卡莫司汀（CAS 154-93-8）：分子式 C5H9Cl2N3O2、分子量 214.05。
| CAS号 | 154-93-8 |
|---|---|
| 分子式 | C5H9Cl2N3O2 |
| 分子量 | 214.05 |
| 熔点 | 86 to 90 °F (NTP, 1992) |
| LogP | 1.53 |
| 应用领域 | Uses: Medication to treat cancer of the lymph system、cancerous brain tumors、and a certain type of bone marrow cancer、THERAPEUTIC CATEGORY: Antineoplastic、For the treatment of brain tumors、multiple myeloma、Hodgkin's disease and Non-Hodgkin's lymphomas.、Methods of Manufacturing:、Carmustine、may be synthesized by nitrosation with sodium nitrite of the appropriate substituted uera - in this case 1、3-bis(2-chloroethyl)urea - in a cold、acid medium (e.g.、formic acid).、Formulations、Preparations: Carmubris、Carmustin、Nitrumon、Local: Implants: 7.7 mg (of carmustine per wafer) Gliadel Wafer (MGI Pharma).、Parenteral: For injection、for IV infusion: 100 mg BiCNU (Bristol-Myers Squibb).、General Manufacturing Information: An antineoplastic nitrosourea、... designed to deliver carmustine directly into the surgical cavity created when a brain tumor is resected、Gliadel wafer |
登记用途：Uses: Medication to treat cancer of the lymph system、cancerous brain tumors、and a certain type of bone marrow cancer、THERAPEUTIC CATEGORY: Antineoplastic、For the treatment of brain tumors、multiple myeloma、Hodgkin's disease and Non-Hodgkin's lymphomas.、Methods of Manufacturing:、Carmustine、may be synthesized by nitrosation with sodium nitrite of the appropriate substituted uera - in this case 1、3-bis(2-chloroethyl)urea - in a cold、acid medium (e.g.、formic acid).、Formulations、Preparations: Carmubris、Carmustin、Nitrumon、Local: Implants: 7.7 mg (of carmustine per wafer) Gliadel Wafer (MGI Pharma).、Parenteral: For injection、for IV infusion: 100 mg BiCNU (Bristol-Myers Squibb).、General Manufacturing Information: An antineoplastic nitrosourea、... designed to deliver carmustine directly into the surgical cavity created when a brain tumor is resected、Gliadel wafer。
卡莫司汀 是一种化工化合物，登记 CAS 号为 154-93-8，分子式 C5H9Cl2N3O2（分子量 214.05）。
登记 CAS 号：154-93-8
其分子式 C5H9Cl2N3O2 由 5 个碳、9 个氢、2 个氯、3 个氮、2 个氧 组成。
别名/同义词：卡莫司汀 · carmustine
卡莫司汀 的 CAS 登记号为 154-93-8。
分子式 C5H9Cl2N3O2，分子量 214.05。
别名/同义词：卡莫司汀、carmustine。
登记用途：Uses: Medication to treat cancer of the lymph system、cancerous brain tumors、and a certain type of bone marrow cancer、THERAPEUTIC CATEGORY: Antineoplastic、For the treatment of brain tumors、multiple myeloma、Hodgkin's disease and Non-Hodgkin's lymphomas.、Methods of Manufacturing:、Carmustine、may be synthesized by nitrosation with sodium nitrite of the appropriate substituted uera - in this case 1、3-bis(2-chloroethyl)urea - in a cold、acid medium (e.g.、formic acid).、Formulations、Preparations: Carmubris、Carmustin、Nitrumon、Local: Implants: 7.7 mg (of carmustine per wafer) Gliadel Wafer (MGI Pharma).、Parenteral: For injection、for IV infusion: 100 mg BiCNU (Bristol-Myers Squibb).、General Manufacturing Information: An antineoplastic nitrosourea、... designed to deliver carmustine directly into the surgical cavity created when a brain tumor is resected、Gliadel wafer。
卡莫司汀（CAS 154-93-8）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 154-93-8 |
|---|---|
| PubChem CID | 2578 |
| Molecular formula | C5H9Cl2N3O2 |
| IUPAC name | 1,3-bis(2-chloroethyl)-1-nitrosourea |
| UNII (FDA) | U68WG3173Y |
| Molecular Weight | 214.05 |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 213.0071819 |
| Monoisotopic Mass | 213.0071819 |
| Topological Polar Surface Area | 61.8 |
| Heavy Atom Count | 12 |
| Melting Point | 86 to 90 °F (NTP, 1992) |
|---|---|
| Melting Point | 31 |
| Melting Point | 31 °C |
| Solubility | 4000 |
| Solubility | In water, 4.0X10+3 mg/L at 25 °C |
| Solubility | 1.53e+00 g/L |
| LogP | 1.53 |
| LogP | log kow = 1.53 |
| LogP | 1.5 |
carmustine; 154-93-8; 1,3-Bis(2-chloroethyl)-1-nitrosourea; BCNU; Carmustin; Nitrumon; Carmubris; BiCNU; Becenun; Bischloroethyl nitrosourea; Carmustina; Carmustinum; Bischlorethylnitrosurea; N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA; Bischlorethylnitrosourea; Becenum
| Reported hazard statements | H300 (100%), H350 (97.6%), H360 (97.6%), H341, H370, H372 |
|---|
H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]
H350 (97.6%): May cause cancer [Danger Carcinogenicity]
carmustine · CAS 154-93-8 · C5H9Cl2N3O2. UNII U68WG3173Y. Melting Point: 86 to 90 °F (NTP, 1992); Melting Point: 31; Melting Point: 31 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: carmustine