乙二胺四乙酸二钠钙二水合物（CAS 23411-34-9）：分子式 C10H12CaN2O8.2Na、分子量 374.27。
| CAS号 | 23411-34-9 |
|---|---|
| 分子式 | C10H12CaN2O8.2Na |
| 分子量 | 374.27 |
| 熔点 | >300 |
| 应用领域 | Uses: CIR ingredient: Calcium Disodium EDTA、Used as an antidote in metal poisoning、a sequestering agent in foods、an in vitro anticoagulant of blood、and an antigushing agent in beer、Also used in drugs、cosmetics、and other chemicals to sequester trace minerals and prevent oxidation and discoloration、[HSDB]、MEDICATION、Used in pharmaceutical formulations as a chelating agent in concentrations between 0.01-0.1% w、v. Usually edentate calcium disodium is used in pharmaceutical formulations in preference to edentate or sodium edentate to prevent calcium depletion occurring in the body.、Calcium Disodium EDTA is a preservative、sequestrant、flavoring agent、and color retention agent.、... Antigushing agent in fermented malt beverages.、Use Classification: Food additives、Fragrance Ingredients、Food Additives -> PRESERVATIVE、SEQUESTRANT -> JECFA Functional Classes、Cosmetics -> Chelating、Industry Uses: Chelating agent、Soil amendments (fertilizers)、CBI、Consumer Uses: Soil amendments (fertilizers)、Household Products: Information on 14 consumer products that contain Calcium Disodium Edta in the following categories is provided:、• Commercial、Institutional、• Inside the Home、Methods of Manufacturing: ... By boiling an aqueous solution of edetate disodium with slightly more than an equimolar quantity of calcium carbonate until carbon dioxide no longer is evolved、filtering while hot、and crystallizing.、Formulations、Preparations: Calcium Disodium Versenate injection、5 mL ampul containing 200 mg of edetate calcium disodium per mL (1 g per ampul)、in boxes containing 6 ampuls.、The food- and pharmaceutical-grade chemical is a mixture of the dihydrate and trihydrate of Calcium Disodium EDTA (predominantly the dihydrate)、and contains not less than 97.0% and not more than 100.2% of C10H12CaN2Na2O8、calculated on the anhydrous basis.、Grades: USP、FCC、U.S. Production: 2023: 700、000 - <850、000 lb、2022: 1、000、000 - <2、500、2021: 1、2020: 1、Agriculture、Forestry、Fishing and Hunting、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Calciate(2-)、[[N、N'-1、2-ethanediylbis[N-[(carboxy-.kappa.O)methyl]glycinato-.kappa.N、.kappa.O]](4-)]-、sodium (1:2)、(OC-6-21)-: ACTIVE、Ethylenediaminetetraacetic acid (edta)、its sodium salt (... Na2edta)、and closely related compounds chelate many divalent and trivalent metals.、... Edetate calcium disodium (CaNa2edta) can be used for treatment of poisoning by metals that have higher affinity for the chelating agent than does Ca2+.、The calcium disodium salt is a mixture of di- and trihydrate disodium calcium EDTA.、Sequestering agents: 1 g complexes 215 mg CaCO3. Usually added to pharmaceuticals in form of calcium disodium salt to prevent calcium-depleting action in the body. |
登记用途：Uses: CIR ingredient: Calcium Disodium EDTA、Used as an antidote in metal poisoning、a sequestering agent in foods、an in vitro anticoagulant of blood、and an antigushing agent in beer、Also used in drugs、cosmetics、and other chemicals to sequester trace minerals and prevent oxidation and discoloration、[HSDB]、MEDICATION、Used in pharmaceutical formulations as a chelating agent in concentrations between 0.01-0.1% w、v. Usually edentate calcium disodium is used in pharmaceutical formulations in preference to edentate or sodium edentate to prevent calcium depletion occurring in the body.、Calcium Disodium EDTA is a preservative、sequestrant、flavoring agent、and color retention agent.