阿伏苯宗（CAS 70356-09-1）：分子式 C20H22O3、分子量 310.4。
| CAS号 | 70356-09-1 |
|---|---|
| 分子式 | C20H22O3 |
| 分子量 | 310.4 |
| 熔点 | 83.5 °C |
| LogP | 4.8 |
| 应用领域 | Uses: Used as an ultraviolet sunscreen、[Merck Index]、UV-A blocker、The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed over-the-counter drug products、including avobenzone、approved on the basis of safety and effectiveness by FDA under sections 505 of the Federal Food、Drug、and Cosmetic Act.、Used as a UVA-filter in sun care products、baby sun care products、daily sun protection、decorative cosmetics、allowed use level in USA is 0.5-4%、Provides broad-spectrum protection in skin and sun-care preparations、can be used for the formulation of protective hair-care、medicated skin-care and protective skin-tone preparations、Recommended use levels are 2-3% in sunscreen products and 1-2% in everyday skin-care products.、Use Classification: Fragrance Ingredients、Cosmetics -> Uv filter、Uv absorber、Industry Uses: Photosensitive agent、Fragrance、Consumer Uses: Photosensitive agent、Household Products: Cosmetics product ingredient: Avobenzone、Source: Avobenzone is a synthetic chemical that is effective at blocking UVA radiation、the type of ultraviolet radiation that does not cause sun burn、but can damage skin and cause skin cancer. Avobenzone is found in products such as sunscreens and other cosmetics that have a sun protection factor (SPF).、Potential health impacts: People may be exposed to avobenzone through skin contact or ingestion. Studies have shown that avobenzone absorption into the skin is limited. Some individuals may experience solar dermatitis、or a skin rash、following application of avobenzone and exposure to the sun. UVA blockers such as avobenzone degrade quickly. Sunscreen should therefore be applied frequently and be used in combination with other measures、such as protective clothing.、Product count: 10、Information on 123 consumer products that contain Avobenzone in the following categories is provided:、• Personal Care、Methods of Manufacturing: K.-F. De Polo、Germany 2945125、idem、United States of America 4387089 (1980、1983 both to Givaudan)、Formulations、Preparations: Brand Names: Banana Boat (as a combination product containing Avobenzone、Homosalate、Octisalate、Octocrylene、Oxybenzone)、Bullfrog (as a combination product containing Avobenzone、Coppertone (as a combination product containing Avobenzone、Hawaiian Tropic (as a combination product containing Avobenzone、and、PreSun (as a combination product containing Avobenzone、Octinoxate、Oxybenzone).、U.S. Production: 2023: 8、266、694 lb、2022: 8、500、000 - <10、000、000 lb、2021: 8、2020: 8、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#7085]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). 1、3-Propanedione、1-、General Manufacturing Information: All Other Basic Organic Chemical Manufacturing、All Other Chemical Product and Preparation Manufacturing、1、1-[4-(1、1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-: ACTIVE、Sunscreens are available in a variety of dosage forms and formulations. ... Because these formulations frequently change and the manufacturers often are reluctant to reveal specific ingredients in their formulations、a listing of commercially available sunscreens is not included in this monograph.、Sunscreens |
登记用途：Uses: Used as an ultraviolet sunscreen、[Merck Index]、UV-A blocker、The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed over-the-counter drug products、including avobenzone、approved on the basis of safety and effectiveness by FDA under sections 505 of the Federal Food、Drug、and Cosmetic Act.、Used as a UVA-filter in sun care products、baby sun care products、daily sun protection、decorative cosmetics、allowed use level in USA is 0.5-4%、Provides broad-spectrum protection in skin and sun-care preparations、can be used for the formulation of protective hair-care、medicated skin-care and protective skin-tone preparations、Recommended use levels are 2-3% in sunscreen products and 1-2% in everyday skin-care products.、Use Classification: Fragrance Ingredients、Cosmetics -> Uv filter、Uv absorber、Industry Uses: Photosensitive agent、Fragrance、Consumer Uses: Photosensitive agent、Household Products: Cosmetics product ingredient: Avobenzone、Source: Avobenzone is a synthetic chemical that is effective at blocking UVA radiation、the type of ultraviolet radiation that does not cause sun burn、but can damage skin and cause skin cancer. Avobenzone is found in products such as sunscreens and other cosmetics that have a sun protection factor (SPF).、Potential health impacts: People may be exposed to avobenzone through skin contact or ingestion. Studies have shown that avobenzone absorption into the skin is limited. Some individuals may experience solar dermatitis、or a skin rash、following application of avobenzone and exposure to the sun. UVA blockers such as avobenzone degrade quickly. Sunscreen should therefore be applied frequently and be used in combination with other measures、such as protective clothing.、Product count: 10、Information on 123 consumer products that contain Avobenzone in the following categories is provided:、• Personal Care、Methods of Manufacturing: K.-F. De Polo、Germany 2945125、idem、United States of America 4387089 (1980、1983 both to Givaudan)、Formulations、Preparations: Brand Names: Banana Boat (as a combination product containing Avobenzone、Homosalate、Octisalate、Octocrylene、Oxybenzone)、Bullfrog (as a combination product containing Avobenzone、Coppertone (as a combination product containing Avobenzone、Hawaiian Tropic (as a combination product containing Avobenzone、and、PreSun (as a combination product containing Avobenzone、Octinoxate、Oxybenzone).、U.S. Production: 2023: 8、266、694 lb、2022: 8、500、000 - <10、000、000 lb、2021: 8、2020: 8、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#7085]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). 1、3-Propanedione、1-、General Manufacturing Information: All Other Basic Organic Chemical Manufacturing、All Other Chemical Product and Preparation Manufacturing、1、1-[4-(1、1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-: ACTIVE、Sunscreens are available in a variety of dosage forms and formulations. ... Because these formulations frequently change and the manufacturers often are reluctant to reveal specific ingredients in their formulations、a listing of commercially available sunscreens is not included in this monograph.、Sunscreens。
