多粘菌素e（CAS 1066-17-7）：分子式 C52H98N16O13、分子量 1155.4。
| CAS号 | 1066-17-7 |
|---|---|
| 分子式 | C52H98N16O13 |
| 分子量 | 1155.4 |
| 熔点 | 200-220 °C |
| LogP | -2.4 |
| 应用领域 | Uses: An antibiotic mixture containing mainly colistins A and B、[Merck Index] Acts as a detergent on cell membranes、[ChemIDplus] A polypeptide antibiotic produced by soil microbes、[Hawley]、MEDICATION、MEDICATION (VET)、Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes、Methods of Manufacturing: Cyclopolypeptide antibiotic produced by Bacillus colistinus (Aerobacillus colistinus) isolated soil.、Antibiotic produced by a soil microorganism.、Formulations、Preparations: COLISTIMETHATE SODIUM、USP (COLY-MYCIN M PARENTERAL)、IS MARKETED FOR IV OR IM INJECTION IN VIALS CONTAINING EQUIV OF 20 OR 150 MG OF COLISTIN BASE TO BE RECONSTITUTED TO CONTAIN 10 OR 75 MG、ML、RESPECTIVELY.、COLISTIMETHATE SODIUM、COLISTIN SULFATE FOR ORAL SUSPENSION、USP (COLY-MYCIN S ORAL SUSPENSION) MARKETED AS POWDER (300 MG) TO BE SUSPENDED IN DISTILLED WATER PRIOR TO DISPENSING (5 MG、ML).、COLISTIN SULFATE、COLISTIN IS AVAILABLE FOR CLINICAL USE AS COLISTIN SULFATE、FOR ORAL USE、& COLISTIMETHATE SODIUM (COLISTIN SODIUM METHANESULFONATE)、A PARENTERAL PREPN.、Composed of colistins A、B、and C.、General Manufacturing Information: COLISTIN IS IDENTICAL TO POLYMYXIN B EXCEPT FOR SUBSTITUTION OF RESIDUE OF D-LEUCINE FOR THAT OF D-PHENYLALANINE.、VET APPLICATIONS: IN CALF SCOURS、IN RESP & UROGENITAL INFECTIONS IN CATS & DOGS、& ESPECIALLY PSEUDOMONAS AEROGINOSA INFECTIONS. OFTEN USED WITH CHLORAMPHENICOL. SYNERGISTIC WITH TRIMETHOPRIM.、WARNING: IN FRANCE、RUSSIA、& SOME RUSSIAN SATELLITE COUNTRIES THE WORD "COLLMYCIN" FREQUENTLY REFERS TO ANTIBIOTIC NEOMYCIN & NOT COLISTIN. ELSEWHERE、COLIMYCIN IS COLISTIN. ... AN INJECTABLE FORM、SODIUM COLISTIMETHANESULFONATE、IS KNOWN BY GENERIC NAME COLISTIMETHATE SODIUM.、SEPARATION INTO POLYMYXINS E1 & E2 & IDENTITY OF COLISTIN A WITH POLYMYXIN E1: WILKINSON、LOWE、J CHEM SOC 1964、4107. SYNTHESIS COLISTIN A: STUDER ET AL、HELV CHIM ACTA 48、1371 (1965).、For more General Manufacturing Information (Complete) data for COLISTIN (6 total)、please visit the HSDB record page. |
登记用途：Uses: An antibiotic mixture containing mainly colistins A and B、[Merck Index] Acts as a detergent on cell membranes、[ChemIDplus] A polypeptide antibiotic produced by soil microbes、[Hawley]、MEDICATION、MEDICATION (VET)、Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes、Methods of Manufacturing: Cyclopolypeptide antibiotic produced by Bacillus colistinus (Aerobacillus colistinus) isolated soil.、Antibiotic produced by a soil microorganism.、Formulations、Preparations: COLISTIMETHATE SODIUM、USP (COLY-MYCIN M PARENTERAL)、IS MARKETED FOR IV OR IM INJECTION IN VIALS CONTAINING EQUIV OF 20 OR 150 MG OF COLISTIN BASE TO BE RECONSTITUTED TO CONTAIN 10 OR 75 MG、ML、RESPECTIVELY.、COLISTIMETHATE SODIUM、COLISTIN SULFATE FOR ORAL SUSPENSION、USP (COLY-MYCIN S ORAL SUSPENSION) MARKETED AS POWDER (300 MG) TO BE SUSPENDED IN DISTILLED WATER PRIOR TO DISPENSING (5 MG、ML).、COLISTIN SULFATE、COLISTIN IS AVAILABLE FOR CLINICAL USE AS COLISTIN SULFATE、FOR ORAL USE、& COLISTIMETHATE SODIUM (COLISTIN SODIUM METHANESULFONATE)、A PARENTERAL PREPN.、Composed of colistins A、B、and C.、General Manufacturing Information: COLISTIN IS IDENTICAL TO POLYMYXIN B EXCEPT FOR SUBSTITUTION OF RESIDUE OF D-LEUCINE FOR THAT OF D-PHENYLALANINE.、VET APPLICATIONS: IN CALF SCOURS、IN RESP & UROGENITAL INFECTIONS IN CATS & DOGS、& ESPECIALLY PSEUDOMONAS AEROGINOSA INFECTIONS. OFTEN USED WITH CHLORAMPHENICOL. SYNERGISTIC WITH TRIMETHOPRIM.、WARNING: IN FRANCE、RUSSIA、& SOME RUSSIAN SATELLITE COUNTRIES THE WORD "COLLMYCIN" FREQUENTLY REFERS TO ANTIBIOTIC NEOMYCIN & NOT COLISTIN. ELSEWHERE、COLIMYCIN IS COLISTIN. ... AN INJECTABLE FORM、SODIUM COLISTIMETHANESULFONATE、IS KNOWN BY GENERIC NAME COLISTIMETHATE SODIUM.、SEPARATION INTO POLYMYXINS E1 & E2 & IDENTITY OF COLISTIN A WITH POLYMYXIN E1: WILKINSON、LOWE、J CHEM SOC 1964、4107. SYNTHESIS COLISTIN A: STUDER ET AL、HELV CHIM ACTA 48、1371 (1965).、For more General Manufacturing Information (Complete) data for COLISTIN (6 total)、please visit the HSDB record page.。
