Cisapride

Description

Cisapride · CAS 86718-70-9 · C23H29ClFN3O4. UNII UVL329170W. Melting Point: 110; Melting Point: 110 °C; Solubility: 2.71.

Identification

CAS Registry Number	86718-70-9
PubChem CID	6917698
Molecular formula	C23H29ClFN3O4
IUPAC name	4-amino-5-chloro-N-[(3S,4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
UNII (FDA)	UVL329170W

Computed Descriptors

Molecular Weight	465.9
XLogP3	3.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Exact Mass	465.1830623
Monoisotopic Mass	465.1830623
Topological Polar Surface Area	86.1
Heavy Atom Count	32
Formal Charge	0

Physical & Chemical Properties

Melting Point	110
Melting Point	110 °C
Solubility	2.71
Solubility	1.20e-02 g/L
LogP	3.3
Other Experimental Properties	109.8 °C /monohydrate/

Physical description & handling notes

• Solid
• White to slightly biege powder
• Odorless
• Sparingly soluble in methanol. Soluble in acetone
• Practically insoluble in water.
• Crystals from 2-propanol /monohydrate/

GHS Hazard Classification

Reported hazard statements	H318 (100%)

Documented Uses

• For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
• Breast Feeding; Lactation; Gastrointestinal Agents; Serotonin Agonists;
• Cisapride (Class: Other Substances, Added Date: 12-1999)
• Anti-Ulcer Agents; Gastrointestinal Agents; Serotonin Agonists
• Cisapride is indicated for the symptomatic treatment of nocturnal (and daytime /Not included in US product labeling/) heartburn, and of esophagitis due to reflux and delayed gastric emptying. Treatment may continue for up to 8 weeks; however, tolerance to cisapride may develop at some point in therapy. /Included in US product labeling/
• Cisapride is indicated in the treatment of gastroparesis, including idiopathic, diabetic, and intestinal pseudo-obstruction. Treatment may continue for up to 8 weeks; however, tolerance to cisapride may develop at some point in therapy. /NOT included in US product labeling/

Synonyms

cisapride; 81098-60-4; Cisaprida; Cisapridum; Enteropride; Kinestase; Pridesia; Prepulsid; R 51619; CHEBI:3720; UVL329170W; 4-amino-5-chloro-N-[(3S,4R)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide; cis-4-Amino-5-chloro-N-(1-(3-(p-fluorophenoxy)propyl)-3-methoxy-4-piperidyl)-o-anisamide; R-51,619; R-51619; Benzamide, 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinyl)-2-methoxy-, cis-

Frequently Asked Questions

What are the CAS number and molecular formula of Cisapride?

CAS 86718-70-9; molecular formula C23H29ClFN3O4; molecular weight — g/mol.

What other names is Cisapride known by?

cisapride, 81098-60-4, Cisaprida, Cisapridum, Enteropride, Kinestase.

Is Cisapride classified as hazardous?

Hazard statements reported: H318.

What are the key physical properties of Cisapride?

Melting Point: 110; Melting Point: 110 °C; Solubility: 2.71; Solubility: 1.20e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.