Azelastine (CAS 58581-89-8) — formula C22H24ClN3O, molecular weight 381.9; category pharmaceutical intermediates and APIs.
Azelastine (CAS 58581-89-8) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C22H24ClN3O comprises 22 C, 24 H, 1 Cl, 3 N, 1 O atoms. Its molecular weight is about 381.9. Reported physicochemical data: melting point around 225, LogP about 4.9. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 58581-89-8 |
|---|---|
| Molecular Formula | C22H24ClN3O |
| Molecular Weight | 381.9 |
| Melting Point | 225 |
| LogP | 4.9 |
| Applications | MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 96.1 |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 96.1.
Azelastine is a pharmaceutical intermediate or API compound with CAS registry number 58581-89-8 and molecular formula C22H24ClN3O (molecular weight 381.9), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 58581-89-8
Its molecular formula C22H24ClN3O comprises 22 C, 24 H, 1 Cl, 3 N, 1 O atoms.
Also known as: Azelastine · 氮卓斯汀
Category: pharmaceutical intermediates and APIs
The CAS registry number of Azelastine is 58581-89-8.
Molecular formula C22H24ClN3O, molecular weight 381.9.
It is also registered under: Azelastine, 氮卓斯汀.
Recorded applications: MEDICATION, Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 96.1.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Azelastine (CAS 58581-89-8), compiled from public chemistry databases.
| CAS Registry Number | 58581-89-8 |
|---|---|
| PubChem CID | 2267 |
| Molecular formula | C22H24ClN3O |
| IUPAC name | 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one |
| UNII (FDA) | ZQI909440X |
| Molecular Weight | 381.9 |
|---|---|
| XLogP3 | 4.4 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 381.1607901 |
| Monoisotopic Mass | 381.1607901 |
| Topological Polar Surface Area | 35.9 |
| Heavy Atom Count | 27 |
| Melting Point | 225 |
|---|---|
| Solubility | 9.20e-03 g/L |
| LogP | 4.9 |
| Dissociation Constants | 9.54 |
azelastine; 58581-89-8; Azelastina; 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one; Azelastinum; 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone; ZQI909440X; NSC-758971; CHEBI:2950; DTXSID6022638; 1(2H)-Phthalazinone, 4-((4-chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-; 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one; A 5610; 4-((4-chlorophenyl)methyl)-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one; Vividrin akut Azelastin; RefChem:54397
| Reported hazard statements | H302 (100%), H312 (100%), H315 (100%), H332 (100%), H335 (100%), H351 (50%), H413 (50%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
Azelastine · CAS 58581-89-8 · C22H24ClN3O. UNII ZQI909440X. Melting Point: 225; Solubility: 9.20e-03 g/L; LogP: 4.9.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 氮卓斯汀