苯并[a]芘（CAS 50-32-8）：分子式 C20H12、分子量 252.3。
| CAS号 | 50-32-8 |
|---|---|
| 分子式 | C20H12 |
| 分子量 | 252.3 |
| 熔点 | 349.7 to 351.5 °F (NTP, 1992) |
| 沸点 | 887 °F at 760 mmHg (NTP, 1992) |
| LogP | 6 |
| 应用领域 | Uses: Used as a research chemical、Not commercially used in the US、[HSDB] Formed during incomplete combustion of organic compounds、Highest levels in aluminum production (up to 100 ug、m3)、then roofing and paving (10-20 ug、then lowest exposures: coal liquefaction、coal-tar distillation、wood treatment with creosote、chimney sweeping、and power plants、[Reference #1]、Aluminum Producing [Category: Industry]、Steel Producing [Category: Industry]、Forging [Category: Heat or Machine]、Metal Preparation and Pouring [Category: Foundry]、Petroleum Production and Refining [Category: Industry]、Smelting Copper or Lead [Category: Industry]、Firefighting [Category: Other]、Cleaning Furnaces or Flues [Category: Clean]、Burning Natural Polymers [Category: Burn]、Glass Manufacturing [Category: Industry]、Metal Extraction and Refining [Category: Industry]、Glassblowing [Category: Hobbies]、Smoking cigarettes [Category: Food & Drugs]、Burning biomass fuel for cooking and heating [Category: Environments]、Laboratory chemicals、synthesis of substances.[Sigma-Aldrich、Safety Data Sheet for Benzo、Benzo(a)pyrene、an indirect carcinogen which undergoes metabolism to reactive electrophiles capable of binding covalently to DNA、has been used extensively as a positive control in a variety of short-term tests.、Fuels and related products.、Synthetic Polymer MALDI Matrix Compounds、Substance listed with specific concentration in tattoo ink and、or permanent make up according to EU Commission Regulation 2020、2081. The concentration limit (by weight) is 0.0000005%.、PAHs are released into the environment via the combustion of fossil fuels、coke oven emissions and vehicle exhausts、as well as naturally from forest fires and volcanic eruptions. PAHs from these sources may contaminate nearly water systems. They are also found in coal tar and charbroiled food. (L10)、Use Classification: Food Contaminant -> CONTAMINANT -> JECFA Functional Classes、Industry Uses: Binder、Household Products: Cosmetics product ingredient: Benzo[a]pyrene (BaP) (Benzo[def]chrysene、Benzopyrene)、Reason for Listing:、- Included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907、2006 on the basis of Article 57(d)、Article 57(e)、or Article 57(f) for persistent、bioaccumulative and toxic、or very persistent and very bioaccumulative properties、- Classified by the European Union as a carcinogen、mutagen、and reproductive toxicant Category 1B in Annex VI to Regulation (EC) 1272、2008、- Known to cause cancer and listed under Health and Safety Code section 25249.8 of the California Safe Drinking Water and Toxic Enforcement Act of 1986 (Prop 65)、- Group 1 carcinogen identified by the International Agency for Research on Cancer (IARC). There is sufficient evidence for the carcinogenicity of benzo[a]pyrene in experimental animal studies.、- Identified as priority pollutants in California Water Quality Control Plans under section 303(c) of the federal Clean Water Act and in section 131.38 of title 40 of the Code of Federal Regulations、and identified as pollutants by California or the United States Environmental Protection Agency for one or more water bodies in California under section 303(d) of the federal Clean Water Act and section 130.7 of title 40 of the Code of Federal Regulations、- Identified as Toxic Air Contaminants under sections 93000 and 93001 of title 17 of the California Code of Regulations、- Primary Maximum Contaminant Levels have been established and adopted under section 64431 or section 64444 of chapter 15 of title 22 of the California Code of Regulations、- Identified as “known to be” or “reasonably anticipated to be” a human carcinogen in the 13th Report on Carcinogens、United States Department of Health and Human Services、Public Health Service、National Toxicology Program、- Identified as “carcinogenic to humans”、“likely to be carcinogenic to humans”、or Group B2 carcinogens in the United States Environmental Protection Agency’s Integrated Risk Information System、- The United States Environmental Protection Agency’s Integrated Risk Information System has developed a reference dose or reference concentration based on neurotoxicity、Potential Health Impacts: Bioaccumulation、Carcinogenicity、Environmental Persistence、Genotoxicity、Neurotoxicity、and Reproductive Toxicity、Product count: 1、Information on 3 consumer products that contain Benzo(a)pyrene in the following categories is provided:、• Auto Products、• Inside the Home、Methods of Manufacturing: Synthesis from pyrene and succinic anhydride.