阿伏苯宗 是一种化工化合物，登记 CAS 号为 70356-09-1，分子式 C20H22O3（分子量 310.4）。
登记 CAS 号：70356-09-1
其分子式 C20H22O3 由 20 个碳、22 个氢、3 个氧 组成。
别名/同义词：阿伏苯宗 · Avobenzone
阿伏苯宗 的 CAS 登记号为 70356-09-1。
分子式 C20H22O3，分子量 310.4。
别名/同义词：阿伏苯宗、Avobenzone。
登记用途：Uses: Used as an ultraviolet sunscreen、[Merck Index]、UV-A blocker、The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed over-the-counter drug products、including avobenzone、approved on the basis of safety and effectiveness by FDA under sections 505 of the Federal Food、Drug、and Cosmetic Act.、Used as a UVA-filter in sun care products、baby sun care products、daily sun protection、decorative cosmetics、allowed use level in USA is 0.5-4%、Provides broad-spectrum protection in skin and sun-care preparations、can be used for the formulation of protective hair-care、medicated skin-care and protective skin-tone preparations、Recommended use levels are 2-3% in sunscreen products and 1-2% in everyday skin-care products.、Use Classification: Fragrance Ingredients、Cosmetics -> Uv filter、Uv absorber、Industry Uses: Photosensitive agent、Fragrance、Consumer Uses: Photosensitive agent、Household Products: Cosmetics product ingredient: Avobenzone、Source: Avobenzone is a synthetic chemical that is effective at blocking UVA radiation、the type of ultraviolet radiation that does not cause sun burn、but can damage skin and cause skin cancer. Avobenzone is found in products such as sunscreens and other cosmetics that have a sun protection factor (SPF).、Potential health impacts: People may be exposed to avobenzone through skin contact or ingestion. Studies have shown that avobenzone absorption into the skin is limited. Some individuals may experience solar dermatitis、or a skin rash、following application of avobenzone and exposure to the sun. UVA blockers such as avobenzone degrade quickly. Sunscreen should therefore be applied frequently and be used in combination with other measures、such as protective clothing.、Product count: 10、Information on 123 consumer products that contain Avobenzone in the following categories is provided:、• Personal Care、Methods of Manufacturing: K.-F. De Polo、Germany 2945125、idem、United States of America 4387089 (1980、1983 both to Givaudan)、Formulations、Preparations: Brand Names: Banana Boat (as a combination product containing Avobenzone、Homosalate、Octisalate、Octocrylene、Oxybenzone)、Bullfrog (as a combination product containing Avobenzone、Coppertone (as a combination product containing Avobenzone、Hawaiian Tropic (as a combination product containing Avobenzone、and、PreSun (as a combination product containing Avobenzone、Octinoxate、Oxybenzone).、U.S. Production: 2023: 8、266、694 lb、2022: 8、500、000 - <10、000、000 lb、2021: 8、2020: 8、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#7085]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). 1、3-Propanedione、1-、General Manufacturing Information: All Other Basic Organic Chemical Manufacturing、All Other Chemical Product and Preparation Manufacturing、1、1-[4-(1、1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-: ACTIVE、Sunscreens are available in a variety of dosage forms and formulations. ... Because these formulations frequently change and the manufacturers often are reluctant to reveal specific ingredients in their formulations、a listing of commercially available sunscreens is not included in this monograph.、Sunscreens。
阿伏苯宗（CAS 70356-09-1）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 70356-09-1 |
|---|---|
| PubChem CID | 51040 |
| Molecular formula | C20H22O3 |
| IUPAC name | 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione |
| UNII (FDA) | G63QQF2NOX |
| Molecular Weight | 310.4 |
|---|---|
| XLogP3 | 4.8 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 6 |
| Exact Mass | 310.15689456 |
| Monoisotopic Mass | 310.15689456 |
| Topological Polar Surface Area | 43.4 |
| Heavy Atom Count | 23 |
| Melting Point | 83.5 °C |
|---|---|
| Vapor Pressure | 0.0000014 [mmHg] |
Avobenzone; 70356-09-1; Parsol 1789; Butyl methoxydibenzoylmethane; Escalol 517; Eusolex 9020; Avobenzona; NeoHeliopan 357; Avobenzonum; 4-TERT-BUTYL-4'-METHOXYDIBENZOYLMETHANE; G63QQF2NOX; 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-; NSC-758680; 1-(p-tert-Butylphenyl)-3-(p-methoxyphenyl)-1,3-propanedione; 1,3-Propanedione, 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)-; 1-(4-(1,1-Dimethylethyl)phenyl)-3-(4-methoxyphenyl)-1,3-propanedione
| Regulatory & Food Contact | CIR / INCI: Uv absorber; Uv filter |
|---|---|
| GHS notification summary | 4.7% (97 / 2086) |
| GHS notification summary | 4.7% (97 / 2086) |
|---|---|
| Reported hazard statements | H413 (90.6%) |
This chemical does not meet GHS hazard criteria for 4.7% (97 of 2086) of reports.
H413 (90.6%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
Avobenzone · CAS 70356-09-1 · C20H22O3. UNII G63QQF2NOX. Melting Point: 83.5 °C; Vapor Pressure: 0.0000014 [mmHg].
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Avobenzone