、... Antigushing agent in fermented malt beverages.、Use Classification: Food additives、Fragrance Ingredients、Food Additives -> PRESERVATIVE、SEQUESTRANT -> JECFA Functional Classes、Cosmetics -> Chelating、Industry Uses: Chelating agent、Soil amendments (fertilizers)、CBI、Consumer Uses: Soil amendments (fertilizers)、Household Products: Information on 14 consumer products that contain Calcium Disodium Edta in the following categories is provided:、• Commercial、Institutional、• Inside the Home、Methods of Manufacturing: ... By boiling an aqueous solution of edetate disodium with slightly more than an equimolar quantity of calcium carbonate until carbon dioxide no longer is evolved、filtering while hot、and crystallizing.、Formulations、Preparations: Calcium Disodium Versenate injection、5 mL ampul containing 200 mg of edetate calcium disodium per mL (1 g per ampul)、in boxes containing 6 ampuls.、The food- and pharmaceutical-grade chemical is a mixture of the dihydrate and trihydrate of Calcium Disodium EDTA (predominantly the dihydrate)、and contains not less than 97.0% and not more than 100.2% of C10H12CaN2Na2O8、calculated on the anhydrous basis.、Grades: USP、FCC、U.S. Production: 2023: 700、000 - <850、000 lb、2022: 1、000、000 - <2、500、2021: 1、2020: 1、Agriculture、Forestry、Fishing and Hunting、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Calciate(2-)、[[N、N'-1、2-ethanediylbis[N-[(carboxy-.kappa.O)methyl]glycinato-.kappa.N、.kappa.O]](4-)]-、sodium (1:2)、(OC-6-21)-: ACTIVE、Ethylenediaminetetraacetic acid (edta)、its sodium salt (... Na2edta)、and closely related compounds chelate many divalent and trivalent metals.、... Edetate calcium disodium (CaNa2edta) can be used for treatment of poisoning by metals that have higher affinity for the chelating agent than does Ca2+.、The calcium disodium salt is a mixture of di- and trihydrate disodium calcium EDTA.、Sequestering agents: 1 g complexes 215 mg CaCO3. Usually added to pharmaceuticals in form of calcium disodium salt to prevent calcium-depleting action in the body.。
乙二胺四乙酸二钠钙二水合物 是一种化工化合物，登记 CAS 号为 23411-34-9，分子式 C10H12CaN2O8.2Na（分子量 374.27）。
登记 CAS 号：23411-34-9
其分子式 C10H12CaN2O8.2Na 由 10 个碳、12 个氢、1 个钙、2 个氮、8 个氧、1 个钠 组成。
别名/同义词：乙二胺四乙酸二钠钙二水合物 · Calcium disodium edetate dihydrate
乙二胺四乙酸二钠钙二水合物 的 CAS 登记号为 23411-34-9。
分子式 C10H12CaN2O8.2Na，分子量 374.27。
别名/同义词：乙二胺四乙酸二钠钙二水合物、Calcium disodium edetate dihydrate。
登记用途：Uses: CIR ingredient: Calcium Disodium EDTA、Used as an antidote in metal poisoning、a sequestering agent in foods、an in vitro anticoagulant of blood、and an antigushing agent in beer、Also used in drugs、cosmetics、and other chemicals to sequester trace minerals and prevent oxidation and discoloration、[HSDB]、MEDICATION、Used in pharmaceutical formulations as a chelating agent in concentrations between 0.01-0.1% w、v. Usually edentate calcium disodium is used in pharmaceutical formulations in preference to edentate or sodium edentate to prevent calcium depletion occurring in the body.、Calcium Disodium EDTA is a preservative、sequestrant、flavoring agent、and color retention agent.、... Antigushing agent in fermented malt beverages.、Use Classification: Food additives、Fragrance Ingredients、Food Additives -> PRESERVATIVE、SEQUESTRANT -> JECFA Functional Classes、Cosmetics -> Chelating、Industry Uses: Chelating agent、Soil amendments (fertilizers)、CBI、Consumer Uses: Soil amendments (fertilizers)、Household Products: Information on 14 consumer products that contain Calcium Disodium Edta in the following categories is provided:、• Commercial、Institutional、• Inside the Home、Methods of Manufacturing: ... By boiling an aqueous solution of edetate disodium with slightly more than an equimolar quantity of calcium carbonate until carbon dioxide no longer is evolved、filtering while hot、and crystallizing.