Cetirizine (CAS 83881-51-0) — formula C21H25ClN2O3, molecular weight 388.9; category pharmaceutical intermediates and APIs.
Cetirizine (CAS 83881-51-0) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C21H25ClN2O3 comprises 21 C, 25 H, 1 Cl, 2 N, 3 O atoms. Its molecular weight is about 388.9. Reported physicochemical data: melting point around 110-115°C, boiling point around 542.1, LogP about 2.8. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 83881-51-0 |
|---|---|
| Molecular Formula | C21H25ClN2O3 |
| Molecular Weight | 388.9 |
| Melting Point | 110-115°C |
| Boiling Point | 542.1 |
| LogP | 2.8 |
| Applications | A second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma, THERAP CAT: Antihistaminic, Use (kg) in Switzerland (2009): >100, Use (kg |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: A second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma, THERAP CAT: Antihistaminic, Use (kg) in Switzerland (2009): >100, Use (kg.
Cetirizine is a pharmaceutical intermediate or API compound with CAS registry number 83881-51-0 and molecular formula C21H25ClN2O3 (molecular weight 388.9), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 83881-51-0
Its molecular formula C21H25ClN2O3 comprises 21 C, 25 H, 1 Cl, 2 N, 3 O atoms.
Also known as: Cetirizine · 西替利嗪
Category: pharmaceutical intermediates and APIs
The CAS registry number of Cetirizine is 83881-51-0.
Molecular formula C21H25ClN2O3, molecular weight 388.9.
It is also registered under: Cetirizine, 西替利嗪.
Recorded applications: A second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma, THERAP CAT: Antihistaminic, Use (kg) in Switzerland (2009): >100, Use (kg.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Cetirizine (CAS 83881-51-0), compiled from public chemistry databases.
| CAS Registry Number | 83881-51-0 |
|---|---|
| PubChem CID | 2678 |
| Molecular formula | C21H25ClN2O3 |
| IUPAC name | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid |
| UNII (FDA) | YO7261ME24 |
| Molecular Weight | 388.9 |
|---|---|
| XLogP3 | 1.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 8 |
| Exact Mass | 388.1553704 |
| Monoisotopic Mass | 388.1553704 |
| Topological Polar Surface Area | 53 |
| Heavy Atom Count | 27 |
| Boiling Point | 542.1 |
|---|---|
| Melting Point | 110-115°C |
| Melting Point | 110-115 °C |
| Melting Point | 112.5 °C |
| Solubility | 101 |
| LogP | 2.8 |
| LogP | log Kow = 1.70 |
cetirizine; 83881-51-0; Cetirizina; Virlix; Ziptek; Cetryn; Setir; Cetirizinum; Cetirizin; Hitrizin Film Tablet; Cetiderm; Reactine; 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid; 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid; 2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid; YO7261ME24
| Reported hazard statements | H302 (100%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Cetirizine · CAS 83881-51-0 · C21H25ClN2O3. UNII YO7261ME24. Boiling Point: 542.1; Melting Point: 110-115°C; Melting Point: 110-115 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 西替利嗪