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Ceritinib

CAS 1032900-25-6C28H36ClN5O3SMW 558.1

Ceritinib (CAS No. 1032900-25-6) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of per batch COA (not published). Main applications include Pharmaceutical Intermediates &APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number1032900-25-6
Molecular FormulaC28H36ClN5O3S
Molecular Weight558.1
LogP6.4
Purityper batch COA (not published)
Packagingper order / batch confirmation (not published)
ApplicationsPharmaceutical Intermediates &APIs
CategoryPharmaceutical Intermediates & APIs

Applications

Pharmaceutical Intermediates &APIs

Packaging & Storage

Packagingper order / batch confirmation (not published)
Purityper batch COA (not published)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Product Profile

Product Overview

Ceritinib is a pharmaceutical intermediate or API compound with CAS registry number 1032900-25-6 and molecular formula C28H36ClN5O3S (molecular weight 558.1), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Pharmaceutical intermediates and APIs are critical building blocks for drug synthesis, with strict requirements on purity, impurities and process consistency.

Ceritinib is typically applied in Pharmaceutical Intermediates &amp, APIs.

Jinan Shenghe Chemical Co., Ltd. supplies Ceritinib with stable inventory and provides a Certificate of Analysis (COA) with each batch; custom repacking is available per process requirement.

Chemical Identity & Nomenclature

CAS number: 1032900-25-6 — searchable in PubChem for physicochemical, safety and regulatory data.

Its molecular formula C28H36ClN5O3S comprises 28 C, 36 H, 1 Cl, 5 N, 3 O, 1 S atoms.

Also known as: Ceritinib

Category: pharmaceutical intermediates and APIs

Applications & Use Cases

Used in API synthesis, formulation and pre-clinical research; supplied with COA and impurity-profile documentation.

In the Pharmaceutical Intermediates &amp field, Ceritinib is selected for its consistent quality and documented specifications. In the APIs field, Ceritinib is selected for its consistent quality and documented specifications.

Specifications & Quality

Typical purity is per batch COA (not published). Packaging is per order / batch confirmation (not published). Storage: sealed, in a cool and dry place. Each batch ships with a COA; MSDS and other technical documents are available on request.

Sourcing & Support

Supplier: Jinan Shenghe Chemical Co., Ltd.. Samples can be arranged on request; lead time depends on stock and order size. Quotes are returned within one business day by email or WhatsApp.

Email: info@591daili.com · Tel/WhatsApp: +86-18553102138

Frequently Asked Questions

What is the CAS number of Ceritinib?

The CAS number of Ceritinib is 1032900-25-6.

What purity and packaging are available?

Typical purity is per batch COA (not published), supplied in per order / batch confirmation (not published), with COA provided.

What are the applications of Ceritinib?

Main applications include Pharmaceutical Intermediates &APIs.

What quality documents are provided?

Each batch ships with a Certificate of Analysis (COA). MSDS and other technical documents are available on request.

How should Ceritinib be stored and handled?

Store sealed in a cool, dry place. Handling and PPE follow the MSDS supplied with the batch; general chemical-handling precautions are recommended.

Can I request a sample?

Samples are available on request. Please contact us at info@591daili.com or via WhatsApp for details.

How do I buy Ceritinib or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Ceritinib · CAS 1032900-25-6 · C28H36ClN5O3S. UNII K418KG2GET.

Identification

CAS Registry Number1032900-25-6
PubChem CID57379345
Molecular formulaC28H36ClN5O3S
IUPAC name5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine
UNII (FDA)K418KG2GET

Computed Descriptors

Molecular Weight558.1
XLogP36.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Exact Mass557.2227389
Monoisotopic Mass557.2227389
Topological Polar Surface Area114
Heavy Atom Count38
Formal Charge0

Physical description & handling notes

  • 9.7 and 4.1

GHS Hazard Classification

Reported hazard statementsH302 (33.3%), H360 (16.7%), H372 (66.7%), H400 (16.7%), H410 (66.7%)

H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]

H360 (16.7%): May damage fertility or the unborn child [Danger Reproductive toxicity]

Documented Uses

  • Ceritinib is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). Ceritinib is associated with a moderate rate of serum aminotransferase elevations during therapy and rare instances of clinically apparent acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Tyrosine Kinase Inhibitors
  • Ceritinib is approved to treat:
  • • Non-small cell lung cancer that is ALK positive and has metastasized (spread to other parts of the body). It is used in adults.
  • Ceritinib is also being studied in the treatment of other types of cancer.
  • Avoid grapefruit products. Grapefruit inhibits the CYP3A metabolism of ceritinib, which may increase its serum concentration.

Synonyms

ceritinib; 1032900-25-6; LDK378; ZYKADIA; LDK-378; NVP-LDK378-NX; LDK 378; K418KG2GET; ceritinibum; NVP-LDK-378-NX; CHEBI:78432; DTXSID10725373; RefChem:57924; DTXCID50676118; L01XE28; 811-457-8

Frequently Asked Questions

What are the CAS number and molecular formula of Ceritinib?

CAS 1032900-25-6; molecular formula C28H36ClN5O3S; molecular weight — g/mol.

What other names is Ceritinib known by?

ceritinib, 1032900-25-6, LDK378, ZYKADIA, LDK-378, NVP-LDK378-NX.

Is Ceritinib classified as hazardous?

Hazard statements reported: H302, H360, H372, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

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