Calcium Gluconate (CAS 299-28-5) — formula C12H22CaO14, molecular weight 430.06 g/mol.
| CAS Number | 299-28-5 |
|---|---|
| Molecular Formula | C12H22CaO14 |
| Molecular Weight | 430.06 g/mol |
| Melting Point | 120 °C |
| Applications | Uses: CIR ingredient: Calcium Gluconate, Used in sewage purification, coffee processing (anti-caking agent), and food and drugs (sequestering, buffering, and gelling agent), Also has veterinary use for hypocalcemic conditions, [HSDB] Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, Also used as a calcium supplement in injection solutions, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Sewer and Wastewater Treatment [Category: Industry], Cement Producing [Category: Industry], In sewage purification, in coffee powders to prevent caking, A sequestering agent, food additive, as buffer, in vitamin tablets, Gelling agent in foods, sequestrant in foods, misc uses as a food additive, THERAP CAT (vet): In hypocalcemic states, including bovine milk fever, For more Uses (Complete) data for CALCIUM GLUCONATE (7 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACIDITY_REGULATOR, FIRMING_AGENT, NUTRIENT_SUPPLEMENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Oral care, Humectant, Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:, • Personal Care, Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate., D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds, eg, Aspergillus niger, or by bromine., Formulations, Preparations: Calcium gluconate, USP ... contains 9% calcium ... Available as calcium gluconate tablets, USP, containing 325, 500, 650, or 1000 mg of the salt ... for im and iv injection, calcium gluconate injection, admin as 10% soln (0.45 mEq Ca++, mL)., Grades: technical, FCC, special for ampules., Due to its limited solubility, calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent., Calcium gluconate injection:a 10% soln, 9.3 mg of Ca+2, mL ... 10-mL vial, U.S. Production: (1971) 2.97X10+8 grams (sales), (1975) Probably greater than 4.54X10+5 grams, U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds), (1975) 3.24X10+6 g (Gluconic acid compounds), U.S. Exports: (1972) No Data, (1975) No Data, General Manufacturing Information: D-Gluconic acid, calcium salt (2:1): ACTIVE, More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. .., ca d-saccharate is used in, prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495, 675 and German 702, 185., Incompatibilities - sol calcium salts are pptd by borates, carbonates, citrates, oxalates, sulfates, and tartrates., Calcium chloride, Incompatibilities of iv additives: cephalothin sodium, magnesium sulfate, novobiocin (albamycin) sodium, prochlorperazine (compazine) edisylate, sodium bicarbonate (dependent on concn of sodium bicarbonate, and calcium). |
Documented applications: Uses: CIR ingredient: Calcium Gluconate, Used in sewage purification, coffee processing (anti-caking agent), and food and drugs (sequestering, buffering, and gelling agent), Also has veterinary use for hypocalcemic conditions, [HSDB] Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, Also used as a calcium supplement in injection solutions, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Sewer and Wastewater Treatment [Category: Industry], Cement Producing [Category: Industry], In sewage purification, in coffee powders to prevent caking, A sequestering agent, food additive, as buffer, in vitamin tablets, Gelling agent in foods, sequestrant in foods, misc uses as a food additive, THERAP CAT (vet): In hypocalcemic states, including bovine milk fever, For more Uses (Complete) data for CALCIUM GLUCONATE (7 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACIDITY_REGULATOR, FIRMING_AGENT, NUTRIENT_SUPPLEMENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Oral care, Humectant, Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:, • Personal Care, Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate., D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds, eg, Aspergillus niger, or by bromine., Formulations, Preparations: Calcium gluconate, USP ... contains 9% calcium ... Available as calcium gluconate tablets, USP, containing 325, 500, 650, or 1000 mg of the salt ... for im and iv injection, calcium gluconate injection, admin as 10% soln (0.45 mEq Ca++, mL)., Grades: technical, FCC, special for ampules., Due to its limited solubility, calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent., Calcium gluconate injection:a 10% soln, 9.3 mg of Ca+2, mL ... 10-mL vial, U.S. Production: (1971) 2.97X10+8 grams (sales), (1975) Probably greater than 4.54X10+5 grams, U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds), (1975) 3.24X10+6 g (Gluconic acid compounds), U.S. Exports: (1972) No Data, (1975) No Data, General Manufacturing Information: D-Gluconic acid, calcium salt (2:1): ACTIVE, More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. .., ca d-saccharate is used in, prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495, 675 and German 702, 185., Incompatibilities - sol calcium salts are pptd by borates, carbonates, citrates, oxalates, sulfates, and tartrates., Calcium chloride, Incompatibilities of iv additives: cephalothin sodium, magnesium sulfate, novobiocin (albamycin) sodium, prochlorperazine (compazine) edisylate, sodium bicarbonate (dependent on concn of sodium bicarbonate, and calcium)..
Calcium Gluconate is a chemical compound with CAS registry number 299-28-5 and molecular formula C12H22CaO14 (molecular weight 430.06 g/mol).
CAS number: 299-28-5
Its molecular formula C12H22CaO14 comprises 12 C, 22 H, 1 Ca, 14 O atoms.
Also known as: Calcium Gluconate · 葡萄糖酸钙
The CAS registry number of Calcium Gluconate is 299-28-5.
Molecular formula C12H22CaO14, molecular weight 430.06 g/mol.
It is also registered under: Calcium Gluconate, 葡萄糖酸钙.