、Formulations、Preparations: Calcium Disodium Versenate injection、5 mL ampul containing 200 mg of edetate calcium disodium per mL (1 g per ampul)、in boxes containing 6 ampuls.、The food- and pharmaceutical-grade chemical is a mixture of the dihydrate and trihydrate of Calcium Disodium EDTA (predominantly the dihydrate)、and contains not less than 97.0% and not more than 100.2% of C10H12CaN2Na2O8、calculated on the anhydrous basis.、Grades: USP、FCC、U.S. Production: 2023: 700、000 - <850、000 lb、2022: 1、000、000 - <2、500、2021: 1、2020: 1、Agriculture、Forestry、Fishing and Hunting、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Calciate(2-)、[[N、N'-1、2-ethanediylbis[N-[(carboxy-.kappa.O)methyl]glycinato-.kappa.N、.kappa.O]](4-)]-、sodium (1:2)、(OC-6-21)-: ACTIVE、Ethylenediaminetetraacetic acid (edta)、its sodium salt (... Na2edta)、and closely related compounds chelate many divalent and trivalent metals.、... Edetate calcium disodium (CaNa2edta) can be used for treatment of poisoning by metals that have higher affinity for the chelating agent than does Ca2+.、The calcium disodium salt is a mixture of di- and trihydrate disodium calcium EDTA.、Sequestering agents: 1 g complexes 215 mg CaCO3. Usually added to pharmaceuticals in form of calcium disodium salt to prevent calcium-depleting action in the body.。
乙二胺四乙酸二钠钙二水合物（CAS 23411-34-9）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 23411-34-9 |
|---|---|
| PubChem CID | 6093170 |
| Molecular formula | C10H12CaN2O8.2Na |
| IUPAC name | calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate |
| UNII (FDA) | 8U5D034955 |
| Molecular Weight | 374.27 |
|---|---|
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 7 |
| Exact Mass | 374.0014948 |
| Monoisotopic Mass | 374.0014948 |
| Topological Polar Surface Area | 167 |
| Heavy Atom Count | 23 |
| Melting Point | >300 |
|---|---|
| Color Additive Status | 73.1 |
| Color Additive Status | 172.120 |
| Color Additive Status | 172.135 |
| Color Additive Status | 175.105 |
Edetate calcium disodium; EDTA calcium disodium; Detoxamin; Calcium disodium ethylenediaminetetraacetate; Edetate calcium disodium anhydrous; DTXSID2036409; INS NO.385; INS-385; Edetate Calcium Disodium (anhydrous); NSC-310151; C10H12CaN2Na2O8; DTXCID0016409; E-385; 8U5D034955; Calcium disodium edetate hydrate; Calcium disodium EDTA dihydrate
| Regulatory & Food Contact | FDA Regulatory Status of Color Additives: Foods, Drugs FDA Substance added to food: ANTIOXIDANT, COLOR OR COLORING ADJUNCT, FLAVOR ENHANCER, FUMIGANT, SEQUESTRANT FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS PRESERVATIVE; SEQUESTRANT: Food Additives EDTA, CALCIUM DISODIUM Calcium disodium ethylenediaminetetraacetate (EDTA) |
|---|---|
| GHS notification summary | 81.1% (210 / 259) |
| GHS notification summary | 81.1% (210 / 259) |
|---|---|
| Reported hazard statements | H315 (17.4%), H319 (17.4%), H335 (17.4%) |
This chemical does not meet GHS hazard criteria for 81.1% (210 of 259) of all reports.
H315 (17.4%): Causes skin irritation [Warning Skin corrosion/irritation]
Calcium disodium edetate dihydrate · CAS 23411-34-9 · C10H12CaN2O8.2Na. UNII 8U5D034955. Melting Point: >300; Color Additive Status: 73.1; Color Additive Status: 172.120.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Calcium disodium edetate dihydrate