、Formulations、Preparations: A reference material of certified high purity is available、U.S. Production: 2023: 1、082、933 lb、2022: 901、772 lb、2021: 1、291、534 lb、2020: 1、051、280 lb、(1978) Not produced commercially in USA、(1982) Not produced commercially in USA、Not produced commercially in the USA.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzo(a)pyrene. National Production Volume: 1、811、363 lb、yr.、SRP: Concern as to validity of data、General Manufacturing Information: Wood Product Manufacturing、Benzo[a]pyrene: ACTIVE、Benzo[a]pyrene occurs naturally in crude oils、shale oils、and coal tars、and is emitted with gases and fly ash from active volcanoes.、There is no commercial production or known use for、benzo(a)pyrene、. Benzo(a)pyrene occurs ubiquitously as a product of incomplete combustion and also occurs in fossil fuels. |
登记用途：Uses: Used as a research chemical、Not commercially used in the US、[HSDB] Formed during incomplete combustion of organic compounds、Highest levels in aluminum production (up to 100 ug、m3)、then roofing and paving (10-20 ug、then lowest exposures: coal liquefaction、coal-tar distillation、wood treatment with creosote、chimney sweeping、and power plants、[Reference #1]、Aluminum Producing [Category: Industry]、Steel Producing [Category: Industry]、Forging [Category: Heat or Machine]、Metal Preparation and Pouring [Category: Foundry]、Petroleum Production and Refining [Category: Industry]、Smelting Copper or Lead [Category: Industry]、Firefighting [Category: Other]、Cleaning Furnaces or Flues [Category: Clean]、Burning Natural Polymers [Category: Burn]、Glass Manufacturing [Category: Industry]、Metal Extraction and Refining [Category: Industry]、Glassblowing [Category: Hobbies]、Smoking cigarettes [Category: Food & Drugs]、Burning biomass fuel for cooking and heating [Category: Environments]、Laboratory chemicals、synthesis of substances.[Sigma-Aldrich、Safety Data Sheet for Benzo、Benzo(a)pyrene、an indirect carcinogen which undergoes metabolism to reactive electrophiles capable of binding covalently to DNA、has been used extensively as a positive control in a variety of short-term tests.、Fuels and related products.、Synthetic Polymer MALDI Matrix Compounds、Substance listed with specific concentration in tattoo ink and、or permanent make up according to EU Commission Regulation 2020、2081. The concentration limit (by weight) is 0.0000005%.、PAHs are released into the environment via the combustion of fossil fuels、coke oven emissions and vehicle exhausts、as well as naturally from forest fires and volcanic eruptions. PAHs from these sources may contaminate nearly water systems. They are also found in coal tar and charbroiled food. (L10)、Use Classification: Food Contaminant -> CONTAMINANT -> JECFA Functional Classes、Industry Uses: Binder、Household Products: Cosmetics product ingredient: Benzo[a]pyrene (BaP) (Benzo[def]chrysene、Benzopyrene)、Reason for Listing:、- Included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907、2006 on the basis of Article 57(d)、Article 57(e)、or Article 57(f) for persistent、bioaccumulative and toxic、or very persistent and very bioaccumulative properties、- Classified by the European Union as a carcinogen、mutagen、and reproductive toxicant Category 1B in Annex VI to Regulation (EC) 1272、2008、- Known to cause cancer and listed under Health and Safety Code section 25249.8 of the California Safe Drinking Water and Toxic Enforcement Act of 1986 (Prop 65)、- Group 1 carcinogen identified by the International Agency for Research on Cancer (IARC). There is sufficient evidence for the carcinogenicity of benzo[a]pyrene in experimental animal studies.、- Identified as priority pollutants in California Water Quality Control Plans under section 303(c) of the federal Clean Water Act and in section 131.38 of title 40 of the Code of Federal Regulations、and identified as pollutants by California or the United States Environmental Protection Agency for one or more water bodies in California under section 303(d) of the federal Clean Water Act and section 130.7 of title 40 of the Code of Federal Regulations、- Identified as Toxic Air Contaminants under sections 93000 and 93001 of title 17 of the California Code of Regulations、- Primary Maximum Contaminant Levels have been established and adopted under section 64431 or section 64444 of chapter 15 of title 22 of the California