AZITHROMYCIN DIHYDRATE（CAS 83905-01-5）：分子式 C38H72N2O12、分子量 749.0；类别 有机化学品。
| CAS号 | 83905-01-5 |
|---|---|
| 分子式 | C38H72N2O12 |
| 分子量 | 749.0 |
| 熔点 | 126 |
| LogP | 3.03 |
| 应用领域 | Uses: MEDICATION、Use (kg) in Switzerland (2009): >250、Use (kg、approx.) in Germany (2009): >2500、exact) in Germany (2009): 4700、Use (kg) in USA (2002): 47600、Use (kg) in France (2004): 4073、Consumption (g per capita) in Switzerland (2009): 0.032、Consumption (g per capita、approx.) in Germany (2009): 0.031、exact) in Germany (2009): 0.057、Consumption (g per capita) in the USA (2002): 0.17、Consumption (g per capita) in France (2004): 0.067、Excretion rate: 1、Calculated removal (%): 31、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: BE 892357、G. Kobrehel、S. Djokic、US 4517359 (1982、1985 both to Sour Pliva)、D.J.M. Allen、K.M. Nepveux、EP 298650、eidem、US 6268489 (1989、2001 both to Pfizer)、Antibiotics are fermentation products and are isolated either as unfinished products or as intermediates、generally solid substances of limited stability. They are purified by methods normally employed in organic chemistry、which include chromatography、crystallization、and precipitation.、Antibiotics、Formulations、Preparations: Table: Azithromycin Dihydrate Preparations [Table#6823] |
| 类别 | Organic Chemicals |
登记用途：Uses: MEDICATION、Use (kg) in Switzerland (2009): >250、Use (kg、approx.) in Germany (2009): >2500、exact) in Germany (2009): 4700、Use (kg) in USA (2002): 47600、Use (kg) in France (2004): 4073、Consumption (g per capita) in Switzerland (2009): 0.032、Consumption (g per capita、approx.) in Germany (2009): 0.031、exact) in Germany (2009): 0.057、Consumption (g per capita) in the USA (2002): 0.17、Consumption (g per capita) in France (2004): 0.067、Excretion rate: 1、Calculated removal (%): 31、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: BE 892357、G. Kobrehel、S. Djokic、US 4517359 (1982、1985 both to Sour Pliva)、D.J.M. Allen、K.M. Nepveux、EP 298650、eidem、US 6268489 (1989、2001 both to Pfizer)、Antibiotics are fermentation products and are isolated either as unfinished products or as intermediates、generally solid substances of limited stability. They are purified by methods normally employed in organic chemistry、which include chromatography、crystallization、and precipitation.、Antibiotics、Formulations、Preparations: Table: Azithromycin Dihydrate Preparations [Table#6823]。
AZITHROMYCIN DIHYDRATE 是一种以碳骨架为基础的有机化合物，登记 CAS 号为 83905-01-5，分子式 C38H72N2O12（分子量 749.0），归属于有机化学品大类化工原料。
登记 CAS 号：83905-01-5
其分子式 C38H72N2O12 由 38 个碳、72 个氢、2 个氮、12 个氧 组成。
别名/同义词：AZITHROMYCIN DIHYDRATE · Azithromycin
所属分类：有机化学品
AZITHROMYCIN DIHYDRATE 的 CAS 登记号为 83905-01-5。
分子式 C38H72N2O12，分子量 749.0。
别名/同义词：AZITHROMYCIN DIHYDRATE、Azithromycin。
登记用途：Uses: MEDICATION、Use (kg) in Switzerland (2009): >250、Use (kg、approx.) in Germany (2009): >2500、exact) in Germany (2009): 4700、Use (kg) in USA (2002): 47600、Use (kg) in France (2004): 4073、Consumption (g per capita) in Switzerland (2009): 0.032、Consumption (g per capita、approx.) in Germany (2009): 0.031、exact) in Germany (2009): 0.057、Consumption (g per capita) in the USA (2002): 0.17、Consumption (g per capita) in France (2004): 0.067、Excretion rate: 1、Calculated removal (%): 31、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: BE 892357、G. Kobrehel、S. Djokic、US 4517359 (1982、1985 both to Sour Pliva)、D.J.M. Allen、K.M. Nepveux、EP 298650、eidem、US 6268489 (1989、2001 both to Pfizer)、Antibiotics are fermentation products and are isolated either as unfinished products or as intermediates、generally solid substances of limited stability. They are purified by methods normally employed in organic chemistry、which include chromatography、crystallization、and precipitation.、Antibiotics、Formulations、Preparations: Table: Azithromycin Dihydrate Preparations [Table#6823]。
所属分类：Organic Chemicals。
AZITHROMYCIN DIHYDRATE（CAS 83905-01-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 83905-01-5 |
|---|---|
| PubChem CID | 447043 |
| Molecular formula | C38H72N2O12 |
| IUPAC name | (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one |
| UNII (FDA) | J2KLZ20U1M |
| Molecular Weight | 749.0 |
|---|---|
| XLogP3 | 4 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 7 |
| Exact Mass | 748.50852574 |
| Monoisotopic Mass | 748.50852574 |
| Topological Polar Surface Area | 180 |
| Heavy Atom Count | 52 |
| Melting Point | 126 |
|---|---|
| Melting Point | 113-115 °C |
| Melting Point | 113 - 115 °C |
| Solubility | 5.14e-01 g/L |
| LogP | 3.03 |
| LogP | log Kow = 4.02 |
| LogP | 4.02 |
| LogP | 0.9 |
| Ionization Efficiency | 5.24 |
| Ionization Efficiency | 2.7 |
azithromycin; Zithromax; 83905-01-5; Hemomycin; Azithromycine; Azasite; Azithromycinum; Zitromax; Azenil; aziromycin; Azithrocin; Azitrocin; Macrozit; Azitromicina; Aruzilina; azithromycin anhydrous
| Reported hazard statements | H317 (97.5%), H334 (96.7%), H372 (28.7%), H400 (29.5%), H410 (30.3%) |
|---|
H317 (97.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H334 (96.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
AZITHROMYCIN DIHYDRATE · CAS 83905-01-5 · C38H72N2O12. UNII J2KLZ20U1M. Melting Point: 126; Melting Point: 113-115 °C; Melting Point: 113 - 115 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: AZITHROMYCIN DIHYDRATE