Bendamustine

CAS 16506-27-7C16H21Cl2N3O2MW 358.3

Bendamustine (CAS 16506-27-7) — formula C16H21Cl2N3O2, molecular weight 358.3.

Product Overview

CAS Number	16506-27-7
Molecular Formula	C16H21Cl2N3O2
Molecular Weight	358.3
LogP	0.44
Applications	Uses: Alkylating drug indicated for the treatment of patients with chronic lymphocytic leukemia, Bandamustine hydrochloride, Bifunctional alkylating agent.[The Merck Index, Fourteenth Edition (2006), Therapeutic category: Antineoplastic, Formulations, Preparations: Parenteral: For injection, for IV infusion only: 100 mg Treanda (Cephalon)., Bendamustine hydrochloride, General Manufacturing Information: Approved for B-cell non-Hodgkin lymphoma

Applications

Documented applications: Uses: Alkylating drug indicated for the treatment of patients with chronic lymphocytic leukemia, Bandamustine hydrochloride, Bifunctional alkylating agent.[The Merck Index, Fourteenth Edition (2006), Therapeutic category: Antineoplastic, Formulations, Preparations: Parenteral: For injection, for IV infusion only: 100 mg Treanda (Cephalon)., Bendamustine hydrochloride, General Manufacturing Information: Approved for B-cell non-Hodgkin lymphoma.

Technical Profile

What this product is

Bendamustine is a chemical compound with CAS registry number 16506-27-7 and molecular formula C16H21Cl2N3O2 (molecular weight 358.3).

Identification

CAS number: 16506-27-7

Its molecular formula C16H21Cl2N3O2 comprises 16 C, 21 H, 2 Cl, 3 N, 2 O atoms.

Also known as: Bendamustine · 苯达莫司汀

Frequently Asked Questions

What is the CAS number of Bendamustine?

The CAS registry number of Bendamustine is 16506-27-7.

What is the molecular formula and molecular weight of Bendamustine?

Molecular formula C16H21Cl2N3O2, molecular weight 358.3.

What other names is Bendamustine known by?

It is also registered under: Bendamustine, 苯达莫司汀.

What are the documented applications of Bendamustine?

Recorded applications: Uses: Alkylating drug indicated for the treatment of patients with chronic lymphocytic leukemia, Bandamustine hydrochloride, Bifunctional alkylating agent.[The Merck Index, Fourteenth Edition (2006), Therapeutic category: Antineoplastic, Formulations, Preparations: Parenteral: For injection, for IV infusion only: 100 mg Treanda (Cephalon)., Bendamustine hydrochloride, General Manufacturing Information: Approved for B-cell non-Hodgkin lymphoma.

PubChem Public Data

Independent reference data for Bendamustine (CAS 16506-27-7), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	16506-27-7
PubChem CID	65628
Molecular formula	C16H21Cl2N3O2
IUPAC name	4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
UNII (FDA)	9266D9P3PQ

Computed descriptors

Molecular Weight	358.3
XLogP3	2.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	9
Exact Mass	357.1010823
Monoisotopic Mass	357.1010823
Topological Polar Surface Area	58.4
Heavy Atom Count	23

Physicochemical values on record

LogP	0.44

Documented uses on record

Synonyms and trade names

Bendamustine; 16506-27-7; Bendamustina; 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid; Bendamustinum; DTXSID2046888; 9266D9P3PQ; 1H-Benzimidazole-2-butanoic acid, 5-(bis(2-chloroethyl)amino)-1-methyl-; DTXCID0026888; 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid; 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid; omega-(1-Methyl-5-bis(beta-chloroethyl)aminobenzimidazole-(2)-butyric acid; 1H-benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl-; 4-(5-(bis(2-chloroethyl)amino)-1-methylbenzimidazol-2-yl)butanoic acid; 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-1,3-benzodiazol-2-yl)butanoic acid; RefChem:54437

GHS hazard classification

Reported hazard statements	H301 (100%), H341 (100%), H351 (100%), H360 (100%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

What the public record says

Bendamustine · CAS 16506-27-7 · C16H21Cl2N3O2. UNII 9266D9P3PQ. LogP: 0.44.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.