Code of Regulations、- Identified as “known to be” or “reasonably anticipated to be” a human carcinogen in the 13th Report on Carcinogens、United States Department of Health and Human Services、Public Health Service、National Toxicology Program、- Identified as “carcinogenic to humans”、“likely to be carcinogenic to humans”、or Group B2 carcinogens in the United States Environmental Protection Agency’s Integrated Risk Information System、- The United States Environmental Protection Agency’s Integrated Risk Information System has developed a reference dose or reference concentration based on neurotoxicity、Potential Health Impacts: Bioaccumulation、Carcinogenicity、Environmental Persistence、Genotoxicity、Neurotoxicity、and Reproductive Toxicity、Product count: 1、Information on 3 consumer products that contain Benzo(a)pyrene in the following categories is provided:、• Auto Products、• Inside the Home、Methods of Manufacturing: Synthesis from pyrene and succinic anhydride.、Formulations、Preparations: A reference material of certified high purity is available、U.S. Production: 2023: 1、082、933 lb、2022: 901、772 lb、2021: 1、291、534 lb、2020: 1、051、280 lb、(1978) Not produced commercially in USA、(1982) Not produced commercially in USA、Not produced commercially in the USA.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzo(a)pyrene. National Production Volume: 1、811、363 lb、yr.、SRP: Concern as to validity of data、General Manufacturing Information: Wood Product Manufacturing、Benzo[a]pyrene: ACTIVE、Benzo[a]pyrene occurs naturally in crude oils、shale oils、and coal tars、and is emitted with gases and fly ash from active volcanoes.、There is no commercial production or known use for、benzo(a)pyrene、. Benzo(a)pyrene occurs ubiquitously as a product of incomplete combustion and also occurs in fossil fuels.。
苯并[a]芘 是一种化工化合物，登记 CAS 号为 50-32-8，分子式 C20H12（分子量 252.3）。
登记 CAS 号：50-32-8
其分子式 C20H12 由 20 个碳、12 个氢 组成。
别名/同义词：苯并[a]芘 · Benzo[a]pyrene
苯并[a]芘 的 CAS 登记号为 50-32-8。
分子式 C20H12，分子量 252.3。
别名/同义词：苯并[a]芘、Benzo[a]pyrene。
登记用途：Uses: Used as a research chemical、Not commercially used in the US、[HSDB] Formed during incomplete combustion of organic compounds、Highest levels in aluminum production (up to 100 ug、m3)、then roofing and paving (10-20 ug、then lowest exposures: coal liquefaction、coal-tar distillation、wood treatment with creosote、chimney sweeping、and power plants、[Reference #1]、Aluminum Producing [Category: Industry]、Steel Producing [Category: Industry]、Forging [Category: Heat or Machine]、Metal Preparation and Pouring [Category: Foundry]、Petroleum Production and Refining [Category: Industry]、Smelting Copper or Lead [Category: Industry]、Firefighting [Category: Other]、Cleaning Furnaces or Flues [Category: Clean]、Burning Natural Polymers [Category: Burn]、Glass Manufacturing [Category: Industry]、Metal Extraction and Refining [Category: Industry]、Glassblowing [Category: Hobbies]、Smoking cigarettes [Category: Food & Drugs]、Burning biomass fuel for cooking and heating [Category: Environments]、Laboratory chemicals、synthesis of substances.[Sigma-Aldrich、Safety Data Sheet for Benzo、Benzo(a)pyrene、an indirect carcinogen which undergoes metabolism to reactive electrophiles capable of binding covalently to DNA、has been used extensively as a positive control in a variety of short-term tests.、Fuels and related products.、Synthetic Polymer MALDI Matrix Compounds、Substance listed with specific concentration in tattoo ink and、or permanent make up according to EU Commission Regulation 2020、2081. The concentration limit (by weight) is 0.0000005%.、PAHs are released into the environment via the combustion of fossil fuels、coke oven emissions and vehicle exhausts、as well as naturally from forest fires and volcanic eruptions. PAHs from these sources may contaminate nearly water systems. They are also found in coal tar and charbroiled food. (L10)、Use Classification: Food Contaminant -> CONTAMINANT -> JECFA Functional Classes、Industry Uses: Binder、Household Products: Cosmetics product ingredient: Benzo[a]pyrene (BaP) (Benzo[def]chrysene、Benzopyrene)、Reason for Listing:、- Included in the European Union candidate list of Substances of Very High Concern in accordance with Article 59 of Regulation (EC) 1907、2006 on the basis of Article 57(d)、Article 57(e)、or Article 57(f) for persistent、bioaccumulative and toxic、or very persistent and very bioaccumulative properties、- Classified by the European Union as a carcinogen、mutagen、and reproductive toxicant Category 1B in Annex VI to Regulation (EC) 1272、2008、- Known to cause cancer and listed under Health and Safety Code section 25249.8 of the California Safe Drinking Water and Toxic Enforcement Act of 1986 (Prop 65)、- Group 1 carcinogen identified by the International Agency for Research on Cancer (IARC). There is sufficient evidence for the carcinogenicity of benzo[a]pyrene in experimental animal studies.