氯唑西林

CAS 61-72-3C19H18ClN3O5SMW 435.9

氯唑西林（CAS 61-72-3）：分子式 C19H18ClN3O5S、分子量 435.9。

产品概览

CAS号	61-72-3
分子式	C19H18ClN3O5S
分子量	435.9
LogP	2.48
应用领域	Uses: MEDICATION、Methods of Manufacturing: 6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt、Sodium Cloxacillin USP、General Manufacturing Information: NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS.、MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI.、PENICILLINS、...SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS、MILK、OR EGGS DESTINED FOR HUMAN USE...CURRENTLY PERMITTING 0.05 PPM FOR ITS NEGLIGIBLE RESIDUE IN UNCOOKED EDIBLE TISSUES OF CATTLE.、PROPERTIES & PHARMACOLOGY: NAYLOR ET AL、NATURE 195、1264 (1962).

应用领域

登记用途：Uses: MEDICATION、Methods of Manufacturing: 6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt、Sodium Cloxacillin USP、General Manufacturing Information: NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS.、MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI.、PENICILLINS、...SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS、MILK、OR EGGS DESTINED FOR HUMAN USE...CURRENTLY PERMITTING 0.05 PPM FOR ITS NEGLIGIBLE RESIDUE IN UNCOOKED EDIBLE TISSUES OF CATTLE.、PROPERTIES & PHARMACOLOGY: NAYLOR ET AL、NATURE 195、1264 (1962).。

技术档案

这个产品是什么

氯唑西林是一种化工化合物，登记 CAS 号为 61-72-3，分子式 C19H18ClN3O5S（分子量 435.9）。

识别信息

登记 CAS 号：61-72-3

其分子式 C19H18ClN3O5S 由 19 个碳、18 个氢、1 个氯、3 个氮、5 个氧、1 个硫组成。

别名/同义词：氯唑西林 · cloxacillin

常见问题

氯唑西林的 CAS 号是多少？

氯唑西林的 CAS 登记号为 61-72-3。

氯唑西林的分子式与分子量是多少？

分子式 C19H18ClN3O5S，分子量 435.9。

氯唑西林还有哪些别名？

别名/同义词：氯唑西林、cloxacillin。

氯唑西林的登记用途是什么？

PubChem 公开数据

氯唑西林（CAS 61-72-3）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number	61-72-3
PubChem CID	6098
Molecular formula	C19H18ClN3O5S
IUPAC name	(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
UNII (FDA)	O6X5QGC2VB

计算分子描述符

Molecular Weight	435.9
XLogP3	2.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	4
Exact Mass	435.0655696
Monoisotopic Mass	435.0655696
Topological Polar Surface Area	138
Heavy Atom Count	29

在册的理化数值

Solubility	5.32e-02 g/L
LogP	2.48
LogP	LogP = 2.44
LogP	2.86
Dissociation Constants	2.78
Collision Cross Section	200.94 Å² [M-H]-

在册的记载用途

同义词与商品名

cloxacillin; 61-72-3; Cloxacilline; Cloxacillinum; Cloxacilina; Methocillin S; Syntarpen; Clossacillina; Chloroxacillin; O6X5QGC2VB; (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin; CHEBI:49566; 6-(3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid; cloxacillina; Cloxacillin, Sodium; Sodium, Cloxacillin

GHS 危害分类

Reported hazard statements	H315 (85.4%), H317 (91.7%), H319 (85.4%), H334 (97.9%), H335 (85.4%)

H315 (85.4%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (91.7%): May cause an allergic skin reaction [Warning Sensitization, Skin]

公开数据库对它的描述

cloxacillin · CAS 61-72-3 · C19H18ClN3O5S. UNII O6X5QGC2VB. Solubility: 5.32e-02 g/L; LogP: 2.48; LogP: LogP = 2.44.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。