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苯并咪达韦

CAS 176161-24-3C15H19Cl2N3O4MW 376.2

苯并咪达韦(CAS 176161-24-3):分子式 C15H19Cl2N3O4、分子量 376.2。

产品概览

CAS号176161-24-3
分子式C15H19Cl2N3O4
分子量376.2
LogP2.2

技术档案

这个产品是什么

苯并咪达韦 是一种化工化合物,登记 CAS 号为 176161-24-3,分子式 C15H19Cl2N3O4(分子量 376.2)。

识别信息

登记 CAS 号:176161-24-3

其分子式 C15H19Cl2N3O4 由 15 个碳、19 个氢、2 个氯、3 个氮、4 个氧 组成。

别名/同义词:苯并咪达韦 · BENZIMIDAVIR

常见问题

苯并咪达韦 的 CAS 号是多少?

苯并咪达韦 的 CAS 登记号为 176161-24-3。

苯并咪达韦 的分子式与分子量是多少?

分子式 C15H19Cl2N3O4,分子量 376.2。

苯并咪达韦 还有哪些别名?

别名/同义词:苯并咪达韦、BENZIMIDAVIR。

PubChem 公开数据

苯并咪达韦(CAS 176161-24-3)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number176161-24-3
PubChem CID471161
Molecular formulaC15H19Cl2N3O4
IUPAC name(2S,3S,4R,5S)-2-[5,6-dichloro-2-(propan-2-ylamino)benzimidazol-1-yl]-5-(hydroxymethyl)oxolane-3,4-diol
UNII (FDA)PTB4X93HE1

计算分子描述符

Molecular Weight376.2
XLogP32.2
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass375.0752615
Monoisotopic Mass375.0752615
Topological Polar Surface Area99.8
Heavy Atom Count24

在册的记载用途

    Maribavir is indicated for the treatment of post-transplant cytomegalovirus (CMV) infection (following hematopoietic stem cell transplant or solid organ transplant) which is refractory to standard treatment with [ganciclovir], [valganciclovir], [cidofovir], or [foscarnet]. In the US, patients receiving the treatment should weigh more than 35 kg and be at least 12 years old. In Canada and Europe, maribavir is only approved in adults.Maribavir is an orally available, antiviral agent which inhibits the pUL97 kinase of cytomegalovirus (CMV) and is used to treat refractory forms of post-transplant CMV infection. Maribavir has been associated with low rates of mild-to-moderate serum aminotransferase elevations during therapy but has not been linked to cases of clinically apparent acute liver injury.

    同义词与商品名

    Maribavir; 176161-24-3; Benzimidavir; livtencity; 1263W94; Camvia; maribavirum; BW-1263W94; GW-257406X; (2S,3S,4R,5S)-2-[5,6-dichloro-2-(propan-2-ylamino)benzimidazol-1-yl]-5-(hydroxymethyl)oxolane-3,4-diol; GW-1263; PTB4X93HE1; BW 1263W94; 1263-W-94; DTXSID60170091; GW257406X

    GHS 危害分类

    Reported hazard statementsH302 (100%), H318 (50%), H371 (50%)

    H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

    H318 (50%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

    公开数据库对它的描述

    BENZIMIDAVIR · CAS 176161-24-3 · C15H19Cl2N3O4. UNII PTB4X93HE1.

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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