Berberine

Independent reference data for Berberine (CAS 2086-83-1), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

• Occurs naturally in many plants and used in traditional medicine as an antiprotozoal, antimalarial, antibacterial, and antidiarrheal; [Merck Index]
• Berberine is a quaternary ammonia compound found in many botanical products, including goldenseal, barberry and Oregon grape, which is used for its purported antioxidant and antimicrobial properties for a host of conditions, including obesity, diabetes, hyperlipidemia, heart failure, H. pylori infection and colonic adenoma prevention. Berberine has not been linked to serum aminotransferase elevations during therapy nor to instances of clinically apparent liver injury.

Synonyms and trade names

berberine; 2086-83-1; Umbellatine; Berberin; Berbericine; Majarine; Thalsine; Umbellatin; Berberone; 0I8Y3P32UF; DTXSID9043857; CHEBI:16118; Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-; Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-; 9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium; 9,10-DIMETHOXY-5,6-DIHYDRO(1,3)DIOXOLO(4,5-G)ISOQUINO(3,2-A)ISOQUINOLIN-7-IUM

Regulatory listings held on file

What the public record says

Berberine · CAS 2086-83-1 · C20H18NO4+. UNII 0I8Y3P32UF. Melting Point: 145; Melting Point: 145 °C.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.