氯倍他索（CAS 25122-41-2）：分子式 C22H28ClFO4、分子量 410.9。
| CAS号 | 25122-41-2 |
|---|---|
| 分子式 | C22H28ClFO4 |
| 分子量 | 410.9 |
| 熔点 | 195.5 - 197 °C |
| LogP | log Kow = 2.48 |
| 应用领域 | Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >10、Use (kg) in USA (2002): 50、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Consumption (g per capita) in the USA (2002): 0.000177、Calculated removal (%): 3、Methods of Manufacturing: Preparation: Elks et al.、DE 1902340、eidem、US 3721687 (1969、1973 both to Glaxo)、Formulations、Preparations: Table: Clobetasol Propionate Preparations [Table#7933] |
登记用途：Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >10、Use (kg) in USA (2002): 50、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Consumption (g per capita) in the USA (2002): 0.000177、Calculated removal (%): 3、Methods of Manufacturing: Preparation: Elks et al.、DE 1902340、eidem、US 3721687 (1969、1973 both to Glaxo)、Formulations、Preparations: Table: Clobetasol Propionate Preparations [Table#7933]。
氯倍他索 是一种化工化合物，登记 CAS 号为 25122-41-2，分子式 C22H28ClFO4（分子量 410.9）。
登记 CAS 号：25122-41-2
其分子式 C22H28ClFO4 由 22 个碳、28 个氢、1 个氯、1 个氟、4 个氧 组成。
别名/同义词：氯倍他索 · Clobetasol
氯倍他索 的 CAS 登记号为 25122-41-2。
分子式 C22H28ClFO4，分子量 410.9。
别名/同义词：氯倍他索、Clobetasol。
登记用途：Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >10、Use (kg) in USA (2002): 50、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Consumption (g per capita) in the USA (2002): 0.000177、Calculated removal (%): 3、Methods of Manufacturing: Preparation: Elks et al.、DE 1902340、eidem、US 3721687 (1969、1973 both to Glaxo)、Formulations、Preparations: Table: Clobetasol Propionate Preparations [Table#7933]。
氯倍他索（CAS 25122-41-2）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 25122-41-2 |
|---|---|
| PubChem CID | 5311051 |
| Molecular formula | C22H28ClFO4 |
| IUPAC name | (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
| UNII (FDA) | ADN79D536H |
| Molecular Weight | 410.9 |
|---|---|
| XLogP3 | 2.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 410.1660152 |
| Monoisotopic Mass | 410.1660152 |
| Topological Polar Surface Area | 74.6 |
| Heavy Atom Count | 28 |
| Melting Point | 195.5 - 197 °C |
|---|---|
| Solubility | 1.42e-02 g/L |
| LogP | log Kow = 2.48 |
| LogP | 2.48 |
clobetasol; 25122-41-2; Clobetasolum; DTXSID2048955; Clobecort Amex; 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione; ADN79D536H; (11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; DTXCID9028881; CHEBI:205919; Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11beta,16beta)-; clobetasolo; Clofenazon; RefChem:54853; D07AD01; 246-633-8
| Reported hazard statements | H360 (94.8%), H373 (98.3%), H413 (94.8%) |
|---|
H360 (94.8%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H373 (98.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
Clobetasol · CAS 25122-41-2 · C22H28ClFO4. UNII ADN79D536H. Melting Point: 195.5 - 197 °C; Solubility: 1.42e-02 g/L; LogP: log Kow = 2.48.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Clobetasol