Bronopol

Description

Bronopol · CAS 52-51-7 · C3H6BrNO4. UNII 6PU1E16C9W. Boiling Point: 305.1 °F at 760 mmHg (NTP, 1992); Boiling Point: 130; Melting Point: 266 to 271 °F (NTP, 1992).

Identification

CAS Registry Number	52-51-7
PubChem CID	2450
Molecular formula	C3H6BrNO4
IUPAC name	2-bromo-2-nitropropane-1,3-diol
UNII (FDA)	6PU1E16C9W

Computed Descriptors

Molecular Weight	199.99
XLogP3	-0.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	198.94802
Monoisotopic Mass	198.94802
Topological Polar Surface Area	86.3
Heavy Atom Count	9
Formal Charge	0

Physical & Chemical Properties

Boiling Point	305.1 °F at 760 mmHg (NTP, 1992)
Boiling Point	130
Melting Point	266 to 271 °F (NTP, 1992)
Melting Point	123-130
Melting Point	131.5 °C
Melting Point	120-122 °C
Flash Point	167 °C
Solubility	25-25g/100mL at 22°C
Solubility	In water, 2.5X10+5 mg/L at 22 °C
Vapor Pressure	1.2601e-05 mmHg at 68 °F (NTP, 1992)

Physical description & handling notes

• 2-bromo-2-nitropropane-1,3-diol appears as white crystals. Ignite easily and burn readily. May detonate under strong shock. Decomposes when heated, evolving toxic gases. Toxic by skin absorption, inhalation or ingestion.
• Liquid
• ODOURLESS WHITE CRYSTALS.
• White crystalline powder
• Crystals from ethyl acetate-chloroform
• Odorless

Regulatory Status

Regulatory & Food Contact

FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS 2-Bromo-2-nitro-1,3-propanediol (CAS Reg. No. 52-51-7) As a preservative for boiler water additive formulations. For use only as a preservative in boiler water additive formulations. The food-contact substance shall be adde

GHS notification summary

0.1% (1 / 2149)

GHS Hazard Classification

GHS notification summary	0.1% (1 / 2149)
Reported hazard statements	H302, H312, H315, H318, H335, H400, H301 (14.4%), H331 (10%)

Documented Uses

• CIR ingredient: 2-Bromo-2-Nitropropane-1,3-Diol
• Bronopol is a preservative and antiseptic used in cosmetics and topical medications. It is used as a preservative in paints, textiles, cooling towers, humidifiers, and hide processing. [Marks, p. 136-7] Used in cleaning agents, paints, cosmetics, glues, paper mills, water systems, metalworking fluids, polishes, and printing inks; [Kanerva, p. 405]
• Metal Machining [Category: Heat or Machine]
• Pulp and Paper Processing [Category: Industry]
• Painting (Pigments, Binders, and Biocides) [Category: Paint]
• Working with Glues and Adhesives [Category: Other]

Synonyms

bronopol; 52-51-7; 2-Bromo-2-nitro-1,3-propanediol; 2-Bromo-2-nitropropane-1,3-diol; Bronosol; Bronocot; Bronotak; Bronidiol; Bronopolu; Lexgard bronopol; Onyxide 500; Bronopolum; 1,3-Propanediol, 2-bromo-2-nitro-; 2-Nitro-2-bromo-1,3-propanediol; DTXSID8024652; beta-Bromo-beta-nitrotrimethyleneglycol

Frequently Asked Questions

What are the CAS number and molecular formula of Bronopol?

CAS 52-51-7; molecular formula C3H6BrNO4; molecular weight — g/mol.

What other names is Bronopol known by?

bronopol, 52-51-7, 2-Bromo-2-nitro-1,3-propanediol, 2-Bromo-2-nitropropane-1,3-diol, Bronosol, Bronocot.

What is the regulatory status of Bronopol?

Documented regulatory listings: FDA Cumulative Estimated Daily Intake (CEDI): FCS; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS.

Is Bronopol classified as hazardous?

0.1% of GHS notifications report no hazard classification (1 of 2149).

What are the key physical properties of Bronopol?

Boiling Point: 305.1 °F at 760 mmHg (NTP, 1992); Boiling Point: 130; Melting Point: 266 to 271 °F (NTP, 1992); Melting Point: 123-130.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.