苯并巴比妥

Description

benzobarbital · CAS 744-80-9 · C19H16N2O4. UNII YNJ78BD0AH.

Identification

CAS Registry Number	744-80-9
PubChem CID	12938
Molecular formula	C19H16N2O4
IUPAC name	1-benzoyl-5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione
UNII (FDA)	YNJ78BD0AH

Computed Descriptors

Molecular Weight	336.3
XLogP3	3.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	336.11100700
Monoisotopic Mass	336.11100700
Topological Polar Surface Area	83.6
Heavy Atom Count	25
Formal Charge	0

Documented Uses

• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Drugs used to prevent SEIZURES or reduce their severity.
• Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other purposes, e.g. military.

Synonyms

Benzobarbital; 744-80-9; Benzonal; Benzoylluminal; Benzonalum; Benzobarbitalum; 1-Benzoyl-5-ethyl-5-phenylbarbituric acid; DTXSID1046138; YNJ78BD0AH; 5-Ethyl-1-benzoyl-5-phenylbarbituric acid; DTXCID9026138; RefChem:118260; Benzoylphenobarbital; Benzoyluminal; 1-benzoyl-5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione; Benzobarbital [INN]

Frequently Asked Questions

What are the CAS number and molecular formula of benzobarbital?

CAS 744-80-9; molecular formula C19H16N2O4; molecular weight — g/mol.

What other names is benzobarbital known by?

Benzobarbital, 744-80-9, Benzonal, Benzoylluminal, Benzonalum, Benzobarbitalum.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.