BENZOCAINE USP

Description

DEXTRAN SULFATE · CAS 94-09-7 · C9H11NO2. UNII U3RSY48JW5. Boiling Point: 310; Boiling Point: 310 °C; Melting Point: 92.

Identification

CAS Registry Number	94-09-7
PubChem CID	2337
Molecular formula	C9H11NO2
IUPAC name	ethyl 4-aminobenzoate
UNII (FDA)	U3RSY48JW5

Computed Descriptors

Molecular Weight	165.19
XLogP3	1.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	165.078978594
Monoisotopic Mass	165.078978594
Topological Polar Surface Area	52.3
Heavy Atom Count	12
Formal Charge	0

Physical & Chemical Properties

Boiling Point	310
Boiling Point	310 °C
Melting Point	92
Melting Point	92 °C
Solubility	1310
Solubility	In water, 1,310 mg/L at 25 °C
LogP	1.86
LogP	log Kow = 1.86
LogP	1.87
Dissociation Constants	2.51 (at 25 °C)

Physical description & handling notes

• Dry Powder
• Solid
• Rhombohedra from ether
• Needles from water
• One gram dissolves in about 5 ml alcohol, 2 ml chloroform, in about 4 ml ether, and in 30 to 50 ml of expressed almond oil or olive oil. Also sol in dil acids.
• Soluble in acid

Regulatory Status

GHS notification summary	11.1% (39 / 351)

GHS Hazard Classification

GHS notification summary	11.1% (39 / 351)
Reported hazard statements	H317 (77.8%), H370 (47.3%), H411 (11.4%), H402, H412, H372

Documented Uses

• Used as a local anesthetic; [Kanerva, p. 434]
• Use (kg; approx.) in Germany (2009): >1000
• Consumption (g per capita; approx.) in Germany (2009): 0.0122
• Local anesthetic commonly used as a topical pain reliever. Benzocaine is used as a key ingredient in numerous pharmecuticals: Phenazone, an anti-inflammatory; some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as Otitis Media and swimmers ear; some previous diet products such as Ayds; some condoms designed to prevent premature ejaculation. Benzocaine acts to desensitize the penis, and theoretically allows an erection to be maintained. [Wikipedia]
• Information on 23 consumer products that contain Benzocaine in the following categories is provided:
• Benzocaine is produced by reduction of ethyl 4-nitrobenzoate with iron.

Synonyms

benzocaine; Ethyl 4-aminobenzoate; 94-09-7; Ethyl p-aminobenzoate; Anaesthesin; Parathesin; Norcaine; Americaine; Ethyl aminobenzoate; 4-Aminobenzoic acid ethyl ester; Parathesine; Topcaine; Anesthesin; Anesthone; Hurricaine; Norcain

Frequently Asked Questions

What are the CAS number and molecular formula of DEXTRAN SULFATE?

CAS 94-09-7; molecular formula C9H11NO2; molecular weight — g/mol.

What other names is DEXTRAN SULFATE known by?

benzocaine, Ethyl 4-aminobenzoate, 94-09-7, Ethyl p-aminobenzoate, Anaesthesin, Parathesin.

Is DEXTRAN SULFATE classified as hazardous?

11.1% of GHS notifications report no hazard classification (39 of 351).

What are the key physical properties of DEXTRAN SULFATE?

Boiling Point: 310; Boiling Point: 310 °C; Melting Point: 92; Melting Point: 92 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.