Combretastatin A-4

CAS 117048-59-6C18H20O5MW 316.3

Combretastatin A-4 (CAS 117048-59-6) — formula C18H20O5, molecular weight 316.3.

Product Overview

CAS Number	117048-59-6
Molecular Formula	C18H20O5
Molecular Weight	316.3
LogP	3.7

Technical Profile

What this product is

Combretastatin A-4 is a chemical compound with CAS registry number 117048-59-6 and molecular formula C18H20O5 (molecular weight 316.3).

Identification

CAS number: 117048-59-6

Its molecular formula C18H20O5 comprises 18 C, 20 H, 5 O atoms.

Also known as: Combretastatin A-4 · 考布他汀A-4

Frequently Asked Questions

What is the CAS number of Combretastatin A-4?

The CAS registry number of Combretastatin A-4 is 117048-59-6.

What is the molecular formula and molecular weight of Combretastatin A-4?

Molecular formula C18H20O5, molecular weight 316.3.

What other names is Combretastatin A-4 known by?

It is also registered under: Combretastatin A-4, 考布他汀A-4.

PubChem Public Data

Independent reference data for Combretastatin A-4 (CAS 117048-59-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	117048-59-6
PubChem CID	5351344
Molecular formula	C18H20O5
IUPAC name	2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
UNII (FDA)	16U6OP69RQ

Computed descriptors

Molecular Weight	316.3
XLogP3	3.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	316.13107373
Monoisotopic Mass	316.13107373
Topological Polar Surface Area	57.2
Heavy Atom Count	23

Documented uses on record

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
Combretastatin A4 has known human metabolites that include (2S,3S,4S,5R)-3,4,5-trihydroxy-6-[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]oxane-2-carboxylic acid.

Synonyms and trade names

Combretastatin A4; 117048-59-6; Combretastatin A-4; Combrestatin A4; Combretastatin 4; 2'-deoxycombretastatin A1; 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol; NSC-613729; 16U6OP69RQ; 3,4,5-Trimethoxy-3'-hydroxy-4'-methoxystilbene; 1-(3,4,5-Trimethoxyphenyl)-2-(3'-hydroxy-4'-methoxyphenyl)ethene; DTXSID101025983; Phenol, 2-methoxy-5-(2-(3,4,5-trimethoxyphenyl)ethenyl)-, (Z)-; NSC613729; 2-methoxy-5-((Z)-2-(3,4,5-trimethoxyphenyl)ethenyl)phenol; RefChem:918948

GHS hazard classification

Reported hazard statements	H301 (100%), H311 (100%), H318 (100%), H331 (100%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H311 (100%): Toxic in contact with skin [Danger Acute toxicity, dermal]

What the public record says

Combretastatin A-4 · CAS 117048-59-6 · C18H20O5. UNII 16U6OP69RQ.

Source: PubChem / Wikidata; the batch COA governs where values differ.