西多福韦

Name: 西多福韦
Brand: 济南圣和化工有限公司

CAS 113852-37-2C8H14N3O6PMW 279.19

本页收录西多福韦，CAS 登记号为 113852-37-2，分子式 C8H14N3O6P，分子量 279.19，归类于医药中间体及原料药。作为主营产品之一，济南圣和化工有限公司可提供从公斤级到吨级的稳定供货，随货附 COA 与质检资料。

产品概览

CAS号	113852-37-2
分子式	C8H14N3O6P
分子量	279.19
熔点	480
LogP	-3.9
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

该产品的下游应用集中在医药中间体及原料药。不同客户工艺差异较大，我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：西多福韦常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除西多福韦外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

西多福韦的 CAS 号是多少？

西多福韦的 CAS 号为 113852-37-2。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

西多福韦有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Cidofovir · CAS 113852-37-2 · C8H14N3O6P. UNII 768M1V522C. Melting Point: 480; Melting Point: 260 °C (dec); Melting Point: 480 °C.

Identification

CAS Registry Number	113852-37-2
PubChem CID	60613
Molecular formula	C8H14N3O6P
IUPAC name	[(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid
UNII (FDA)	768M1V522C

Computed Descriptors

Molecular Weight	279.19
XLogP3	-3.6
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	279.06202217
Monoisotopic Mass	279.06202217
Topological Polar Surface Area	146
Heavy Atom Count	18
Formal Charge	0

Physical & Chemical Properties

Melting Point	480
Melting Point	260 °C (dec)
Melting Point	480 °C
Solubility	=170 mg/mL at pH 6-8
Solubility	1.15e+01 g/L
LogP	-3.9
LogP	-3.17

Physical description & handling notes

Solid
Fluffy white powder
White crystalline powder
Aqueous solubility >=170 mg/ml @ pH 6-8
log Kow = -3.3 @ pH 7.1
It is recommended that cidofovir admixtures be administered within 24 hours of preparation and that refrigeration or freezer storage not be used to extend this 24 hour limit.

Documented Uses

Preparation: A. Holy et al., EP 253412; eidem, US 5142051 (1988, 1992 both to Ceskoslov. Akad, Ved; Rega Inst.) ... .
For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS)
Cidofovir is a nucleoside analogue and antiviral agent which is used in therapy of serious cytomegalovirus infections in immunocompromised patients. Cidofovir has been associated with mild-to-moderate serum aminotransferase elevations during intravenous therapy, but has not been convincingly linked to cases of clinically apparent acute liver injury.
Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents
Cidofovir is used for the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS).
Cidofovir has been used for the management of acyclovir-resistant herpes simplex virus (HSV-1 and HSV-2) infections in immunocompromised patients.

Synonyms

Cidofovir; 113852-37-2; Vistide; HPMPC; Cidofovir anhydrous; (S)-HPMPC; anhydrous cidofovir; GS-504; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; DTXSID3043734; GS 0504; GS504; GS-0504; 768M1V522C; NSC-742135; 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine

Frequently Asked Questions

What are the CAS number and molecular formula of Cidofovir?

CAS 113852-37-2; molecular formula C8H14N3O6P; molecular weight — g/mol.

What other names is Cidofovir known by?

Cidofovir, 113852-37-2, Vistide, HPMPC, Cidofovir anhydrous, (S)-HPMPC.

What are the key physical properties of Cidofovir?

Melting Point: 480; Melting Point: 260 °C (dec); Melting Point: 480 °C; Solubility: =170 mg/mL at pH 6-8.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.