azathioprine usp (CAS 446-86-6) — formula C9H7N7O2S, molecular weight 277.27; category pharmaceutical intermediates and APIs.
azathioprine usp (CAS 446-86-6) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C9H7N7O2S comprises 9 C, 7 H, 7 N, 2 O, 1 S atoms. Its molecular weight is about 277.27. Reported physicochemical data: melting point around 243.5, LogP about 0.1. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 446-86-6 |
|---|---|
| Molecular Formula | C9H7N7O2S |
| Molecular Weight | 277.27 |
| Melting Point | 243.5 |
| LogP | 0.1 |
| Applications | immunosuppressant and anticancer drug, [Kanerva, p. 1753], MEDICATION, Use (kg, approx.) in Germany (2009): >2500 |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: immunosuppressant and anticancer drug, [Kanerva, p. 1753], MEDICATION, Use (kg, approx.) in Germany (2009): >2500.
azathioprine usp is a pharmaceutical intermediate or API compound with CAS registry number 446-86-6 and molecular formula C9H7N7O2S (molecular weight 277.27), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 446-86-6
Its molecular formula C9H7N7O2S comprises 9 C, 7 H, 7 N, 2 O, 1 S atoms.
Also known as: azathioprine usp · 硫唑嘌呤 · Azathioprine
Category: pharmaceutical intermediates and APIs
The CAS registry number of azathioprine usp is 446-86-6.
Molecular formula C9H7N7O2S, molecular weight 277.27.
It is also registered under: azathioprine usp, 硫唑嘌呤, Azathioprine.
Recorded applications: immunosuppressant and anticancer drug, [Kanerva, p. 1753], MEDICATION, Use (kg, approx.) in Germany (2009): >2500.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for azathioprine usp (CAS 446-86-6), compiled from public chemistry databases.
| CAS Registry Number | 446-86-6 |
|---|---|
| PubChem CID | 2265 |
| Molecular formula | C9H7N7O2S |
| IUPAC name | 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine |
| UNII (FDA) | MRK240IY2L |
| Molecular Weight | 277.27 |
|---|---|
| XLogP3 | 0.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 277.03819367 |
| Monoisotopic Mass | 277.03819367 |
| Topological Polar Surface Area | 143 |
| Heavy Atom Count | 19 |
| Melting Point | 243.5 |
|---|---|
| Melting Point | dec 243-244 °C |
| Melting Point | 243.5 °C |
| Solubility | 1.07e+00 g/L |
| LogP | 0.1 |
| LogP | log Kow = 0.10 |
| LogP | 0.7 |
| LogP | 0.89 |
| Dissociation Constants | 7.87 (at 25 °C) |
| Dissociation Constants | pKa = 8.2 |
azathioprine; 446-86-6; Azothioprine; Azanin; Azathioprin; Azatioprin; Azamun; Azasan; Ccucol; Imurek; Muran; NSC-39084; Azathioprinum; Azatioprina; BW 57-322; BW-57-322
| Reported hazard statements | H302 (100%), H315 (88.8%), H319 (88.8%), H335 (87.9%), H340 (62.6%), H350 (100%), H360 (58.9%), H317 |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (88.8%): Causes skin irritation [Warning Skin corrosion/irritation]
Azathioprine · CAS 446-86-6 · C9H7N7O2S. UNII MRK240IY2L. Melting Point: 243.5; Melting Point: dec 243-244 °C; Melting Point: 243.5 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 硫唑嘌呤