Recorded applications: Uses: CIR ingredient: Calcium Gluconate, Used in sewage purification, coffee processing (anti-caking agent), and food and drugs (sequestering, buffering, and gelling agent), Also has veterinary use for hypocalcemic conditions, [HSDB] Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, Also used as a calcium supplement in injection solutions, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Sewer and Wastewater Treatment [Category: Industry], Cement Producing [Category: Industry], In sewage purification, in coffee powders to prevent caking, A sequestering agent, food additive, as buffer, in vitamin tablets, Gelling agent in foods, sequestrant in foods, misc uses as a food additive, THERAP CAT (vet): In hypocalcemic states, including bovine milk fever, For more Uses (Complete) data for CALCIUM GLUCONATE (7 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Skin Conditioning Agents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACIDITY_REGULATOR, FIRMING_AGENT, NUTRIENT_SUPPLEMENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Oral care, Humectant, Household Products: Information on 6 consumer products that contain Calcium Gluconate in the following categories is provided:, • Personal Care, Methods of Manufacturing: Neutralization of gluconic acid with lime or calcium carbonate., D-Glucose is oxidized to gluconic acid in the presence of calcium carbonate. The oxidation may be effected by certain molds, eg, Aspergillus niger, or by bromine., Formulations, Preparations: Calcium gluconate, USP ... contains 9% calcium ... Available as calcium gluconate tablets, USP, containing 325, 500, 650, or 1000 mg of the salt ... for im and iv injection, calcium gluconate injection, admin as 10% soln (0.45 mEq Ca++, mL)., Grades: technical, FCC, special for ampules., Due to its limited solubility, calcium gluconate must frequently be suspended in liquid mixtures and tragacanth is useful as a suspending agent., Calcium gluconate injection:a 10% soln, 9.3 mg of Ca+2, mL ... 10-mL vial, U.S. Production: (1971) 2.97X10+8 grams (sales), (1975) Probably greater than 4.54X10+5 grams, U.S. Imports: (1972) 8.13X10+8 grams (Gluconic acid compounds), (1975) 3.24X10+6 g (Gluconic acid compounds), U.S. Exports: (1972) No Data, (1975) No Data, General Manufacturing Information: D-Gluconic acid, calcium salt (2:1): ACTIVE, More concn (20 to 30%) aq soln...obtained by addn of boric acid or similar complex-forming acids. .., ca d-saccharate is used in, prepn of supersaturated injectable soln of calcium gluconate... injectable soln of calcium gluconate containing sodium ascorbate...described...British patent 495, 675 and German 702, 185., Incompatibilities - sol calcium salts are pptd by borates, carbonates, citrates, oxalates, sulfates, and tartrates., Calcium chloride, Incompatibilities of iv additives: cephalothin sodium, magnesium sulfate, novobiocin (albamycin) sodium, prochlorperazine (compazine) edisylate, sodium bicarbonate (dependent on concn of sodium bicarbonate, and calcium)..
Independent reference data for Calcium Gluconate (CAS 299-28-5), compiled from public chemistry databases.
| CAS 号 | 299-28-5 |
|---|---|
| PubChem CID | 9290 |
| 分子式 | C12H22CaO14 |
| 分子量 | 430.06 g/mol |
| IUPAC 名称 | calcium bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) |
| InChIKey | NEEHYRZPVYRGPP-IYEMJOQQSA-L |
| UNII（FDA） | SQE6VB453K |
| ChEBI 编号 | CHEBI:3309 |
| ATC 编码（WHO） | A12AA03 |
| Molecular Weight | 430.37 |
|---|---|
| Hydrogen Bond Donor Count | 10 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 8 |
| Exact Mass | 430.0635462 |
| Monoisotopic Mass | 430.0635462 |
| Topological Polar Surface Area | 283 |
| Heavy Atom Count | 27 |
| Melting Point | 120 °C |
|---|---|
| Melting Point | 178 °C |
| Solubility | Sol in water 3.3 g/100 cc at 15 °C |
| Solubility | In water, 3.33X10+4 mg/L at 25 °C |
| Density | 0.30-0.65 g/cm³ |
CALCIUM GLUCONATE; 299-28-5; Calcium D-gluconate; D-Gluconic acid, calcium salt (2:1); Calcicol; Calglucon; Calciofon; Calcipur; Calglucol; Dragocal; Glucobiogen; Ebucin; Kalpren; Novocal; Calcarea gluconica; Calcium di-gluconate
| 法规与食品接触 | FDA Substance added to food: FIRMING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULATION AID, NU ACIDITY_REGULATOR; FIRMING_AGENT; NUTRIENT_SUPPLEMENT; SEQUE: Food Additives FIRMING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULATION AID, NUTRIENT SUPPLEMENT, SEQUESTRANT 在一般食品中用作钙源 Scientific procedures FDA has no questions |
|---|---|
| GHS 通报统计 | 98.6% (68 / 69) |
| GHS 通报统计 | 98.6% (68 / 69) |
|---|
葡萄糖酸钙 的 CAS 号为 299-28-5，分子式 C12H22CaO14，分子量 430.06 g/mol。 UNII SQE6VB453K; ChEBI 3309; InChIKey NEEHYRZPVYRGPP-IYEMJOQQSA-L. Melting Point: 120 °C; Melting Point: 178 °C; Solubility: Sol in water 3.3 g/100 cc at 15 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 葡萄糖酸钙