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西立伐他汀

CAS 145599-86-6C26H34FNO5MW 459.5

西立伐他汀(CAS 145599-86-6)属医药中间体及原料药类产品,分子式 C26H34FNO5,分子量 459.5。济南圣和化工有限公司常年现货供应该产品,常规纯度 按批次COA提供(不公开发布),可按客户需求安排分装包装,欢迎邮件或来电询价。

产品概览

CAS号145599-86-6
分子式C26H34FNO5
分子量459.5
LogP3.4
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域医药中间体及原料药
类别医药中间体及原料药

应用领域

医药中间体及原料药

该产品的下游应用集中在医药中间体及原料药。不同客户工艺差异较大,我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

采购提示:本产品按按订单/批次确认(不公开发布)起订发货,收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存;如需 MSDS 或运输说明,可在询价时一并索取。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择 济南圣和化工有限公司 的理由:产品信息透明(含 CAS、分子式、理化参数)、报价响应快(一个工作日内)、单证齐全(COA/MSS/质检资料按需提供)、支持批量与长期协议供货。如需 西立伐他汀 以外的配套原料,也欢迎一并列出需求清单。

常见问题

西立伐他汀 的 CAS 号是多少?

西立伐他汀 的 CAS 号为 145599-86-6。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

西立伐他汀 有什么用途?

主要应用于医药中间体及原料药。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

CERIVASTATIN · CAS 145599-86-6 · C26H34FNO5. UNII AM91H2KS67. LogP: 3.4; LogP: 3.26.

Identification

CAS Registry Number145599-86-6
PubChem CID446156
Molecular formulaC26H34FNO5
IUPAC name(E,3R,5S)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)-3-pyridinyl]-3,5-dihydroxyhept-6-enoic acid
UNII (FDA)AM91H2KS67

Computed Descriptors

Molecular Weight459.5
XLogP33.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count11
Exact Mass459.24210135
Monoisotopic Mass459.24210135
Topological Polar Surface Area99.9
Heavy Atom Count33
Formal Charge0

Physical & Chemical Properties

LogP3.4
LogP3.26

Physical description & handling notes

  • Highly solubility
  • pKa1 = 3.9 (carboxylic acid); pKa2 = 5.4 (pyridine)
  • 217.7 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID0046488]
  • 216.3 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID0046488]
  • 217.7 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID0046488]
  • Mol wt 481.53. Solid, specific optical rotation at 20 °C for D (sodium) line = +24.1 deg (c = 1 in ethanol) /Sodium salt/

Documented Uses

  • ... Most effective and best-tolerated agents for treating dyslipidemia. /Statins/
  • ... agent that promotes a reduction of lipoprotein levels in the blood.
  • Hydroxymethyglutaryl-CoA Reductase Inhibitors
  • Prepared and claimed as methyl ester: R. Angerbauer et al., European patent office 325130; eidem, US patent 5006530; as (+)-form sodium salt: eidem, US patent (1989, 1991, 1993 all to Bayer).
  • Used as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
  • MEDICATION: Antihyperlipoproteinemic

Synonyms

cerivastatin; 145599-86-6; Lipobay; Cerivastatina; AM91H2KS67; CHEBI:3558; (3R,5S,6E)-7-(4-(p-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoic acid; DTXSID9022786; cerivastatinum; RefChem:575215; DTXCID402786; C10AA06; cerivastatin acid; (3R,5S,E)-7-(4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl)-3,5-dihydroxyhept-6-enoic acid; Cerivastatin (INN); CERIVASTATIN [INN]

Frequently Asked Questions

What are the CAS number and molecular formula of CERIVASTATIN?

CAS 145599-86-6; molecular formula C26H34FNO5; molecular weight — g/mol.

What other names is CERIVASTATIN known by?

cerivastatin, 145599-86-6, Lipobay, Cerivastatina, AM91H2KS67, CHEBI:3558.

What are the key physical properties of CERIVASTATIN?

LogP: 3.4; LogP: 3.26.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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English page: CERIVASTATIN

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