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阿舒瑞韦

CAS 630420-16-5C35H46ClN5O9SMW 748.3

阿舒瑞韦(CAS 630420-16-5)属医药中间体及原料药类产品,分子式 C35H46ClN5O9S,分子量 748.3。济南圣和化工有限公司常年现货供应该产品,常规纯度 按批次COA提供(不公开发布),可按客户需求安排分装包装,欢迎邮件或来电询价。

产品概览

CAS号630420-16-5
分子式C35H46ClN5O9S
分子量748.3
熔点145-155 ºC
LogP4.9
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域医药中间体及原料药
类别医药中间体及原料药

应用领域

医药中间体及原料药

阿舒瑞韦在医药中间体及原料药领域使用广泛。采购前请确认纯度等级与包装形式,以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

供应说明:阿舒瑞韦 常规包装为按订单/批次确认(不公开发布),储存时应密封置于阴凉干燥处,避免与氧化剂混放。济南圣和化工有限公司 支持国内物流发货,大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择 济南圣和化工有限公司 的理由:产品信息透明(含 CAS、分子式、理化参数)、报价响应快(一个工作日内)、单证齐全(COA/MSS/质检资料按需提供)、支持批量与长期协议供货。如需 阿舒瑞韦 以外的配套原料,也欢迎一并列出需求清单。

常见问题

阿舒瑞韦 的 CAS 号是多少?

阿舒瑞韦 的 CAS 号为 630420-16-5。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

阿舒瑞韦 有什么用途?

主要应用于医药中间体及原料药。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

Asunaprevir · CAS 630420-16-5 · C35H46ClN5O9S. UNII S9X0KRJ00S. Melting Point: 145-155 ºC; Solubility: <50 mg/L.

Identification

CAS Registry Number630420-16-5
PubChem CID16076883
Molecular formulaC35H46ClN5O9S
IUPAC nametert-butyl N-[(2S)-1-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
UNII (FDA)S9X0KRJ00S

Computed Descriptors

Molecular Weight748.3
XLogP34.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count14
Exact Mass747.2704769
Monoisotopic Mass747.2704769
Topological Polar Surface Area191
Heavy Atom Count51
Formal Charge0

Physical & Chemical Properties

Melting Point145-155 ºC
Solubility<50 mg/L

GHS Hazard Classification

Reported hazard statementsH373 (100%)

H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P260, P319, and P501 (click each P-code to see the statement)

Documented Uses

  • Asunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis. Hepatitis C is a liver disease caused by the hepatitis C virus. The chronic state of this condition accounts for 60-80% of the cases from which the risk of cirrhosis of the liver within 20 years is of around 15-30%. The genotype 1 is the most common type of hepatitis C in the United States and the most difficult to treat.
  • Avoid St. John's Wort. This herb induces CYP3A metabolism and may reduce serum levels of asunaprevir. Co-administration of asunaprevir with St. John's Wort is contraindicated.
  • Exercise caution with grapefruit products. Grapefruit inhibits CYP3A metabolism, which may increase the serum concentration of asunaprevir.
  • Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).
  • J - Antiinfectives for systemic use
  • J05 - Antivirals for systemic use

Synonyms

Asunaprevir; 630420-16-5; BMS-650032; sunvepra; BMS 650032; BMS650032; S9X0KRJ00S; DTXSID201026065; asunaprevirum; RefChem:560284; J05AP06; DTXCID201510323; MFCD27987900; Asunaprevir [USAN]; C35H46ClN5O9S; Asunaprevir [USAN:INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Asunaprevir?

CAS 630420-16-5; molecular formula C35H46ClN5O9S; molecular weight — g/mol.

What other names is Asunaprevir known by?

Asunaprevir, 630420-16-5, BMS-650032, sunvepra, BMS 650032, BMS650032.

Is Asunaprevir classified as hazardous?

Hazard statements reported: H373.

What are the key physical properties of Asunaprevir?

Melting Point: 145-155 ºC; Solubility: <50 mg/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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