kortison; 4-Pregnene-17alpha,21-diol-3,11,20-trione; 17alpha,21-Dihydroxypregn-4-ene-3,11,20-trione; DTXSID5022857; Pregn-4-en-17alpha,21-diol-3,11,20-trione; 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione
| Reported hazard statements | H361 (98%) |
|---|
H361 (98%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
Cortisone · CAS 53-06-5 · C21H28O5. UNII V27W9254FZ. Melting Point: 222 °C; Solubility: 0.28 mg/mL at 25 °C; LogP: 1.47.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 可的松