氢溴酸安非他酮

Description

Bupropion Hydrobromide · CAS 905818-69-1 · C13H19BrClNO. UNII E70G3G5863.

Identification

CAS Registry Number	905818-69-1
PubChem CID	11984562
Molecular formula	C13H19BrClNO
IUPAC name	2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydrobromide
UNII (FDA)	E70G3G5863

Computed Descriptors

Molecular Weight	320.65
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	319.03385
Monoisotopic Mass	319.03385
Topological Polar Surface Area	29.1
Heavy Atom Count	17
Formal Charge	0
Complexity	247

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• For the treatment of depression and as aid to smoking cessation.
• Increased Norepinephrine Activity [PE]; Increased Dopamine Activity [PE]; Norepinephrine Uptake Inhibitors [MoA]; Dopamine Uptake Inhibitors [MoA]; Aminoketone [EPC]
• Reduction of the carbonyl groupand/or hydroxylation of the tert-butyl group of bupropion. Route of Elimination: Bupropion is extensively metabolized in humans. Oxidation of the bupropion side chain results in the formation of a glycine conjugate of metachlorobenzoic acid, which is then excreted as the major urinary metabolite. Following oral administration of 200 mg of 14C-bupropion in humans, 87% and 10% of the radioactive dose were recovered in the urine and feces, respectively. However, the fraction of the oral

Synonyms

Bupropion hydrobromide; 905818-69-1; Aplenzin; bupropion HBr; Aplenzin ER; UNII-E70G3G5863; BVF-033; E70G3G5863; BUPROPION HYDROBROMIDE (MART.); BUPROPION HYDROBROMIDE [MART.]; BUPROPION HYDROBROMIDE (USP-RS); BUPROPION HYDROBROMIDE [USP-RS]; (2RS)-1-(3-CHLOROPHENYL)-2-((1,1-DIMETHYLETHYL)AMINO)PROPAN-1-ONE HBR; 1-PROPANONE, 1-(3-CHLOROPHENYL)-2-((1,1-DIMETHYLETHYL)AMINO)-, HBR (1:1); (2RS)-1-(3-CHLOROPHENYL)-2-((1,1-DIMETHYLETHYL)AMINO)PROPAN-1-ONE HYDROBROMIDE; (2RS)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]propan-1-one hydrobromide

Frequently Asked Questions

What are the CAS number and molecular formula of Bupropion Hydrobromide?

CAS 905818-69-1; molecular formula C13H19BrClNO; molecular weight — g/mol.

What other names is Bupropion Hydrobromide known by?

Bupropion hydrobromide, 905818-69-1, Aplenzin, bupropion HBr, Aplenzin ER, UNII-E70G3G5863.

Is Bupropion Hydrobromide classified as hazardous?

Hazard statements reported: H302.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.