、- Identified as priority pollutants in California Water Quality Control Plans under section 303(c) of the federal Clean Water Act and in section 131.38 of title 40 of the Code of Federal Regulations、and identified as pollutants by California or the United States Environmental Protection Agency for one or more water bodies in California under section 303(d) of the federal Clean Water Act and section 130.7 of title 40 of the Code of Federal Regulations、- Identified as Toxic Air Contaminants under sections 93000 and 93001 of title 17 of the California Code of Regulations、- Primary Maximum Contaminant Levels have been established and adopted under section 64431 or section 64444 of chapter 15 of title 22 of the California Code of Regulations、- Identified as “known to be” or “reasonably anticipated to be” a human carcinogen in the 13th Report on Carcinogens、United States Department of Health and Human Services、Public Health Service、National Toxicology Program、- Identified as “carcinogenic to humans”、“likely to be carcinogenic to humans”、or Group B2 carcinogens in the United States Environmental Protection Agency’s Integrated Risk Information System、- The United States Environmental Protection Agency’s Integrated Risk Information System has developed a reference dose or reference concentration based on neurotoxicity、Potential Health Impacts: Bioaccumulation、Carcinogenicity、Environmental Persistence、Genotoxicity、Neurotoxicity、and Reproductive Toxicity、Product count: 1、Information on 3 consumer products that contain Benzo(a)pyrene in the following categories is provided:、• Auto Products、• Inside the Home、Methods of Manufacturing: Synthesis from pyrene and succinic anhydride.、Formulations、Preparations: A reference material of certified high purity is available、U.S. Production: 2023: 1、082、933 lb、2022: 901、772 lb、2021: 1、291、534 lb、2020: 1、051、280 lb、(1978) Not produced commercially in USA、(1982) Not produced commercially in USA、Not produced commercially in the USA.、Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzo(a)pyrene. National Production Volume: 1、811、363 lb、yr.、SRP: Concern as to validity of data、General Manufacturing Information: Wood Product Manufacturing、Benzo[a]pyrene: ACTIVE、Benzo[a]pyrene occurs naturally in crude oils、shale oils、and coal tars、and is emitted with gases and fly ash from active volcanoes.、There is no commercial production or known use for、benzo(a)pyrene、. Benzo(a)pyrene occurs ubiquitously as a product of incomplete combustion and also occurs in fossil fuels.。
苯并[a]芘（CAS 50-32-8）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 50-32-8 |
|---|---|
| PubChem CID | 2336 |
| Molecular formula | C20H12 |
| IUPAC name | benzo[a]pyrene |
| UNII (FDA) | 3417WMA06D |
| Molecular Weight | 252.3 |
|---|---|
| XLogP3 | 6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 252.093900383 |
| Monoisotopic Mass | 252.093900383 |
| Topological Polar Surface Area | 0 |
| Heavy Atom Count | 20 |
| Boiling Point | 887 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | BP: 310-312 °C at 10 mm Hg |
| Boiling Point | 496 °C |
| Boiling Point | 5612 °F |
| Melting Point | 349.7 to 351.5 °F (NTP, 1992) |
| Melting Point | 179 °C |
| Melting Point | 178.1 °C |
| Melting Point | 3497-3515 °F |
| Melting Point | 181.1 °C |
| Solubility | In water, 1.62X10-3 mg/L at 25 °C |
benzo[a]pyrene; 50-32-8; 3,4-Benzopyrene; benzo[pqr]tetraphene; BENZO(A)PYRENE; 3,4-Benzpyrene; Benzpyrene; benzo[def]chrysene; 6,7-Benzopyrene; 3,4-Benz[a]pyrene; Benz[a]pyrene; 3,4-BP; 3,4-Benzopirene; 3,4-Benzpyren; Benz(a)pyrene; Benzo(d,e,f)chrysene
| Regulatory & Food Contact | CONTAMINANT: Food Contaminant TRS 806-JECFA 37/27 FAS 28-JECFA 37/301 |
|---|
| Reported hazard statements | H317, H340, H350, H400, H410, H360 (94.5%), H373, H315 |
|---|
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
H340: May cause genetic defects [Danger Germ cell mutagenicity]
Benzo[a]pyrene · CAS 50-32-8 · C20H12. UNII 3417WMA06D. Boiling Point: 887 °F at 760 mmHg (NTP, 1992); Boiling Point: BP: 310-312 °C at 10 mm Hg; Boiling Point: 496 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Benzo[a]pyrene