多粘菌素e 是一种化工化合物，登记 CAS 号为 1066-17-7，分子式 C52H98N16O13（分子量 1155.4）。
登记 CAS 号：1066-17-7
其分子式 C52H98N16O13 由 52 个碳、98 个氢、16 个氮、13 个氧 组成。
别名/同义词：多粘菌素e · COLISTIN
多粘菌素e 的 CAS 登记号为 1066-17-7。
分子式 C52H98N16O13，分子量 1155.4。
别名/同义词：多粘菌素e、COLISTIN。
登记用途：Uses: An antibiotic mixture containing mainly colistins A and B、[Merck Index] Acts as a detergent on cell membranes、[ChemIDplus] A polypeptide antibiotic produced by soil microbes、[Hawley]、MEDICATION、MEDICATION (VET)、Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes、Methods of Manufacturing: Cyclopolypeptide antibiotic produced by Bacillus colistinus (Aerobacillus colistinus) isolated soil.、Antibiotic produced by a soil microorganism.、Formulations、Preparations: COLISTIMETHATE SODIUM、USP (COLY-MYCIN M PARENTERAL)、IS MARKETED FOR IV OR IM INJECTION IN VIALS CONTAINING EQUIV OF 20 OR 150 MG OF COLISTIN BASE TO BE RECONSTITUTED TO CONTAIN 10 OR 75 MG、ML、RESPECTIVELY.、COLISTIMETHATE SODIUM、COLISTIN SULFATE FOR ORAL SUSPENSION、USP (COLY-MYCIN S ORAL SUSPENSION) MARKETED AS POWDER (300 MG) TO BE SUSPENDED IN DISTILLED WATER PRIOR TO DISPENSING (5 MG、ML).、COLISTIN SULFATE、COLISTIN IS AVAILABLE FOR CLINICAL USE AS COLISTIN SULFATE、FOR ORAL USE、& COLISTIMETHATE SODIUM (COLISTIN SODIUM METHANESULFONATE)、A PARENTERAL PREPN.、Composed of colistins A、B、and C.、General Manufacturing Information: COLISTIN IS IDENTICAL TO POLYMYXIN B EXCEPT FOR SUBSTITUTION OF RESIDUE OF D-LEUCINE FOR THAT OF D-PHENYLALANINE.、VET APPLICATIONS: IN CALF SCOURS、IN RESP & UROGENITAL INFECTIONS IN CATS & DOGS、& ESPECIALLY PSEUDOMONAS AEROGINOSA INFECTIONS. OFTEN USED WITH CHLORAMPHENICOL. SYNERGISTIC WITH TRIMETHOPRIM.、WARNING: IN FRANCE、RUSSIA、& SOME RUSSIAN SATELLITE COUNTRIES THE WORD "COLLMYCIN" FREQUENTLY REFERS TO ANTIBIOTIC NEOMYCIN & NOT COLISTIN. ELSEWHERE、COLIMYCIN IS COLISTIN. ... AN INJECTABLE FORM、SODIUM COLISTIMETHANESULFONATE、IS KNOWN BY GENERIC NAME COLISTIMETHATE SODIUM.、SEPARATION INTO POLYMYXINS E1 & E2 & IDENTITY OF COLISTIN A WITH POLYMYXIN E1: WILKINSON、LOWE、J CHEM SOC 1964、4107. SYNTHESIS COLISTIN A: STUDER ET AL、HELV CHIM ACTA 48、1371 (1965).、For more General Manufacturing Information (Complete) data for COLISTIN (6 total)、please visit the HSDB record page.。
多粘菌素e（CAS 1066-17-7）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 1066-17-7 |
|---|---|
| PubChem CID | 5311054 |
| 分子式 | C52H98N16O13 |
| UNII（FDA） | Z67X93HJG1 |
| Molecular Weight | 1155.4 |
|---|---|
| XLogP3 | -3.3 |
| Hydrogen Bond Donor Count | 18 |
| Hydrogen Bond Acceptor Count | 18 |
| Rotatable Bond Count | 28 |
| Exact Mass | 1154.74992724 |
| Monoisotopic Mass | 1154.74992724 |
| Topological Polar Surface Area | 491 |
| Heavy Atom Count | 81 |
| Melting Point | 200-220 °C |
|---|---|
| Melting Point | 200 - 220 °C |
| Solubility | 564000 |
| Solubility | 2.38e-01 g/L |
| LogP | -2.4 |
colistin; 1066-17-7; Colomycin; Colymysin S; Z67X93HJG1; Colisticin; Sogecoli; Polymixin E; RefChem:578510; DTXSID1040663; CHEBI:37943; 213-907-3; Colisticina; Colistina; Colistinum; Kangdisu
| 法规与食品接触 | ANTIMICROBIAL_AGENT: Veterinary Drug 0-7 µg/kg bw/d TRS 939-JECFA 66/18 FAS 57-JECFA66/3 |
|---|
多粘菌素e · CAS 1066-17-7 · C52H98N16O13. UNII Z67X93HJG1. Melting Point: 200-220 °C; Melting Point: 200 - 220 °C; Solubility: 564000.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: COLISTIN